Glitaris M 15 Tablet (10 Tab)

GLITARIS M 15 TABLET

GLITARIS M 15 TABLET is a medication manufactured by ERIS LIFESCIENCES LIMITED, designed for the management of Type 2 Diabetes Mellitus.

• Name: Glitaris M 15 Tablet (Brand Name); also referred to as Glitaris M 15 Tablet SR.
• Composition: Each tablet contains Pioglitazone 15 mg and Metformin 500 mg.
• Uses: GLITARIS M 15 TABLET is primarily used in adults for the treatment of Type 2 Diabetes Mellitus. It works by lowering blood sugar levels through two mechanisms: Pioglitazone increases the body's sensitivity to insulin, while Metformin decreases glucose production by the liver and increases its uptake by cells. This helps improve blood sugar control and prevent long-term diabetic complications such as kidney damage, vision loss, nerve damage, and diabetic foot ulcers.
• Dosage and Administration: This medicine should be taken orally as a whole tablet with sufficient water, usually once or twice daily with meals to minimize gastrointestinal upset. Do not crush, chew, or break the tablet. The exact dosage and duration will be prescribed by a healthcare professional based on individual needs and blood glucose monitoring. It should not be discontinued without consulting a doctor.
• Side Effects:
  • Common: Stomach aches, nausea, vomiting, diarrhea, loss of appetite, localized swelling (oedema), weight gain, headaches, upper respiratory tract infections, muscle pain, and taste disturbances.
  • Serious: Rare but serious side effects include lactic acidosis (symptoms like severe vomiting, rapid breathing, muscle cramps, extreme tiredness), severe allergic reactions, liver inflammation (yellowing of skin/eyes), and hypoglycemia (especially when combined with insulin).
• Precautions: GLITARIS M 15 TABLET is contraindicated in patients with Type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, heart failure (NYHA Class III or IV), bladder cancer, or a history of allergic reactions to its components. Caution is advised in elderly patients. Alcohol consumption should be avoided due to an increased risk of lactic acidosis. Inform your doctor about existing conditions like pancreatitis, low vitamin B12 levels, or if you are pregnant or breastfeeding, as the medicine is generally not recommended during these periods. It may interact with other medications, including certain pain relievers, blood pressure medications, and iodinated contrast agents for X-rays.
• Storage: Store in a cool and dry place, away from direct sunlight and moisture. Keep out of sight and reach of children, ideally at room temperature (between 10ºC and 25ºC or below 30ºC).

What is GLITARIS M 15 TABLET used for?

GLITARIS M 15 TABLET is prescribed for adults to treat Type 2 Diabetes Mellitus. It is typically used when diet and exercise alone, or treatment with a single antidiabetic medication (like metformin or pioglitazone), are not sufficient to control blood sugar levels. This medication helps improve blood sugar control, enhance the body's sensitivity to insulin, and reduce the risk of serious diabetes complications such as eyesight loss, kidney damage, nerve damage, and diabetic foot ulcers.

How does GLITARIS M 15 TABLET work?

GLITARIS M 15 TABLET contains two active ingredients: Pioglitazone and Metformin. Pioglitazone belongs to the thiazolidinedione class and works by activating cellular switches (PPAR) to help body cells absorb glucose from the blood for energy production, thereby increasing insulin sensitivity. Metformin, a biguanide, reduces the amount of glucose produced by the liver, decreases glucose absorption from the intestines, and improves the body's utilization of glucose by cells, also enhancing insulin sensitivity. Together, these components provide a dual action to effectively manage blood sugar levels.

What is the usual dosage of GLITARIS M 15 TABLET?

The dosage of GLITARIS M 15 TABLET should be strictly as advised by your doctor, as it can vary based on your condition and response to treatment. It is generally recommended to take this medicine with food to minimize stomach upset. The tablet should be swallowed whole with water and not crushed, chewed, or broken.

What are the possible side effects of GLITARIS M 15 TABLET?

Common side effects can include stomach aches, nausea, vomiting, diarrhea, loss of appetite, localized swelling (edema), weight gain, headaches, upper respiratory tract infections, numbness, and taste disturbances. These usually do not require medical attention but consult your doctor if they persist. More serious, but rare, side effects can include lactic acidosis (symptoms like severe vomiting, rapid breathing, muscle pain, and severe tiredness), fluid retention, fractures, and vision problems. Hypoglycemia (low blood sugar) can also occur, especially if doses are missed, alcohol is consumed, or with concurrent use of other diabetes medications. Prolonged use may also lead to a decrease in thyroid-stimulating hormone (TSH) and Vitamin B12 deficiency.

Is GLITARIS M 15 TABLET safe during pregnancy or breastfeeding?

GLITARIS M 15 TABLET is generally not recommended during pregnancy as there is limited information on its effects in pregnant women, and animal studies have shown potential harm to the developing baby. Similarly, it is not recommended for use while breastfeeding as it may pass into breast milk. Always consult your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

Can GLITARIS M 15 TABLET be taken with other medications?

It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions. GLITARIS M 15 TABLET should not be used if you are undergoing an X-ray involving iodinated contrast agents. Caution is advised when taken with other diabetes medications (e.g., insulin), pain relievers (e.g., ibuprofen, aspirin), blood pressure medications, certain cholesterol-lowering drugs (e.g., gemfibrozil), corticosteroids, and some heart medications, as these can affect its efficacy or increase the risk of side effects like very low blood sugar or lactic acidosis.

What precautions should be taken while taking GLITARIS M 15 TABLET?

Before starting this medicine, inform your doctor if you have a history of heart failure, kidney disease, liver disease, bladder cancer, pancreatitis, or low vitamin B12 levels. It is not suitable for individuals with Type 1 diabetes or diabetic ketoacidosis. Avoid excessive alcohol consumption as it significantly increases the risk of lactic acidosis and low blood sugar. Regular monitoring of blood sugar, liver function, and kidney function is recommended during treatment. Elderly patients should use this medication with caution due to an increased risk of certain side effects. Do not discontinue the medicine without consulting your doctor.

What happens if a dose of GLITARIS M 15 TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can lead to low blood sugar. Missing doses can result in uncontrolled high blood sugar levels.

How should GLITARIS M 15 TABLET be stored?

GLITARIS M 15 TABLET should be stored in a cool and dry place, away from direct sunlight. It should be kept out of sight and reach of children and pets. The medicine typically requires storage at temperatures below 30ºC or between 10ºC to 25ºC.