DEPLATT AV 20 MG CAPSULE

Name

Brand Name: DEPLATT AV 20 MG CAPSULE Common Name: Atorvastatin + Clopidogrel (combination medicine)

Composition

Each capsule contains:

• Atorvastatin: 20 mg
• Clopidogrel: 75 mg

Uses

DEPLATT AV 20 MG CAPSULE is used to prevent heart attacks, strokes, and other cardiovascular events. It is prescribed for:

• Reducing elevated levels of "bad" cholesterol (LDL) and triglycerides.
• Increasing "good" cholesterol (HDL) levels.
• Preventing blood clot formation in high-risk patients, including those with a history of heart attack, stroke, unstable angina, or peripheral arterial disease.

Dosage and Administration

The recommended dosage is once daily, or as directed by a physician. The capsule should be swallowed whole with a glass of water and should not be crushed, chewed, or opened. It can be taken with or without food, but taking it with food may help prevent stomach upset. It is important to take the medicine regularly at the same time each day to maintain consistent levels. Do not stop taking this medication without consulting your doctor.

Side Effects

Common side effects include:

• Headache
• Dizziness
• Nausea
• Muscle pain (myalgia)
• Joint pain
• Diarrhea
• Upset stomach/Indigestion
• Cold-like symptoms

Serious side effects can include:

• Liver damage (signs like yellowing of skin/eyes, jaundice)
• Severe or unusual bleeding or bruising
• Allergic reactions (skin rash, itching, difficulty breathing, swelling of face/lips/tongue)
• Muscle problems like myopathy and rhabdomyolysis

Precautions

• Pregnancy and Breastfeeding: Contraindicated in pregnant or breastfeeding women.
• Liver Disease: Not recommended for patients with active liver disease or unexplained persistent elevations of liver enzymes. Use with caution in patients with a history of liver disease.
• Bleeding Disorders: Contraindicated in patients with active bleeding (e.g., from an ulcer or in the brain) or a history of bleeding disorders, as it increases the risk of bleeding.
• Alcohol: Avoid alcohol consumption as it can increase the risk of liver damage and raise triglyceride levels.
• Grapefruit Juice: Avoid grapefruit juice as it may lead to unwanted interactions.
• Surgery: Inform your doctor if you have any scheduled surgery, as the medication may need to be stopped temporarily due to increased bleeding risk.
• Drug Interactions: Inform your doctor about all medications and supplements you are taking, especially immune suppressants (cyclosporine), certain antibiotics (rifampin, clarithromycin), anti-HIV drugs, antifungals (itraconazole), and other blood thinners (aspirin, warfarin), as these can interact with DEPLATT AV 20.

Storage

Store in a cool and dry place below 30°C, protected from moisture, sunlight, and heat. Keep out of sight and reach of children.

What is DEPLATT AV 20 CAPSULE used for?

DEPLATT AV 20 CAPSULE is a combination medication primarily used to reduce the risk of serious cardiovascular events such as heart attacks, strokes, and other heart-related complications like angina, heart failure, or the need for revascularization procedures. It is also prescribed to lower elevated "bad" cholesterol (LDL) and triglyceride levels in patients when diet and lifestyle changes alone have not been sufficient.

How does DEPLATT AV 20 CAPSULE work?

This medicine contains two active ingredients: Atorvastatin and Clopidogrel. Atorvastatin is an HMG-CoA reductase inhibitor that works by blocking an enzyme in the liver responsible for producing cholesterol. This action lowers "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL). Clopidogrel is an antiplatelet agent (blood thinner) that prevents platelets from clumping together, thereby reducing the formation of harmful blood clots in the arteries. Together, these actions help maintain smooth blood flow and protect against plaque buildup and clot-related complications.

What is the usual dosage for DEPLATT AV 20 CAPSULE?

DEPLATT AV 20 CAPSULE is typically taken orally once a day. It is recommended to take it with food to minimize stomach upset and at approximately the same time each day to ensure consistent levels in your body. The specific dose and duration of treatment will be determined by your doctor based on your medical condition and response to therapy. It is crucial not to stop taking this medication without consulting your doctor, even if you feel better, as premature discontinuation can increase the risk of cardiovascular events.

What are the possible side effects of DEPLATT AV 20 CAPSULE?

Common side effects may include headache, dizziness, nausea, stomach pain, diarrhea, indigestion, muscle pain, and joint pain. More serious, though rare, side effects can include unexpected or unusual bleeding or bruising, signs of liver problems (such as yellowing of the skin or eyes), or severe allergic reactions. You should inform your doctor if you experience any persistent or concerning symptoms.

Is DEPLATT AV 20 CAPSULE safe during pregnancy or breastfeeding?

DEPLATT AV 20 CAPSULE is generally not recommended during pregnancy and is considered unsafe as Atorvastatin, one of its components, may harm the developing fetus. It is also not recommended for use by breastfeeding women, as the components may pass into breast milk. If you are pregnant, planning to conceive, or breastfeeding, consult your doctor for alternative treatments.

Can DEPLATT AV 20 CAPSULE be taken with other medications?

DEPLATT AV 20 CAPSULE can interact with several other medications. Concomitant use with other blood thinners like warfarin can increase the risk of bleeding. Certain antibiotics (e.g., clarithromycin, rifampin), antifungals (e.g., ketoconazole, itraconazole), and immunosuppressants (e.g., cyclosporine) can affect the levels or effectiveness of Atorvastatin. Some proton pump inhibitors (e.g., omeprazole) may reduce the effectiveness of Clopidogrel. It's essential to inform your doctor about all medicines, including over-the-counter drugs, vitamins, and supplements, you are taking to avoid potential interactions.

What precautions should be taken while on DEPLATT AV 20 CAPSULE?

Several precautions should be observed while taking DEPLATT AV 20 CAPSULE. Avoid consuming alcohol and grapefruit juice, as they can lead to unwanted interactions and increase the risk of side effects like liver damage or increased triglyceride levels. Exercise caution with activities that may cause injury due to the increased risk of bleeding. Inform your doctor if you have liver or kidney disease, diabetes, bleeding disorders, or a history of muscle problems. Regular monitoring of cholesterol and liver function tests may be required. Notify your doctor if you experience any unusual bruising, bleeding, or muscle pain. Also, inform your healthcare provider that you are taking this medication before any surgical or dental procedures.

What happens if a dose of DEPLATT AV 20 CAPSULE is missed?

If you miss a dose of DEPLATT AV 20 CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this may increase the risk of side effects.

How should DEPLATT AV 20 CAPSULE be stored?

DEPLATT AV 20 CAPSULE should be stored in a cool and dry place, below 30°C, protected from moisture and direct sunlight. Keep the medicine out of sight and reach of children and pets.