Phenergan 25 Tablet

Phenergan 25 Tablet, containing promethazine hydrochloride, is a medication used for various conditions, primarily due to its antihistamine and sedative properties. Here are some frequently asked questions about Phenergan 25 Tablet:

What is Phenergan 25 Tablet used for?

Phenergan 25 Tablet is primarily used to treat allergic conditions such as hay fever, allergic rhinitis, and skin rashes like urticaria (hives). It is also used as an antiemetic to prevent and treat nausea and vomiting, including that caused by motion sickness or after surgery. Additionally, it can be used for short-term treatment of insomnia in adults and as a sedative for children aged 6 years and above (though elixir form is often recommended for children).

How does Phenergan 25 Tablet work?

Phenergan 25 Tablet contains promethazine hydrochloride, which is a first-generation antihistamine belonging to the phenothiazine group of medicines. It works by blocking the action of histamine, a natural substance in the body that causes allergic symptoms like itching, watery eyes, and sneezing. It also acts directly on several areas of the brain to produce a calming effect, help with relaxation, and prevent nausea and vomiting.

What is the usual dosage of Phenergan 25 Tablet?

The dosage of Phenergan 25 Tablet varies depending on the condition being treated and individual response.

• For allergic conditions: Adults typically take 25 mg as a single dose at night, or 12.5 mg before meals and at bedtime. The maximum daily dose for allergic conditions can be up to 25 mg twice a day, if required.
• For nausea and vomiting: The average adult dose is 25 mg, which may be repeated every 4 to 6 hours as needed.
• For motion sickness: Adults can take 25 mg the night before travel, and repeat after 6-8 hours as required. The initial dose should be taken one-half to one hour before anticipated travel.
• For short-term insomnia or sedation: Adults usually take 25 mg as a single night-time dose, which can be increased to 50 mg if necessary. Phenergan 25 mg tablets are generally not for use in children under 6 years of age. It should not be used for longer than 7 days without medical advice.

What are the possible side effects of Phenergan 25 Tablet?

Common side effects include drowsiness, dizziness, dry mouth, blurred vision, headache, tiredness, disorientation, and sometimes nightmares. More serious but less common side effects can include severe drowsiness, weak or shallow breathing, confusion, agitation, hallucinations, seizures, fast or slow heartbeats, and jaundice (yellowing of the skin or eyes). Allergic reactions, including rash, itching, and difficulty breathing, may also occur.

Is Phenergan 25 Tablet safe during pregnancy or breastfeeding?

The use of Phenergan 25 Tablet is generally not recommended during pregnancy, especially during late pregnancy, unless the potential benefits outweigh the potential risks. High doses during late pregnancy have been linked to prolonged neurological disturbances in the infant. It should also be avoided in women of childbearing potential not using contraception. Phenergan is excreted in breast milk and is not recommended for use during breastfeeding due to risks of neonatal irritability and excitement, and potential harm to the baby.

Can Phenergan 25 Tablet be taken with other medications?

Phenergan 25 Tablet can interact with many other medications, potentially increasing side effects or affecting how the medicine works.

• CNS Depressants: Avoid or use with caution with other medications that cause drowsiness, such as alcohol, sedatives, hypnotics, narcotic pain medicines, and tranquilizers, as this can enhance the sedative effects and lead to severe drowsiness or breathing problems.
• Anticholinergic agents: Concomitant use with drugs having anticholinergic properties (e.g., some medications for irritable bowel syndrome, asthma, or depression) can increase the risk of side effects like dizziness, dry mouth, and blurred eyesight.
• MAO Inhibitors: Phenergan should not be taken if you are currently taking or have taken a monoamine oxidase inhibitor (MAOI) for depression within the last 14 days, as this combination can cause severe drowsiness.
• Other interactions: Inform your doctor if you are taking medicines for mental health problems, irregular heartbeats, epilepsy, or certain pain relievers like aspirin, as Phenergan may affect their efficacy or mask their side effects.

What precautions should be taken while using Phenergan 25 Tablet?

• Drowsiness: Phenergan can cause significant drowsiness, dizziness, and blurred vision. Do not drive or operate heavy machinery until you know how the medicine affects you.
• Alcohol: Avoid alcohol consumption during treatment as it can increase the sedative effects.
• Photosensitivity: Phenergan can make your skin more sensitive to sunlight. Avoid strong sunlight or ultraviolet light exposure during or shortly after treatment, and consider using sunscreen or protective clothing.
• Underlying conditions: Use with caution in patients with asthma, bronchitis, or other breathing difficulties, severe coronary artery disease, epilepsy, glaucoma, or liver/kidney problems.
• Duration of use: Do not take Phenergan 25 Tablet for longer than 7 days without consulting a doctor.
• Medical tests: Phenergan may affect the results of certain pregnancy tests and skin allergy tests. Inform your doctor or pharmacist if you are taking Phenergan before such tests.

What happens if a dose is missed?

If you miss a dose of Phenergan 25 Tablet:

• For allergic conditions: Take the medicine as soon as you remember, then continue with your regular schedule.
• For sedation or sleeping problems: Miss that dose and take the next evening's dose as usual. Do not take a double dose to make up for a forgotten dose. If you are unsure, consult your doctor or pharmacist.

How should Phenergan 25 Tablet be stored?

Phenergan 25 Tablet should be stored below 30°C and kept in the original carton to protect it from light. Keep this medicine out of the sight and reach of children.

Are there any age restrictions for Phenergan 25 Tablet?

Phenergan 25mg tablets are not recommended for use in children under the age of 6 years due to the potential for serious breathing difficulties and central nervous system events. For children between 6 and 10 years, the elixir form is often recommended. Promethazine must not be used in children less than two years of age because of the potential for fatal respiratory depression.