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Desval Er 500 Mg Tablet (10 Tab)
24.8% OFF

Desval Er 500 Mg Tablet (10 Tab)

Divalproex (500mg)

Source ID: 245467

199.73

150.20

(Inclusive of all taxes)
Delivery Details
PCMC

Batch

-

PKG

10 TABLETS

Expiry

-

MRP

₹199.73

Stock

18

Discount

24.8%

Description

DESVAL ER 500 MG TABLET

DESVAL ER 500 MG TABLET is an extended-release medication manufactured by Eris Lifesciences Limited, primarily used as an anticonvulsant and mood stabilizer.

  • Composition The active ingredient in DESVAL ER 500 MG TABLET is Divalproex (500mg). Divalproex is a stable coordination compound comprised of sodium valproate and valproic acid.

  • Uses DESVAL ER 500 MG TABLET is prescribed for a range of neurological and psychiatric conditions, including:

    • Epilepsy/Seizures: It is used for the treatment of various forms of epilepsy, including simple, complex partial, and complex absence seizures, as well as adjunctive therapy in multiple seizure types such as tonic-clonic and myoclonic seizures. It works by decreasing excessive and abnormal nerve activity in the brain.
    • Bipolar Disorder: It is effective in managing manic episodes associated with bipolar disorder by stabilizing mood fluctuations.
    • Migraine Prevention: It can be used for the prophylaxis of migraine headaches.
    • Trigeminal Neuralgia: It may also be used in the treatment of trigeminal neuralgia.
  • Dosage and Administration DESVAL ER 500 MG TABLET is an extended-release tablet designed for oral administration. It should be swallowed whole with a glass of water and not crushed, chewed, or broken. The tablet can be taken with or without food, but consistency in timing each day is recommended for optimal benefits. Your doctor will determine the appropriate dose and frequency based on your condition and response to treatment. It is crucial not to stop this medication abruptly, as it may lead to a worsening of seizures.

  • Side Effects Common side effects may include:

    • Nausea, vomiting, abdominal pain, diarrhea, constipation
    • Headache, dizziness, drowsiness, weakness, tremors, blurred vision, double vision, memory impairment
    • Weight changes (gain or loss), hair loss, increased appetite, flu-like symptoms Serious side effects, though less common, can include liver injury (especially within the first six months of treatment), pancreatitis, suicidal thoughts, thrombocytopenia (low blood platelets), hyperammonemia (high ammonia levels), and hypersensitivity reactions.
  • Precautions

    • Pregnancy and Breastfeeding: DESVAL ER 500 MG TABLET is not recommended during pregnancy due to the risk of serious birth defects. Women of childbearing potential should use effective contraception. Consult your doctor if you are breastfeeding.
    • Liver and Pancreatic Conditions: It is contraindicated in individuals with severe liver disease or a history of pancreatitis. Regular monitoring of liver function is essential, particularly during the initial months of treatment.
    • Alcohol Consumption: Avoid or limit alcohol intake, as it can intensify side effects like dizziness and drowsiness and increase the risk of seizures.
    • Driving and Operating Machinery: This medication can cause dizziness and affect cognitive and motor skills; therefore, caution is advised when driving or operating machinery.
    • Medical History: Inform your doctor about any history of heart problems, kidney disease, depression, suicidal thoughts, or other medical conditions.
    • Drug Interactions: Inform your doctor about all other medications you are taking, as some drugs can interact with Divalproex.
    • Children: Use with caution in children, especially those under 2 years of age, due to a higher risk of liver intoxication.
    • Long-term Use: Prolonged use may lead to osteoporosis and an increased risk of bone fractures.
  • Storage Store DESVAL ER 500 MG TABLET at room temperature (below 30°C) in a cool, dry place, away from direct sunlight and moisture. Keep it out of the reach of children and pets.

