Uniprogestin 500mg Inj

UNIPROGESTIN 500MG INJ

UNIPROGESTIN 500MG INJ, manufactured by Torrent Pharmaceuticals Ltd, is a medication primarily used in obstetrics.

• Name:
  • Brand Name: UNIPROGESTIN 500MG INJ (B-GYNE is associated with the manufacturer, Torrent Pharma Ltd, but not a distinct brand name for this specific product)
  • Common Name: Hydroxyprogesterone Injection
• Composition:
  • Active Ingredient: Hydroxyprogesterone (500mg)
• Uses:
  • UNIPROGESTIN 500MG INJ is a synthetic form of the female hormone progesterone. It is primarily prescribed to prevent premature labor in pregnant women who have a history of preterm delivery.
  • It helps to lower the risk of giving birth too early (preterm birth) and also aids in preventing miscarriage.
  • It thickens the lining of the uterus and helps create a suitable environment for fetal growth.
• Dosage and Administration:
  • This injection is administered by or under the direct supervision of a healthcare professional.
  • Typically, it is given weekly, usually starting between 16 and 20 weeks of pregnancy and continuing through week 37, or until delivery.
• Side Effects:
  • Common: Local reactions at the injection site (pain, swelling, itching, redness, hard bump), nausea, itching, diarrhea, rash, headache, dizziness, and fatigue.
  • Serious: May affect blood sugar levels, potential liver problems (yellowing of eyes/skin, dark urine, stomach pain), chest pain, blood clot formation, severe headache, slurred speech, shortness of breath, and vision changes.
• Precautions:
  • Not recommended for women pregnant with more than one baby (twins, triplets, etc.) or to stop active premature labor.
  • Contraindicated in individuals with allergies to its ingredients, liver issues (including liver cancer), breast cancer or other hormone-sensitive cancers, undiagnosed abnormal vaginal bleeding, history of blood clot disorders, jaundice during pregnancy, or uncontrolled high blood pressure.
  • Caution is advised for patients with asthma, kidney or heart problems, diabetes/pre-diabetes, epilepsy, or migraine. Regular blood sugar monitoring may be necessary.
• Storage:
  • Store in a cool and dry place, away from direct sunlight.
  • Typically, store at temperatures between 10ºC and 25ºC or below 30ºC.
  • Keep out of sight and reach of children.

Here are frequently asked questions about UNIPROGESTIN 500MG INJ (B-GYNE.) by TORRENT PHARMA LTD, containing Hydroxyprogesterone:

What is UNIPROGESTIN 500MG INJ used for?

UNIPROGESTIN 500MG INJ is primarily used to prevent premature labor, reduce the risk of preterm birth, and prevent miscarriage in pregnant women who have a history of delivering a baby too early. It is generally prescribed for women with a singleton pregnancy.

How does UNIPROGESTIN 500MG INJ work?

This medicine contains Hydroxyprogesterone, which is a synthetic progestin (female hormone). It works by modulating the immune response in pregnant women to help prevent the rejection of the embryo and allow its proper attachment to the uterus. It also helps to thicken the uterine lining and prevent contractions that could lead to premature labor. The exact mechanism by which it prevents premature birth is still not fully understood.

What is the usual dosage of UNIPROGESTIN 500MG INJ?

UNIPROGESTIN 500MG INJ is administered as an injection by a doctor or trained healthcare professional. The specific dosage and duration of treatment are determined by your doctor based on your individual medical condition. Typically, it is given weekly, starting between 16 and 20 weeks of pregnancy and continuing until week 37, or until delivery, whichever comes first.

What are the possible side effects of UNIPROGESTIN 500MG INJ?

Common side effects can include pain, swelling, itching, redness, bumps, or a rash at the injection site. Other common side effects may include nausea, vomiting, diarrhea, headache, dizziness, fatigue, and fever. More serious but less common side effects can involve blood clots, allergic reactions (like hives or swelling of the face, lips, tongue, or throat), fluid retention, increased blood pressure, changes in blood sugar levels (worsening diabetes), depression, and vision abnormalities. You should inform your doctor if any side effects persist or worsen, or if you experience symptoms like yellowing of the eyes or skin, dark urine, or stomach pain.

Is UNIPROGESTIN 500MG INJ safe during pregnancy or breastfeeding?

During Pregnancy: UNIPROGESTIN 500MG INJ is indicated for use during pregnancy to prevent preterm birth in specific cases. While some sources indicate it is generally considered safe if prescribed by a doctor, especially based on animal studies showing minimal adverse effects, human studies are limited. It is important to note that it is typically not recommended for use in the first trimester or to stop active premature labor. Your doctor will weigh the benefits against potential risks. During Breastfeeding: Information regarding breastfeeding is conflicting. Some sources suggest it is safe if prescribed, stating that the drug does not pass into breast milk in significant amounts. However, other sources advise caution or state it is not recommended as it may affect the infant, and recommend consulting a doctor for a safer alternative or waiting at least 6 weeks postpartum. Always consult your doctor before using this medicine while breastfeeding.

Can UNIPROGESTIN 500MG INJ be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. UNIPROGESTIN 500MG INJ can interact with certain medications. For example, some drugs that affect liver enzymes (like phenytoin, carbamazepine, ketoconazole) can alter its effectiveness or increase side effects. It may also affect blood glucose levels, requiring adjustments to anti-diabetic medications. Using it with anticoagulants (blood thinners) may increase the risk of bleeding. The effects of some other medicines, such as cyclosporine and paracetamol, may also be influenced.

What precautions should be taken while using UNIPROGESTIN 500MG INJ?

You should not receive UNIPROGESTIN 500MG INJ if you have a history of blood clots or blood clotting disorders, liver problems (including liver tumors or active liver disease), breast cancer or other hormone-sensitive cancers, uncontrolled high blood pressure, undiagnosed abnormal vaginal bleeding unrelated to pregnancy, or cholestatic jaundice of pregnancy. Caution is advised if you have conditions such as asthma, epilepsy, diabetes, pre-eclampsia, heart or kidney problems, or a history of depression. Your doctor should be informed of any such conditions.

What happens if a dose of UNIPROGESTIN 500MG INJ is missed?

Since UNIPROGESTIN 500MG INJ is administered by a healthcare professional, it is unlikely that you will miss a dose. However, if you believe a dose has been missed, you should contact your doctor or nurse immediately for further instructions.

How should UNIPROGESTIN 500MG INJ be stored?

UNIPROGESTIN 500MG INJ should be stored in a cool, dry place, away from direct sunlight, at temperatures typically between 10ºC and 25ºC or below 30ºC. The vial should be stored upright in its box and protected from light. After the first use, the medicine should be used within 5 weeks. It is important to keep this medication out of the sight and reach of children.