Nezalast Nasal Spary

NEZALAST NASAL SPRAY

NEZALAST Nasal Spray, manufactured by Sun Pharmaceutical Industries Ltd., is a prescription medicine designed to alleviate symptoms associated with allergic rhinitis.

• Composition NEZALAST Nasal Spray contains a combination of two active ingredients:

  • Fluticasone Propionate (50 mcg)
  • Azelastine Hydrochloride (140 mcg or 0.10% W/V)

• Uses This nasal spray is primarily used for the treatment of:

  • Seasonal and perennial (year-round) allergic rhinitis.
  • Allergic symptoms such as sneezing, runny nose, nasal congestion (stuffy nose), and watery or itchy eyes. Fluticasone, a corticosteroid, works by reducing inflammation in the nasal passages, while Azelastine, an antihistamine, blocks histamine, a substance responsible for allergic reactions, thereby providing comprehensive relief from allergy symptoms.

• Dosage and Administration NEZALAST Nasal Spray is for intranasal use only.

  • Typical Guidance: It is generally recommended to spray twice daily into each nostril, or as directed by a healthcare professional.
  • Application: Before use, gently blow your nose and shake the bottle well. Insert the nozzle into one nostril while closing the other. Direct the spray towards the side of the nostril (away from the nasal septum) and spray while inhaling gently through the nose. Repeat the process for the other nostril. Avoid blowing your nose immediately after use.
  • Important: Do not use more often or for a longer duration than prescribed, as this may worsen symptoms. NEZALAST Nasal Spray is not recommended for children below 6 years of age, and some sources suggest not below 12 years.

• Side Effects Common side effects may include:

  • Headache
  • Taste changes (often a bitter taste)
  • Nosebleeds
  • Nasal discomfort, irritation, or dryness
  • Sore throat or cough
  • Nausea More serious, though less common, side effects can occur. Consult your doctor if you experience changes in vision, severe nosebleeds, or signs of infection.

• Precautions

  • Allergies: Do not use if you are allergic to fluticasone, azelastine, or any other components of the spray.
  • Immune System: NEZALAST may weaken the immune system, increasing the risk of infections. Inform your doctor if you have active infections (e.g., tuberculosis, herpes infection of the eyes), recent nasal surgery, injury, or ulcers in the nose.
  • Pregnancy & Breastfeeding: Consult your doctor before using if pregnant or breastfeeding. It is advised only if the potential benefits outweigh the risks.
  • Vision: Use with caution if you have glaucoma or cataracts, as corticosteroids may worsen these conditions.
  • Alcohol & Driving: Azelastine may cause drowsiness in some individuals, so exercise caution when driving or operating machinery until you know how the medicine affects you. Avoid alcohol consumption as it may increase certain side effects.
  • Drug Interactions: Inform your doctor about all current medications, especially potent CYP3A4 inhibitors (e.g., ritonavir, ketoconazole) and cimetidine, as they can increase the systemic levels and efficacy of the nasal spray components.
  • Underlying Conditions: Caution is advised for patients with liver or kidney problems.

• Storage Store NEZALAST Nasal Spray in a cool and dry place, away from direct sunlight. Maintain storage temperatures between 10ºC to 30ºC (or 15°C–30°C). Keep out of the sight and reach of children and pets. Do not use the medicine after its expiry date.

What is Nezalast Nasal Spray used for?

Nezalast Nasal Spray is a combination medicine primarily used to relieve symptoms associated with allergic rhinitis, such as sneezing, runny nose, stuffy nose, nasal congestion, and itchy or watery eyes.

How does Nezalast Nasal Spray work?

Nezalast Nasal Spray contains two active ingredients: Fluticasone Propionate and Azelastine. Fluticasone Propionate is a corticosteroid that works by reducing inflammation and irritation in the nasal passages. Azelastine is an antihistamine that blocks the action of histamine, a chemical responsible for causing allergic reactions like sneezing and runny nose. Together, they effectively relieve allergy symptoms and reduce nasal inflammation.

What is the usual dosage of Nezalast Nasal Spray?

The usual recommended dose is typically one spray in each nostril once or twice a day, or as directed by your doctor. The specific dosage and duration of treatment will be determined by your doctor based on your condition and response to treatment. It is important to blow your nose gently before use, shake the bottle, and direct the spray towards the sides of your nostril.

What are the possible side effects of Nezalast Nasal Spray?

Common side effects can include headache, nosebleeds, an unpleasant or bitter taste in the mouth, nasal discomfort or irritation, pharyngitis (sore throat), and cough. Most of these side effects are usually temporary and resolve over time. If any side effects persist or worsen, consult your doctor.

Is Nezalast Nasal Spray safe during pregnancy?

Nezalast Nasal Spray should be used during pregnancy only if clearly needed and after discussing the potential risks and benefits with your doctor. While some animal studies have shown harmful effects on a developing baby, limited human studies exist. It is generally advised to exercise caution.

Is Nezalast Nasal Spray safe during breastfeeding?

It is generally considered probably safe to use Nezalast Nasal Spray during breastfeeding if prescribed by your doctor. Limited human data suggests that the active ingredients are unlikely to pose a significant risk to the baby, as only a tiny amount is expected to pass into breast milk. However, some sources suggest that larger or more prolonged use of azelastine nasal spray might cause drowsiness in the infant or decrease milk supply, and the bitter taste of azelastine might lead to the baby rejecting breastfeeding. Always consult your healthcare provider to ensure safe use for both mother and infant.

Can Nezalast Nasal Spray be taken with other medications?

Nezalast Nasal Spray may interact with certain medications. It is important to inform your doctor about all current medications, including over-the-counter drugs, herbal supplements, and other nasal sprays. Specific interactions have been noted with medicines like glucocorticoids, ritonavir, cobicistat-containing products, certain anticonvulsants (e.g., gabapentin, pregabalin), and some antidepressants. Alcohol consumption should also be avoided as it may worsen some side effects.

What precautions should be taken when using Nezalast Nasal Spray?

Avoid using Nezalast Nasal Spray if you are allergic to any of its ingredients. Inform your doctor if you have any existing infections (such as tuberculosis, fungal, bacterial, or viral infections), liver or kidney problems, glaucoma, cataracts, or if you have recently had nasal surgery, injury, or ulcers inside the nose, as it may increase the risk of nosebleeds or ulceration. It is generally not recommended for children under 6 years of age. This medicine may cause drowsiness in some individuals, so caution is advised when driving or operating machinery until you know how it affects you.

What happens if a dose of Nezalast Nasal Spray is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should Nezalast Nasal Spray be stored?

Nezalast Nasal Spray should be stored at room temperature, typically between 15°C and 30°C (59°F and 86°F), in an upright position. Keep it away from heat, direct light, and moisture. Do not freeze the medicine. Ensure it is kept out of the reach of children and pets, and do not use it after the expiry date.