Criz M Tablet (10 Tab)

CRIZ M TABLET

CRIZ M TABLET is a combination medicine manufactured by Alkem Laboratories Ltd., primarily used to manage various allergic conditions and respiratory symptoms.

• Name:

  • Brand Name: Criz-M Tablet, CRIZ M Tablet

• Composition:

  • Each film-coated tablet contains:
    • Montelukast Sodium IP equivalent to Montelukast: 10 mg
    • Levocetirizine Hydrochloride IP: 5 mg

• Uses: CRIZ M TABLET is prescribed for the treatment and prevention of allergy symptoms and related respiratory conditions. It is effective for:

  • Allergic Rhinitis: Including seasonal (hay fever) and perennial allergies, alleviating symptoms such as runny nose, sneezing, watery eyes, itchy nose, and nasal congestion.
  • Asthma Management: Used as a maintenance therapy to manage symptoms of asthma, including coughing, wheezing, and difficulty breathing, by reducing airway inflammation. It is not for acute asthma attacks.
  • Chronic Urticaria: (Hives) – a skin rash characterized by red, itchy welts and swelling caused by allergic reactions.
  • Other allergic reactions causing itching, swelling, and inflammation.

• Dosage and Administration:

  • Typically, one tablet is taken once daily, usually in the evening.
  • It can be taken with or without food.
  • Swallow the tablet whole with a glass of water; do not cut, break, or chew it.
  • Follow the dosage and duration as prescribed by your doctor. Do not discontinue the medication abruptly, even if symptoms improve, to prevent recurrence.

• Side Effects: Most side effects are temporary and mild, resolving upon discontinuation of the medicine. However, consult your doctor if they persist or worsen.

  • Common Side Effects: Headache, tiredness/fatigue, dry mouth, sleepiness/drowsiness, nausea, diarrhea, vomiting, skin rash, blocked nose, upper respiratory tract infection, sore throat, fever, abdominal pain, dizziness, pharyngitis, increased appetite, UTI, coughing, emotional lability, and irritability.
  • Serious Side Effects (Rare): Blurred vision, severe skin rash, swelling of the face, lips, or throat, and difficulty breathing. Seek immediate medical attention if these occur.
  • Overdose symptoms: May include nausea, diarrhea, dry mouth, fatigue, headache, skin rash, sleepiness, vomiting, stomach pain, thirst, hyperactivity, agitation, excitation, and restlessness. Seek immediate medical attention in case of overdose.

• Precautions:

  • Kidney/Liver Disease: Use with caution in patients with kidney or liver disease. Inform your doctor about any existing conditions.
  • Pregnancy: Generally considered safe if prescribed, but it is recommended to consult a doctor before use.
  • Breastfeeding: Unsafe to use during breastfeeding as it may harm the baby.
  • Alcohol Consumption: Avoid alcohol as it may increase drowsiness and dizziness.
  • Driving/Operating Machinery: May cause dizziness or drowsiness; avoid activities requiring concentration if affected.
  • Acute Asthma Attacks: CRIZ M TABLET is not for treating acute or severe asthma attacks. Use appropriate rescue medication as advised by your doctor.
  • Drug Interactions: Inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions, especially with medicines for high blood pressure, heart failure, high cholesterol, blood thinners, anti-infectives, anti-diabetics, anti-asthmatics, pain killers, immunomodulatory medicines, or brain-related disorders.
  • Allergy Tests: Stop taking CRIZ M TABLET at least three days before an allergy test, as it can affect test results.
  • Neuropsychiatric Symptoms: Be vigilant for any changes in behavior or mood, such as anxiety or depression, and contact your doctor immediately if such events occur.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep the medicine below 30°C or at room temperature (20-25°C).
  • Protect from light and moisture.
  • Keep out of sight and reach of children and pets.

