Defcort 1 Mg Tablet ( 10 Tab )
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Source ID: 254783
Description
DEFCORT 1 MG TABLET
DEFCORT 1 MG TABLET, manufactured by MACLEODS PHARMACEUTICALS LTD., is a corticosteroid medication known for its anti-inflammatory and immunosuppressant properties. Its active ingredient is Deflazacort.
Composition
- Active Ingredient: Deflazacort 1 mg
Uses DEFCORT 1 MG TABLET is prescribed for a wide range of medical conditions, primarily those involving inflammation or requiring immune system suppression:
- Inflammatory Conditions: Includes arthritis, ankylosing spondylitis, asthma, inflammatory bowel disease (Crohn's disease, ulcerative colitis), uveitis, and various allergies.
- Autoimmune Conditions: Such as Duchenne muscular dystrophy (DMD), psoriasis, rheumatoid arthritis, eczema, atopic dermatitis, lupus, and multiple sclerosis.
- Other Applications: May be used in the treatment of certain cancers (e.g., leukemia, lymphoma, multiple myeloma), to prevent organ rejection after transplants, and for kidney problems like nephrotic syndrome or blood disorders (anaemia, thrombocytopenia).
Dosage and Administration
- DEFCORT 1 MG TABLET should be taken exactly as advised by your doctor.
- It can be taken with or without food, though taking it with food may help prevent an upset stomach.
- Swallow the tablet whole with water; do not chew, crush, or break it.
- It is generally recommended to take the medicine at the same time each day for consistent effectiveness.
- Do not stop taking DEFCORT 1 MG TABLET suddenly, as this can worsen symptoms; your doctor will gradually reduce the dose.
- Typical adult dosage for allergic and inflammatory disorders can be up to 120 mg daily, while children may be prescribed 0.25-1.5 mg/kg/day on alternate days, as directed by a physician.
Side Effects Common side effects may include:
- Increased appetite and weight gain
- Frequent urge to urinate
- Cushing syndrome (puffy face appearance)
- Headache, indigestion, muscle weakness
- Mood changes, such as irritability or depression
- Acne, abnormal or increased facial hair growth, skin redness, stretch marks
- Nausea, vomiting, diarrhea, abdominal pain
- Increased risk of infections
Serious side effects, though rare, warrant immediate medical attention, including signs of severe allergic reaction (swelling, difficulty breathing), stomach ulcers or bleeding, or severe abdominal pain.
Precautions
- Inform your doctor about any existing medical conditions, including diabetes, heart disease, liver or kidney problems, peptic ulcers, tuberculosis, hypertension, osteoporosis, myasthenia gravis, or psychiatric illnesses.
- DEFCORT 1 MG TABLET can suppress the immune system, making it harder to fight off infections. Report any signs of infection (e.g., fever, sore throat) to your doctor.
- Avoid consuming alcohol as it may increase the risk of stomach ulcers and bleeding.
- Use with caution in children, as it may affect growth.
- Pregnant and breastfeeding women should consult their doctor before using this medicine.
- The medicine may cause dizziness or blurred vision; exercise caution when driving or operating machinery until you know how it affects you.
- Inform your doctor about all other medications you are taking, including herbal supplements, as interactions can occur with drugs for diabetes, hypertension, fungal infections, blood thinners, and others. Avoid live vaccines while on this medication.
Storage Store DEFCORT 1 MG TABLET below 25°C or at room temperature, protected from moisture and heat. Keep it out of the reach of children.
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Frequently Asked Questions
DEFCORT 1 MG TABLET contains Deflazacort, which is a corticosteroid medication. It is primarily used for its anti-inflammatory and immunosuppressant properties.
Here are some frequently asked questions about DEFCORT 1 MG TABLET:
What is DEFCORT 1 MG TABLET used for?
DEFCORT 1 MG TABLET is used to treat a wide range of inflammatory and autoimmune conditions. These include allergic conditions, asthma, rheumatoid arthritis, inflammatory skin diseases (like psoriasis and eczema), and other autoimmune diseases where the body's immune system attacks its own tissues. It is also used to manage Duchenne Muscular Dystrophy (DMD) and to suppress the immune system in transplant patients to prevent organ rejection.
How does DEFCORT 1 MG TABLET work?
DEFCORT 1 MG TABLET is a prodrug, meaning it's an inactive form that gets converted in the body to its active metabolite, 21-desacetyldeflazacort. This active form binds to glucocorticoid receptors, leading to anti-inflammatory and immunosuppressive effects. It works by inhibiting the release of substances that cause swelling and pain, and by modifying the immune system's response to various conditions.
What is the usual dosage of DEFCORT 1 MG TABLET?
The dosage of DEFCORT 1 MG TABLET is determined by your doctor based on your body weight and the specific condition being treated. For Duchenne Muscular Dystrophy, the usual dose for adults and children 2 years and older is approximately 0.9 mg per kilogram of body weight once daily. It can be taken with or without food, but taking it with food may help avoid an upset stomach. It's important to take it regularly at the same time each day for maximum effectiveness. Do not stop taking it abruptly without consulting your doctor, as the dose may need to be gradually decreased.
What are the possible side effects of DEFCORT 1 MG TABLET?
Common side effects can include increased appetite, weight gain (especially around the face), frequent urge to urinate, cough, upper respiratory tract infection, abnormal hair growth, obesity, headache, indigestion, irregular periods, muscle weakness, acne, and mood changes (such as irritability or depression). It can also increase blood sugar levels and may make it harder to fight off infections due to its immunosuppressant properties. If any side effects bother you or if you notice signs of infection (like fever or sore throat), inform your doctor.
Is DEFCORT 1 MG TABLET safe during pregnancy or breastfeeding?
DEFCORT 1 MG TABLET may be unsafe to use during pregnancy and is generally not recommended unless prescribed by a doctor who has weighed the potential benefits and risks. Limited human data suggests that the drug may pass into breast milk and could harm the baby, so it is probably unsafe during breastfeeding. Consulting your doctor is essential if you are pregnant, planning a pregnancy, or breastfeeding.
Can DEFCORT 1 MG TABLET be taken with other medications?
DEFCORT 1 MG TABLET can interact with various medications. It's crucial to inform your doctor about all medicines you are taking, including prescribed, non-prescribed, herbal medicines, and dietary supplements. Particular caution is advised with medicines for diabetes (as Defcort can increase blood sugar), hypertension, asthma, fungal infections, viral infections, water pills, antacids, painkillers (NSAIDs can increase the risk of gastrointestinal bleeding), immunosuppressants (can further suppress the immune system), blood thinners like warfarin, and anti-tuberculosis medicines like rifampicin. Live vaccines should be avoided during treatment as Defcort can weaken the immune system.
What precautions should be taken?
Inform your doctor about your medical history, especially if you have conditions such as diabetes, hypertension, heart diseases, liver or kidney diseases, peptic ulcers, fits, weak bones (osteoporosis), thyroid problems, depression, psychiatric illnesses, or a history of tuberculosis. Avoid consuming alcohol as it may heighten the risk of stomach ulcers and bleeding. Due to immune suppression, avoid contact with people who are sick or have infections. Do not stop the medicine abruptly.
What happens if a dose is missed?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.
How should it be stored?
DEFCORT 1 MG TABLET should be stored below 25°C, away from moisture and heat, and kept out of the reach of children and pets. Ensure it is in its original packaging and check the expiry date before use.