Antidep Tab
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Source ID: 252502
Description
ANTIDEP TAB by TORRENT PHARMACEUTICALS LTD
ANTIDEP TAB is a medication manufactured by Torrent Pharmaceuticals Ltd. primarily prescribed for certain mood disorders and childhood conditions.
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Name: Antidep Tablet
- Brand Name: Antidep
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Composition: The active ingredient in Antidep Tablet is Imipramine Hydrochloride. It is available in strengths such as 25mg and 75mg. Imipramine belongs to a class of medicines known as tricyclic antidepressants. It works by increasing the activity of natural substances like norepinephrine and serotonin in the brain, which are crucial for mental balance and mood regulation.
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Uses:
- Depression: Antidep Tablet is used to treat symptoms of depressive illness, including various forms of depression such as neurotic, reactive, and severe potentially suicidal depression. It helps stabilize mood and enhance emotional well-being.
- Nocturnal Enuresis (Bed-wetting): It is also used to relieve nocturnal enuresis in children aged 6 years and older by relaxing the urinary bladder muscle and lightening sleep.
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Dosage and Administration: Antidep Tablet should be taken orally as prescribed by a physician. It can be taken with or without food. The main dose is often recommended to be taken at night to help mitigate drowsiness. Do not crush or chew the tablet.
- Adults: Typically 25mg up to three times daily, increasing stepwise to 150-200mg daily. The maintenance dose is usually 50-100mg per day.
- Elderly: Treatment is usually initiated with 10mg daily, increased to 30-50mg daily.
- Children (for nocturnal enuresis only):
- 6-7 years: 25mg daily.
- 8-11 years: 25-50mg daily.
- Over 11 years: 50-75mg daily.
- It is not recommended for children under 6 years of age. Do not stop taking the medication abruptly, as it can lead to withdrawal symptoms.
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Side Effects:
- Common Side Effects: Dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast, weakness, nervousness, dizziness, headache, blurred vision, constipation, diarrhea, sleepiness, decreased sexual drive or ability, decreased concentration and memory.
- Serious Side Effects: Suicidal thoughts or attempts, worsening of depression or anxiety, irregular heartbeats, seizures, coma (in overdose), orthostatic hypotension (sudden drop in blood pressure on standing), tachycardia, hallucinations, cardiac conduction abnormalities, black tongue, bone marrow suppression, jaundice, and altered liver function. Seek immediate medical attention if you experience serious side effects or overdose symptoms.
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Precautions:
- Contraindications: Do not take Antidep if allergic to imipramine or other tricyclic antidepressants, if taking monoamine oxidase inhibitors (MAOIs) or within 14 days of taking them, if you have heart disease (including recent heart attack, heart block, or arrhythmias), severe liver disease, porphyria, narrow-angle glaucoma, urine retention, or mania.
- Pregnancy and Breastfeeding: Not generally recommended during pregnancy due to potential risks to the developing baby. It may pass into breast milk, so consult a doctor if breastfeeding.
- Alcohol: Avoid consuming alcohol as it can increase drowsiness and other side effects.
- Driving and Operating Machinery: May cause impaired alertness, drowsiness, or blurred vision. Avoid driving or operating machinery until you know how the medicine affects you.
- Other Warnings: Use with caution in patients with impaired renal or hepatic function, epilepsy, history of brain damage, enlarged prostate, overactive thyroid, low blood pressure, or panic attacks. Regular blood tests may be needed to monitor blood cell count, sodium, and sugar levels. Inform your doctor if you experience suicidal thoughts or significant behavioral/mood changes.
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Storage: Store Antidep Tablet at room temperature, between 20 and 25 degrees C (68 and 77 degrees F). Keep it away from heat, moisture, and direct sunlight. Ensure it is kept out of reach and sight of children and pets.
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Frequently Asked Questions
Here are some frequently asked questions about ANTIDEP TAB by Torrent Pharmaceuticals Ltd. (Imipramine):
What is ANTIDEP TAB used for?
ANTIDEP TAB, which contains Imipramine, is primarily used to treat depression. Additionally, it is prescribed for the management of bed-wetting (nocturnal enuresis) in children aged 6 years and older.
How does ANTIDEP TAB work?
ANTIDEP TAB belongs to a class of medicines called tricyclic antidepressants. It works by increasing the activity and levels of certain natural substances (neurotransmitters) in the brain, such as norepinephrine and serotonin, which are essential for mental balance and mood regulation. For bed-wetting, it helps by relaxing the urinary bladder muscles and can lighten sleep.
What are the possible side effects of ANTIDEP TAB?
Common side effects of ANTIDEP TAB may include dry mouth, nausea, vomiting, increased blood pressure, lack of coordination, swelling of the breast, weakness, blurred vision, dizziness, drowsiness, difficulty in urination, constipation, increased heart rate, and weight gain. Initially, it may also cause a sudden drop in blood pressure when changing positions.
Is ANTIDEP TAB safe during pregnancy or breastfeeding?
ANTIDEP TAB is generally not recommended for use during pregnancy, especially during the last three months, as it may cause complications in the newborn, such as breathing difficulties, colic, lethargy, irritability, blood pressure changes, tremors, or spasms. It is important to inform your doctor if you are pregnant or breastfeeding.
Can ANTIDEP TAB be taken with other medications?
ANTIDEP TAB can interact with several medications. It is crucial to inform your doctor about all other medicines you are taking, including herbal remedies. Significant interactions can occur with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), medicines for epilepsy (e.g., carbamazepine, phenytoin), benzodiazepines, disulfiram, nicotine replacement therapy, methylphenidate, thyroid medications, non-steroidal anti-inflammatory drugs (NSAIDs), and St. John's wort. Alcohol consumption should also be avoided as it can worsen symptoms and increase drowsiness.
What precautions should be taken while taking ANTIDEP TAB?
Do not stop taking ANTIDEP TAB suddenly without consulting your doctor, as this can lead to withdrawal symptoms or a relapse of depression. This medicine may cause drowsiness, so avoid driving or activities requiring mental concentration until you know how it affects you. Your doctor may recommend regular blood tests to monitor blood cell count, sodium, and sugar levels. Caution is advised for individuals with cardiovascular diseases, seizure disorders, diabetes, glaucoma, kidney or liver disease, pheochromocytoma, or a history of bipolar disorder. Inform your doctor if you notice behavioral changes or suicidal thoughts.
What is the usual dosage of ANTIDEP TAB?
The specific dose and duration of treatment with ANTIDEP TAB will be determined by your doctor based on your medical condition and response. It is often recommended to take the main dose at night due to its potential to cause drowsiness. Do not exceed the prescribed dose.
What happens if a dose of ANTIDEP TAB is missed?
If you miss a dose of ANTIDEP TAB, take it as soon as you remember. However, do not take extra doses in one day to compensate for a missed dose. Continue with your next dose at the regular scheduled time.
How long does it take for ANTIDEP TAB to work, and for how long should it be taken?
Patients typically begin to feel better two to four weeks after starting ANTIDEP TAB, though it can take up to eight weeks to experience the full benefits. Sleep and appetite may improve earlier. If prescribed for depression, you will usually need to continue taking it for at least 6 to 12 months after your symptoms improve to prevent relapse.
How should ANTIDEP TAB be stored?
ANTIDEP TAB should be kept out of the reach and sight of children. It should be stored at room temperature, ideally below 30°C.