1. What is CRIZ M TABLET used for?

CRIZ M TABLET is primarily used to relieve and prevent symptoms associated with various allergic conditions in adults and adolescents aged 15 years or above. These conditions include allergic rhinitis (seasonal and perennial hay fever), chronic idiopathic urticaria (hives), and bronchial asthma. It helps alleviate symptoms such as a runny nose, sneezing, watery eyes, itching, congestion, and inflammation in the airways, making breathing easier.

2. How does CRIZ M TABLET work?

CRIZ M TABLET contains two active ingredients: Levocetirizine and Montelukast. Levocetirizine is an antihistamine that works by blocking the action of histamine, a chemical released by the body during allergic reactions that causes symptoms like itching, sneezing, and a runny nose. Montelukast is a leukotriene antagonist that blocks certain substances called leukotrienes, which are responsible for inflammation in the airways and nose during an allergic reaction. Together, these ingredients reduce allergic symptoms and inflammation.

3. What is the usual dosage of CRIZ M TABLET?

The usual dosage for CRIZ M TABLET is one tablet taken once daily, with or without food, as prescribed by your doctor. It is often recommended to take it in the evening. Always follow your doctor's instructions regarding the dose and duration of treatment.

4. What are the possible side effects of CRIZ M TABLET?

Common side effects of CRIZ M TABLET may include headache, tiredness, fatigue, sleepiness, dry mouth, nausea, diarrhea, vomiting, skin rash, blocked nose, and dizziness. Other reported side effects include upper respiratory tract infection, sore throat, fever, abdominal pain, and increased liver enzymes. If you experience any severe or persistent side effects, it is important to consult your doctor.

5. Is CRIZ M TABLET safe during pregnancy or breastfeeding?

During pregnancy, CRIZ M TABLET is generally considered safe, but it is highly recommended to consult your doctor before taking it to ensure it is appropriate for your specific condition.

During breastfeeding, CRIZ M TABLET is generally considered unsafe. A component of the medicine (Levocetirizine) can pass into breast milk and may cause drowsiness in the nursing infant. Therefore, it is advisable to avoid this medication while breastfeeding unless explicitly prescribed by your doctor after weighing the potential risks and benefits.

6. Can CRIZ M TABLET be taken with other medications?

CRIZ M TABLET can interact with certain medications. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take. Some medications that may interact include sedatives or tranquilizers (e.g., diazepam, lorazepam), antidepressants (e.g., fluoxetine, sertraline), antifungal medications (e.g., ketoconazole, fluconazole), gemfibrozil, certain CNS depressants (e.g., phenobarbital), phenytoin, rifampicin, ritonavir, and theophylline.

7. What precautions should I take while using CRIZ M TABLET?

Several precautions should be observed when taking CRIZ M TABLET:

• Alcohol: Avoid consuming alcohol as it can increase drowsiness and dizziness.
• Driving and Machinery: This medicine may cause dizziness or sleepiness, so exercise caution when driving or operating machinery until you know how it affects you.
• Medical Conditions: Inform your doctor if you have kidney or liver disease, as dosage adjustments may be necessary.
• Allergies: Do not take CRIZ M TABLET if you are allergic to levocetirizine, montelukast, or any of its other ingredients.
• Neuropsychiatric Symptoms: Be vigilant for any mood or behavior changes, such as anxiety, aggression, or suicidal thoughts, and report them to your doctor immediately.
• Allergy Tests: Stop taking CRIZ M TABLET at least three days before an allergy test, as it can affect the test results.
• Elderly Patients: Use with caution in elderly patients due to a potentially increased risk of side effects.

8. What happens if a dose of CRIZ M TABLET is missed?

If you miss a dose of CRIZ M TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

9. How should CRIZ M TABLET be stored?

CRIZ M TABLET should be stored in a cool and dry place, typically below 25°C or 30°C. Protect it from direct sunlight and moisture. Always keep the medicine out of the sight and reach of children and pets.

10. Can CRIZ M TABLET be used for acute asthma attacks?

No, CRIZ M TABLET is not intended for the treatment of acute or severe asthma attacks. It is a preventive medication used for long-term management of asthma symptoms. For acute asthma exacerbations, you should use your prescribed rescue medication, such as an inhaler.