Olvance H 40mg Tab

OLVANCE H 40MG TABLET

Olvance H 40mg Tablet is a combination medication primarily used for the management of high blood pressure (hypertension). It is manufactured by Sun Pharmaceutical Industries Ltd.

• Composition

  • Olmesartan Medoxomil (40 mg): An angiotensin II receptor blocker (ARB) that helps relax and widen blood vessels.
  • Hydrochlorothiazide (12.5 mg): A diuretic (water pill) that increases urine output, helping the body eliminate excess salt and water.

• Uses

  • Management of essential hypertension (high blood pressure).
  • Reduces the risk of heart-related complications such as heart attacks, strokes, and kidney failure.
  • Can be used in combination with other antihypertensive agents or for patients requiring multiple medications to achieve blood pressure goals.

• Dosage and Administration

  • Typically, one tablet is taken once daily, as prescribed by a doctor.
  • Can be taken with or without food.
  • Swallow the tablet whole; do not crush or chew.
  • It is advisable to take the medicine at the same time each day. Due to its diuretic effect, avoid taking it close to bedtime to prevent frequent urination during the night. Do not stop the medication abruptly without consulting a doctor.

• Side Effects

  • Common: Dizziness, headache, nausea, diarrhea, loss of appetite, rash, weakness, fatigue, chest pain, swelling (edema), upper respiratory tract infection, increased uric acid levels, and increased blood urea.
  • Serious (seek immediate medical attention): Severe allergic reactions (e.g., swelling of face/mouth/throat), significant hypotension (fainting/lightheadedness), severe persistent diarrhea, signs of electrolyte imbalance (e.g., extreme thirst, muscle pain, rapid heart rate), or vision changes.

• Precautions

  • Avoid use during the second and third trimesters of pregnancy due to potential harm to the fetus. Consult a doctor if breastfeeding.
  • Use with caution in patients with kidney or liver disease, diabetes, or severe congestive heart failure.
  • Alcohol consumption should be limited as it may increase dizziness and further lower blood pressure.
  • Driving or operating heavy machinery should be avoided if dizziness occurs.
  • Inform your doctor about all other medications, supplements, or herbal products being taken to prevent potential drug interactions, especially with potassium-sparing diuretics, NSAIDs, lithium, or other blood pressure medications. Regular monitoring of kidney function, electrolytes, and blood pressure may be advised.

• Storage

  • Store in a cool, dry place, away from direct sunlight and moisture.
  • Keep out of reach of children.
  • Store at room temperature between 20° to 25°C.

OLVANCE H 40MG TABLET is a combination medication containing Olmesartan Medoxomil (an angiotensin II receptor blocker) and Hydrochlorothiazide (a thiazide diuretic). It is primarily used to treat high blood pressure (hypertension) in adults.

Here are some frequently asked questions about OLVANCE H 40MG TABLET:

What is OLVANCE H 40MG TABLET used for?

OLVANCE H 40MG TABLET is prescribed to treat high blood pressure (hypertension). Lowering blood pressure helps reduce the risk of serious cardiovascular events such as strokes and heart attacks. It is often used when blood pressure is not adequately controlled with Olmesartan alone.

How does OLVANCE H 40MG TABLET work?

This medication combines two active ingredients with different mechanisms of action to effectively lower blood pressure.

• Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB). It works by blocking the action of angiotensin II, a natural substance in the body that causes blood vessels to tighten and narrow. By blocking this action, Olmesartan relaxes the blood vessels, allowing blood to flow more easily and thus lowering blood pressure.
• Hydrochlorothiazide is a thiazide diuretic, also known as a "water pill." It helps the body get rid of excess fluid and salt by increasing the production of urine by the kidneys. This reduces the volume of blood that needs to be pumped, further contributing to lower blood pressure.

What is the usual dosage for OLVANCE H 40MG TABLET?

The recommended starting dose for OLVANCE H 40MG TABLET, especially for patients whose blood pressure is not adequately controlled with Olmesartan monotherapy, is 40 mg Olmesartan and 12.5 mg Hydrochlorothiazide (40/12.5 mg) once daily. Doses can be adjusted by your doctor, with a maximum generally not exceeding 40 mg Olmesartan and 25 mg Hydrochlorothiazide (40/25 mg) once daily. The tablet should be swallowed whole with water, and can be taken with or without food.

What are the possible side effects of OLVANCE H 40MG TABLET?

Common side effects can include dizziness, nausea, headache, and upper respiratory tract infections. Other possible side effects include fatigue, diarrhea, loss of appetite, and rash. Serious side effects, though less common, can include severe chronic diarrhea with weight loss, kidney problems, electrolyte imbalances (such as low potassium or high potassium), and eye problems like acute myopia or angle-closure glaucoma. If you experience severe or persistent side effects, contact your doctor immediately.

Is OLVANCE H 40MG TABLET safe during pregnancy or breastfeeding?

No, OLVANCE H 40MG TABLET is not considered safe during pregnancy and is not recommended, especially during the second and third trimesters, as it can cause harm or death to the unborn baby. If you become pregnant while taking this medicine, stop immediately and contact your doctor. It is also not recommended during breastfeeding, as hydrochlorothiazide can pass into breast milk and potentially cause side effects in the nursing infant.

Can OLVANCE H 40MG TABLET be taken with other medications?

Taking OLVANCE H 40MG TABLET with certain medications can lead to interactions. It is important to inform your doctor about all medications, supplements, and herbal products you are taking.

• Avoid taking with aliskiren if you have diabetes, or if you have moderate to severe renal impairment.
• Caution is advised with other drugs that raise serum potassium levels, such as potassium-sparing diuretics or potassium supplements, due to the risk of hyperkalemia.
• NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) may reduce the blood-pressure-lowering effects and increase the risk of kidney problems.
• If you are taking cholestyramine or colestipol, take OLVANCE H at least 4 hours before or 4-6 hours after these medications.
• Lithium levels may increase, leading to toxicity.
• ACE inhibitors and other angiotensin receptor blockers (ARBs) should generally be avoided due to increased risks of hypotension, hyperkalemia, and kidney impairment.

What precautions should be taken while using OLVANCE H 40MG TABLET?

• Monitor blood pressure regularly to track the effectiveness of the medication.
• Fluid and Electrolyte Imbalance: Be aware of symptoms like dry mouth, increased thirst, muscle cramps, or weakness, as hydrochlorothiazide can affect electrolyte levels. Your doctor may perform regular blood tests to monitor these.
• Dehydration: Drink plenty of fluids, especially in hot weather or during exercise, to prevent dehydration, which can lead to low blood pressure.
• Sun Sensitivity: This medicine can make your skin more sensitive to sunlight. Use sunscreen and avoid sunlamps or tanning beds.
• Kidney or Liver Problems: Inform your doctor if you have kidney or liver disease, as dosage adjustments or closer monitoring may be required.
• Diabetes: Hydrochlorothiazide may affect blood sugar levels, and dosage adjustments of antidiabetic drugs may be needed.
• Dizziness: Dizziness or lightheadedness can occur, especially when starting the medication. Avoid driving or operating machinery until you know how the medication affects you.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should OLVANCE H 40MG TABLET be stored?

Store the medicine in its closed container at room temperature, away from heat, moisture, and direct light. Keep it out of the reach of children. Do not store it in a bathroom.