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Frequently Asked Questions

Here are frequently asked questions about DESVAL ER 500 MG TABLET:

What is DESVAL ER 500 MG TABLET used for?

DESVAL ER 500 MG TABLET is primarily used to treat epilepsy (seizures), manic episodes associated with bipolar disorder, and to prevent migraine headaches. It can be used alone or in combination with other medications.

How does DESVAL ER 500 MG TABLET work?

This medicine contains Divalproex, which works by increasing the levels of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain. By enhancing GABA activity, it helps to calm overactive nerve signals, stabilize brain activity, control seizures, stabilize mood in bipolar disorder, and reduce the frequency and intensity of migraine headaches.

What is the usual dosage for DESVAL ER 500 MG TABLET?

The dosage of DESVAL ER 500 MG TABLET is determined by your doctor based on your specific condition and response to the medicine. It should be taken exactly as prescribed, usually at the same time each day for maximum benefit. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. It can be taken with or without food. For epilepsy, the initial dose is often 10-15 mg/kg/day, which may be increased gradually, but typically should not exceed 60 mg/kg/day. For migraine prevention, an initial dose of 500 mg once daily for a week may be prescribed, potentially increasing up to 1000 mg/day if needed.

What are the possible side effects of DESVAL ER 500 MG TABLET?

Common side effects may include dizziness, drowsiness, nausea, vomiting, diarrhea, constipation, headache, abdominal pain, hair loss, weight gain, tremors (uncontrollable shaking), and blurred vision. Most of these are temporary and usually resolve over time. More serious side effects can include liver damage, pancreatitis, and changes in mood or behavior, including suicidal thoughts. If you experience persistent or severe side effects, or any concerning symptoms, consult your doctor immediately.

Is DESVAL ER 500 MG TABLET safe during pregnancy or breastfeeding?

DESVAL ER 500 MG TABLET is generally not recommended during pregnancy due to definite evidence of risk to the developing baby, potentially causing birth defects or developmental problems. If you are pregnant or planning to conceive, you should consult your doctor before taking this medicine, as they may consider a safer alternative. For breastfeeding mothers, caution is advised as small quantities of the medicine may pass into breast milk. It's important to discuss the potential risks and benefits with your doctor.

Can DESVAL ER 500 MG TABLET be taken with other medications?

DESVAL ER 500 MG TABLET can interact with several other medications. For example, salicylates (like aspirin), carbapenem antibiotics (e.g., meropenem), other anticonvulsants (e.g., phenytoin, phenobarbital, lamotrigine), blood thinners (e.g., warfarin), and benzodiazepines (e.g., diazepam) may interact, altering effectiveness or increasing side effects. Other interacting medications can include lomitapide, mipomersen, bexarotene, and sodium oxybate. Always inform your doctor about all medicines you are currently taking, including over-the-counter drugs and herbal supplements, to ensure safe co-administration.

What precautions should be taken while using DESVAL ER 500 MG TABLET?

Avoid or limit alcohol consumption while taking DESVAL ER 500 MG TABLET, as it can intensify side effects like dizziness and drowsiness. Exercise caution if you have pre-existing conditions such as liver disease, pancreatic disorders, or urea cycle disorders, as this medicine could worsen them. Since it can cause dizziness and drowsiness, avoid driving or operating heavy machinery until you know how it affects you. Do not stop taking the medicine suddenly, as this can lead to withdrawal symptoms or worsen your condition, including triggering seizures. Your doctor may recommend regular blood tests to monitor drug levels and liver function, especially during the first six months of treatment.

What happens if a dose of DESVAL ER 500 MG TABLET is missed?

If you miss a dose of DESVAL ER 500 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing routine. Do not double the dose to compensate for a missed one, as this can increase the risk of side effects. Consistency in taking the medication is crucial to its effectiveness.

How should DESVAL ER 500 MG TABLET be stored?

DESVAL ER 500 MG TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. It should also be kept out of the sight and reach of children and pets.