Crema Gel 30 Gm

CREMA GEL 30 GM by ABBOTT INDIA LIMITED

Name

Brand Name: Crema Gel (also referred to as Cremagel) Common Name: Diltiazem Topical Gel

Composition

Crema Gel 30 GM contains Diltiazem 2% w/w as its active ingredient. Diltiazem is a calcium channel blocker.

Uses

Crema Gel is primarily prescribed for the treatment of anal fissures, which are small tears in the lining of the anus. It helps to promote healing of the tear and reduces associated symptoms such as pain, irritation, and itching. Diltiazem works by relaxing the anal sphincter muscles, thereby reducing anal pressure and increasing blood flow to the affected area, which aids in the healing process.

Dosage and Administration

Crema Gel is for external use only. It is typically applied twice daily, usually in the morning and evening, or as directed by a healthcare professional. Before application, the affected anal area should be gently cleaned and thoroughly dried. A small amount of gel should be applied to the anus using a finger covering, such as cling film or a disposable glove. Wash hands thoroughly before and after application.

Side Effects

Common side effects include:

• Application site reactions (burning sensation, itching, redness, irritation).
• Headache.
• Dizziness or lightheadedness.

Less common or serious side effects can include rectal bleeding, severe dizziness or fainting, fast/pounding heartbeat, sweating, chest pain, blurred vision, dark urine, bluish lips/skin/nails, or seizures. Allergic reactions (e.g., skin rash, swelling of face/lips/throat, difficulty breathing) may also occur.

Precautions

• Avoid contact with eyes, mouth, nose, ears, or vagina. In case of accidental contact, rinse thoroughly with water.
• Inform your doctor if you have known allergies to diltiazem or any other ingredients of Crema Gel.
• Consult a doctor if you are pregnant or breastfeeding.
• Crema Gel may cause lightheadedness or dizziness; therefore, it is advisable to avoid driving or operating machinery until you are mentally alert.
• Inform your doctor about any pre-existing heart conditions, low blood pressure, anemia, increased pressure in the brain, or severe dehydration.
• Caution is advised for patients with liver or kidney impairment; consult your doctor.
• Inform your doctor about all other medicines you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
• Do not cover the treated area with a bandage unless specifically instructed by your doctor.
• The safety and efficacy in pediatric patients (below 18 years) have not been established.

Storage

Store Crema Gel in a cool, dry place, away from direct sunlight and moisture, at a temperature between 10ºC to 25ºC or below 30ºC. Keep it out of reach and sight of children.

CREMA GEL 30 GM by ABBOTT INDIA LIMITED: Frequently Asked Questions

What is CREMA GEL 30 GM used for?

CREMA GEL 30 GM is primarily used for the treatment of anal fissures, which are small tears or cuts in the lining of the anus. It helps to promote healing, reduce pain, irritation, and itching associated with this condition.

How does CREMA GEL 30 GM work?

The active ingredient in CREMA GEL 30 GM is Diltiazem hydrochloride, which is a calcium channel blocker. It works by relaxing the smooth muscles around the anus (anal sphincter), which in turn reduces anal pressure and increases blood flow to the affected area, thereby aiding in the healing process.

What is the usual dosage for CREMA GEL 30 GM?

The recommended daily dose of CREMA GEL 30 GM is typically applied topically around and gently inside the anus once or twice a day, or as directed by your doctor. The specific dosage and duration of treatment may vary based on the severity of the condition and individual response.

What are the possible side effects of CREMA GEL 30 GM?

Common side effects include local skin reactions at the application site such as itching, burning, and redness. Other reported side effects can include headache and dizziness. Less common side effects may include rectal bleeding, soreness, and fatigue. These side effects are usually mild and resolve on their own. If they persist or worsen, consult your healthcare provider.

Is CREMA GEL 30 GM safe during pregnancy or breastfeeding?

There is limited information regarding the safety of CREMA GEL 30 GM during pregnancy. It should be used during pregnancy only if considered necessary by a physician. It is generally not recommended during breastfeeding, as it is unknown whether diltiazem is excreted in human milk and there is a potential risk of adverse effects on the nursing infant. It is advisable to consult your doctor before using this medicine if you are pregnant or breastfeeding.

Can CREMA GEL 30 GM be taken with other medications?

CREMA GEL 30 GM can interact with certain medications, even though it is applied topically. It's important to inform your doctor about all medications, supplements, and herbal products you are taking. Interactions may occur with asthma medications (e.g., Salmeterol, Formoterol, Budesonide), pain relievers (e.g., Aspirin, Naproxen, Ibuprofen), blood pressure medications (e.g., Atenolol, Metoprolol), allergy medications (e.g., Diphenhydramine, Loratadine), certain anesthetics (e.g., Lidocaine), medications for heart failure (e.g., Digoxin), and anxiety medications (e.g., Alprazolam).

What precautions should be taken while using CREMA GEL 30 GM?

CREMA GEL 30 GM is for external use only. Avoid contact with your eyes, mouth, nose, ears, and vagina. Wash your hands thoroughly before and after application. If accidental contact occurs with eyes, rinse immediately with plenty of water. Inform your doctor if you have any pre-existing heart, kidney, or liver conditions, low blood pressure, anemia, increased pressure in the brain, or severe dehydration. Also, alert your doctor if you have any known allergies to diltiazem or other ingredients in the gel. It is advisable to limit or avoid alcohol consumption while using this gel, as it may increase the risk of side effects like dizziness and lightheadedness.

What happens if a dose of CREMA GEL 30 GM is missed?

If you forget to apply CREMA GEL 30 GM as per the prescribed dosage, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular dosing schedule. Do not apply a double amount to compensate for a missed dose.

How should CREMA GEL 30 GM be stored?

CREMA GEL 30 GM should be stored in a cool and dry place, ideally below 30°C. Keep it away from direct sunlight and heat, and ensure it is out of the reach and sight of children.