Shrintel Mx 25/40mg Tab

Here is the detailed product description for SHRINTEL MX 25/40MG TAB:

SHRINTEL MX 25/40MG TAB

• Name: Shrintel MX 25 Tablet ER (Common Name), SHRINTEL MX 25/40MG TAB (Brand Name)
• Composition: Each tablet contains Telmisartan 40mg and Metoprolol Succinate 25mg.
• Uses:
  • Treatment of Hypertension (high blood pressure).
  • Helps in preventing future heart attacks and strokes by lowering blood pressure.
  • Improves the chances of survival in patients with heart attacks when treated early.
  • Used to manage heart-related complications.
  • Indicated for individuals aged 55 years or older who are at high risk of major cardiovascular events and cannot take ACE inhibitors.
• Dosage and Administration:
  • Take as advised by your doctor, usually with food at a fixed time each day to maintain consistent medicine levels in the blood.
  • Swallow the tablet whole. Do not chew, crush, or break it.
  • Do not stop taking the medication suddenly without consulting your doctor, as this can worsen your condition.
• Side Effects:
  • Common: Headache, weakness, dizziness, cold extremities, slow heart rate, increased potassium level in blood, decreased blood pressure, orthostatic hypotension (sudden lowering of blood pressure on standing), breathlessness, abdominal pain, nausea, vomiting, fatigue, stomach pain.
• Precautions:
  • Alcohol: Unsafe to consume alcohol as it may increase side effects like dizziness.
  • Pregnancy: Unsafe for use during pregnancy, especially in the second and third trimesters, due to definite evidence of risk to the developing baby.
  • Breastfeeding: Probably unsafe or not recommended; consult your doctor.
  • Driving: May decrease alertness, affect vision, or cause dizziness/sleepiness; avoid driving or operating heavy machinery until you know how it affects you.
  • Kidney/Liver: Use with caution in patients with kidney or liver disease. Regular monitoring of kidney function may be advised.
  • Diet: Advised to avoid potassium-rich foods and supplements.
  • Drug Interactions: Inform your doctor about all other medicines, especially those for high blood pressure or heart conditions. Ibuprofen and certain other painkillers may increase the risk of kidney problems and reduce the medication's effectiveness.
  • Monitoring: Regular monitoring of blood pressure, blood sugar level, kidney functioning, urea, or electrolytes level may be required during treatment.
• Storage:
  • Store below 25°C or 30°C.
  • Keep away from moisture and heat.
  • Store in its original container, tightly closed.
  • Keep out of sight and reach of children.

SHRINTEL MX 25/40MG TAB by SHREEDA PHARMACEUTICALS DIV is a combination medication containing Metoprolol Succinate and Amlodipine. This medicine is primarily used to manage cardiovascular conditions.

1. What is SHRINTEL MX used for?

SHRINTEL MX, which contains Metoprolol Succinate and Amlodipine, is prescribed to treat high blood pressure (hypertension) and chest pain (angina). It may also be used in the management of certain chronic heart conditions, including heart failure.

2. How does SHRINTEL MX work?

SHRINTEL MX combines two active ingredients with different mechanisms to effectively manage blood pressure and heart conditions.

• Metoprolol Succinate is a beta-blocker that works by selectively blocking beta-1 adrenergic receptors in the heart. This action reduces heart rate, decreases the force of heart contractions, and lowers cardiac output, thereby reducing blood pressure and the heart's workload.
• Amlodipine is a calcium channel blocker that relaxes and widens blood vessels by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle cells. This leads to a reduction in peripheral vascular resistance, which lowers blood pressure and improves blood flow.

3. What is the usual dosage for SHRINTEL MX?

The specific dosage for SHRINTEL MX, including the 25/40MG strengths, should be determined and prescribed by a healthcare professional. Typically, combination tablets containing Metoprolol Succinate and Amlodipine are taken once daily. Important note: While Metoprolol Succinate 25mg is a common dosage, Amlodipine 40mg is an unusually high dose, as the maximum recommended daily dose for Amlodipine is generally 10mg in adults. It is crucial to confirm the exact prescribed dosage and formulation with your doctor or pharmacist to ensure safety and effectiveness.

