Afoglip Tab

AFOGLIP Tablet

AFOGLIP Tablet is a medication manufactured by Torrent Pharmaceuticals Ltd., primarily used in the management of Type 2 Diabetes Mellitus.

• Name: AFOGLIP Tablet (Common name: Teneligliptin tablet)

• Composition: The active ingredient is Teneligliptin, typically in a strength of 20 mg.

• Uses: AFOGLIP Tablet is prescribed as an adjunct to diet and exercise to control elevated blood sugar levels in adult patients with Type 2 Diabetes Mellitus. It works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which in turn increases the levels of incretin hormones. These hormones stimulate insulin secretion from the pancreas and reduce glucagon levels, thereby helping to lower blood glucose, especially post-meal. Consistent blood sugar control with AFOGLIP Tablet can help reduce the risk of long-term diabetes-related complications such as kidney damage, nerve problems, and eye damage.

• Dosage and Administration: AFOGLIP Tablet should be taken as advised by a physician. It is typically taken once daily, preferably after meals or with food. The tablet should be swallowed whole with a glass of water and not crushed or chewed. The doctor determines the correct dose and duration of therapy based on the patient's age, body weight, and disease condition.

• Side Effects:

  • Common: Hypoglycemia (low blood sugar), headache, dizziness, constipation, diarrhea, and fever.
  • Serious (Rare): Inflammation of the pancreas (pancreatitis) and heart failure have been reported with similar medications, and patients should be aware of persistent severe stomach pain.

• Precautions:

  • AFOGLIP Tablet is contraindicated in patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, or known allergy to teneligliptin.
  • Caution is advised in pregnant or breastfeeding women; consultation with a doctor is necessary.
  • Inform your doctor if you have liver or heart problems, hormonal issues, stomach problems (e.g., surgery in the gut), are malnourished, starved, or on an irregular diet.
  • Monitor for symptoms of hypoglycemia, especially when driving or operating machinery.
  • Alcohol consumption should be discussed with a doctor as it can affect blood sugar levels.
  • Drug Interactions: Inform your doctor about all medicines you are taking, including other antidiabetic medications (e.g., glimepiride, metformin, insulin), beta-blockers, salicylic acid, certain antidepressants, adrenaline, thyroid hormones, and medicines for irregular heartbeats, to avoid potential interactions.

• Storage: Store AFOGLIP Tablet below 30°C (or below 25°C) in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children.

AFOGLIP TAB is a medication primarily used for the management of Type 2 Diabetes Mellitus. It contains Teneligliptin as its active ingredient.

Here are some frequently asked questions about AFOGLIP TAB:

What is AFOGLIP TAB used for?

AFOGLIP TAB is used to treat Type 2 Diabetes Mellitus in adults. It is typically prescribed when diet and exercise alone, or other medications, are not sufficient to control blood sugar levels. It helps prevent serious complications of diabetes such as kidney damage, blindness, nerve problems, and heart disease.

How does AFOGLIP TAB work?

AFOGLIP TAB contains Teneligliptin, which belongs to a class of medicines called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the levels of natural hormones called incretins in the body. Incretins help stimulate the pancreas to release more insulin when blood sugar levels are high and also reduce the amount of glucose produced by the liver. This dual action helps to lower both fasting and post-meal blood sugar levels.

What is the usual dosage for AFOGLIP TAB?

The dosage of AFOGLIP TAB is determined by your doctor based on your condition and blood sugar levels. It is generally taken once daily, with or without food, and should be taken at the same time each day to maintain consistent levels in your body. It is crucial to follow your doctor's instructions and not to alter the dose or discontinue the medicine without consulting them.

What are the possible side effects of AFOGLIP TAB?

Common side effects include hypoglycemia (low blood sugar), headache, dizziness, constipation, diarrhea, and upper respiratory tract infections. More serious, though rare, side effects can include inflammation of the pancreas (pancreatitis) and heart failure. It is important to recognize the symptoms of hypoglycemia (e.g., lightheadedness, sweating, shakiness) and know how to manage them, often by consuming sugary foods. If side effects persist, worsen, or if you experience severe abdominal pain, contact your doctor immediately.

Is AFOGLIP TAB safe during pregnancy or breastfeeding?

AFOGLIP TAB may be unsafe to use during pregnancy, and limited information is available. Animal studies have shown harmful effects on developing babies. Therefore, it should be used in pregnant women only if prescribed by a physician after weighing the benefits and potential risks. Breastfeeding should generally be stopped during treatment with AFOGLIP TAB as it is probably unsafe. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can AFOGLIP TAB be taken with other medications?

AFOGLIP TAB can interact with other medications. Taking it with other antidiabetic medicines, especially insulin or sulfonylureas, can increase the risk of hypoglycemia (low blood sugar). Caution is also advised with certain antifungals (like ketoconazole), antibiotics (like rifampicin), beta-blockers, salicylates (like aspirin), medicines for psychiatric illness, steroids, adrenaline, and thyroid hormones, as they can interfere with its action or affect blood sugar levels. Always inform your doctor about all other medicines, supplements, or herbal products you are taking to avoid potential interactions.

What precautions should be taken while using AFOGLIP TAB?

AFOGLIP TAB is not suitable for patients with Type 1 diabetes mellitus or diabetic ketoacidosis. Inform your doctor if you have a history of kidney disease, heart disease, or pancreas problems, as caution may be needed or the medicine might be contraindicated in severe cases. Excessive alcohol consumption should be limited or avoided as it can increase the risk of low blood sugar. Due to the potential for hypoglycemia, exercise caution while driving or operating machinery. Regular monitoring of blood sugar levels is important to ensure the medicine is working effectively.

What happens if a dose of AFOGLIP TAB is missed?

If you miss a dose of AFOGLIP TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should AFOGLIP TAB be stored?

AFOGLIP TAB should be stored in a cool, dry place, ideally below 30°C, away from direct sunlight and moisture. Keep it out of the sight and reach of children. Ensure that the medicine is used before its expiry date.