Istavel Empa 10mg Tab

ISTAVEL EMPA 10MG TABLET is a combination medication used in the management of Type 2 Diabetes Mellitus.

Name

• Brand Name: ISTAVEL EMPA 10MG TABLET
• Common Name: Empagliflozin/Sitagliptin

Composition Each tablet contains:

• Empagliflozin: 10 mg
• Sitagliptin: 100 mg

Uses ISTAVEL EMPA 10MG TABLET is primarily prescribed for adults with Type 2 Diabetes Mellitus to help control high blood sugar levels when diet and exercise alone are not sufficient. It works by helping the kidneys remove excess sugar from the body through urine (Empagliflozin) and by improving the body's insulin response and reducing sugar production by the liver (Sitagliptin). This combination may also offer benefits for cardiovascular and kidney health.

Dosage and Administration Typically, ISTAVEL EMPA 10MG TABLET is taken once daily, with or without food. It is often recommended to take it after meals. For optimal results, it should be taken at the same time each day. The tablet should be swallowed whole with water. Do not stop taking the medicine without consulting your doctor.

Side Effects Common side effects may include:

• Urinary tract infections (UTIs)
• Fungal infections (especially genital)
• Upper respiratory tract infections
• Headache
• Joint pain
• Nausea
• Sore throat

Serious side effects, though less common, can include dehydration and hypoglycemia (low blood sugar), especially when used with other diabetes medications. Seek medical attention if you experience symptoms like nausea, vomiting, stomach pain, excessive thirst, or unusual sleepiness.

Precautions

• ISTAVEL EMPA is not for use in Type 1 Diabetes Mellitus or diabetic ketoacidosis.
• Exercise caution in patients with kidney or liver problems.
• Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, as the medicine may be unsafe during these periods.
• Patients at risk of dehydration (e.g., due to vomiting, diarrhea, or diuretic use) should be monitored.
• Avoid excessive alcohol consumption, as it can lower blood sugar and increase the risk of lactic acidosis.
• Inform your doctor about all other medications, supplements, and pre-existing conditions.

Storage Store the medicine at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children.

ISTAVEL EMPA 10MG TAB is a combination medication containing Empagliflozin (10mg) and Sitagliptin (100mg), primarily used to manage Type 2 Diabetes Mellitus.

What is ISTAVEL EMPA 10MG TAB used for?

ISTAVEL EMPA 10MG TAB is prescribed for adults with Type 2 Diabetes Mellitus to lower blood sugar levels, especially when diet and exercise alone are insufficient. Empagliflozin, one of its components, is also used to reduce the risk of cardiovascular death, hospitalization for heart failure, and the progression of chronic kidney disease in relevant adult patients.

How does ISTAVEL EMPA 10MG TAB work?

This medication combines two active ingredients with different mechanisms. Empagliflozin works by inhibiting the sodium-glucose co-transporter-2 (SGLT2) in the kidneys, which increases the amount of glucose excreted in the urine, thereby lowering blood sugar. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances the body's natural ability to lower blood sugar by increasing the release of insulin when blood sugar levels are high and reducing the amount of sugar produced by the liver.

What is the usual dosage for ISTAVEL EMPA 10MG TAB?

The usual dose for ISTAVEL EMPA 10MG TAB is one tablet (Empagliflozin 10mg + Sitagliptin 100mg) taken once daily. It can be taken with or without food, but some sources suggest taking it after meals to reduce potential stomach upset. Your doctor may adjust the dose based on your individual needs and response to treatment.

What are the possible side effects of ISTAVEL EMPA 10MG TAB?

Common side effects may include genital yeast infections and urinary tract infections. More serious, but less common, side effects can include dehydration, low blood pressure (especially if on diuretics), diabetic ketoacidosis (a serious condition with high ketone levels in the blood), and in rare cases, a serious bacterial infection called Fournier's gangrene, or lower limb amputations. Allergic reactions are also possible. It's important to report any concerning symptoms to your doctor.

Is ISTAVEL EMPA 10MG TAB safe during pregnancy or breastfeeding?

ISTAVEL EMPA 10MG TAB is generally not recommended during the second and third trimesters of pregnancy due to potential risks to the developing fetal kidneys. It is also not recommended during breastfeeding as it is unknown how much of the medication passes into breast milk and its potential effect on the infant. If you are pregnant, planning to become pregnant, or breastfeeding, discuss alternative treatments with your doctor.

Can ISTAVEL EMPA 10MG TAB be taken with other medications?

Caution is advised when taking ISTAVEL EMPA 10MG TAB with certain other medications. It can interact with diuretics (water pills), potentially increasing the risk of dehydration and low blood pressure. When taken with insulin or sulfonylureas, it may increase the risk of low blood sugar (hypoglycemia), and your doctor may need to adjust the dosage of these medications. There are also potential interactions with lithium. Always inform your doctor and pharmacist about all prescription, over-the-counter, herbal, and supplement products you are taking.

What precautions should be taken while taking ISTAVEL EMPA 10MG TAB?

Your doctor will likely monitor your kidney function and blood pressure regularly. It's important to maintain adequate fluid intake to prevent dehydration. Be aware of the symptoms of genital and urinary tract infections, and diabetic ketoacidosis. If you are having surgery (including dental surgery), planning a very low-carbohydrate diet, or experiencing severe illness with vomiting or diarrhea, your doctor may advise you to temporarily stop taking this medication. Additionally, foot care is important, and any new pain, tenderness, sores, or infections on your legs or feet should be reported to your doctor immediately due to a rare risk of lower limb amputation. Alcohol consumption may also affect blood sugar levels and should be discussed with your doctor.

What happens if a dose of ISTAVEL EMPA 10MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose (e.g., less than 12 hours until the next dose), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ISTAVEL EMPA 10MG TAB be stored?

Store ISTAVEL EMPA 10MG TAB in a closed container at room temperature, typically between 68°F to 77°F (20°C to 25°C). Keep it away from heat, moisture, and direct light. Ensure it is kept out of the reach of children and pets.