4. What are the possible side effects of SHRINTEL MX?

Common side effects of this medication may include tiredness (fatigue), dizziness, headache, nausea, abdominal pain, sleepiness, and swelling of the ankles or legs (edema). Other possible effects include slow heart rate, flushing (a sensation of warmth), heart palpitations, constipation, and diarrhea. Serious side effects can occur, such as dangerously low blood pressure, severe dizziness, or worsening chest pain, especially when starting the medication or increasing the dose. If you experience any persistent, bothersome, or severe side effects, you should consult your doctor.

5. Is SHRINTEL MX safe during pregnancy or breastfeeding?

• Pregnancy: Amlodipine can generally be used during pregnancy and is not thought to be harmful, although information is limited. Metoprolol can be taken during pregnancy, but it may sometimes affect the baby's growth, potentially requiring additional monitoring. If used in late pregnancy, Metoprolol might cause symptoms like slowed heart rate or low blood sugar in the newborn. It is essential to discuss your medication with your doctor if you are pregnant or planning a pregnancy.
• Breastfeeding: Amlodipine is considered safe during breastfeeding, as minimal amounts transfer into breast milk, and no adverse effects have been reported in breastfed infants. Metoprolol also passes into breast milk in very small amounts and has not been known to cause side effects in breastfed babies. If you observe unusual sleepiness, poor feeding, or pale skin in your baby, contact your doctor immediately.

6. Can SHRINTEL MX be taken with other medications?

It is critical to inform your doctor and pharmacist about all prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are currently taking or intend to take.

• Amlodipine can interact with certain antifungals (e.g., clarithromycin, erythromycin, itraconazole, ketoconazole), some immunosuppressants (e.g., cyclosporine, tacrolimus), and statins (e.g., simvastatin, lovastatin), which can increase the risk of side effects. Combining amlodipine with phosphodiesterase-5 inhibitors (e.g., sildenafil) can lead to significant drops in blood pressure. Consuming grapefruit or grapefruit juice can also increase amlodipine levels and worsen side effects.
• Metoprolol Succinate interactions include additive effects when taken with other medications that slow heart rate or lower blood pressure. Specifically, other calcium channel blockers, such as amlodipine itself, can further slow heart rate. The combination of Amlodipine and Metoprolol Succinate is contraindicated in patients with conditions such as severe bradycardia (slow heartbeat) or heart block greater than first-degree.

7. What precautions should be taken?

Do not stop taking SHRINTEL MX abruptly without consulting your doctor, as this could lead to a worsening of your condition. Regular check-ups with your doctor are important to monitor your blood pressure and overall progress. Inform your doctor if you have liver problems, as dosage adjustments may be necessary. Exercise caution if you have certain heart conditions, such as severe aortic stenosis, or very low blood pressure, as Amlodipine can potentially worsen these conditions. This medication may cause dizziness or drowsiness; therefore, avoid driving or operating heavy machinery until you understand how it affects you. Discuss alcohol consumption with your doctor, as it might increase the risk of certain side effects when taken with Amlodipine. Additionally, inform your doctor if you have asthma or other lung diseases, severe blood circulation problems, or diabetes.

8. What happens if a dose of SHRINTEL MX is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to compensate for a missed one. Missing doses can cause your blood pressure or chest pain to worsen, which could lead to serious health issues like a stroke or heart attack.

9. How should SHRINTEL MX be stored?

Store SHRINTEL MX in its original packaging, with the container tightly closed. Keep the medicine at room temperature, typically between 68°F and 77°F (20°C and 25°C). It should be protected from light, moisture, and extreme temperatures. Always ensure the medication is kept out of the reach of children and pets. Avoid storing it in moist areas, such as bathrooms.