Tripinom 20 Mg Tablet (15 Tab)

TRIPINOM 20 MG TABLET, manufactured by Lupin Ltd., is a combination medication primarily used for the management of high blood pressure (hyhypertension). This medicine is prescribed when blood pressure is not adequately controlled by a single medication. By effectively lowering blood pressure, it helps to reduce the risk of serious cardiovascular events such as heart attack, stroke, and kidney complications.

Composition

TRIPINOM 20 MG TABLET contains a triple combination of active ingredients:

• Olmesartan Medoxomil (20 mg): An angiotensin II receptor blocker (ARB) that helps relax and widen blood vessels, promoting smoother blood flow.
• Amlodipine (5 mg): A calcium channel blocker that relaxes the heart muscles and blood vessels, making it easier for the heart to pump blood.
• Hydrochlorothiazide (12.5 mg): A diuretic (water pill) that increases the excretion of water and sodium from the body, thereby reducing fluid volume and lowering blood pressure.

Uses

TRIPINOM 20 MG TABLET is prescribed for:

• Treatment of high blood pressure (hypertension).
• Reducing the risk of future heart attacks, strokes, and kidney damage associated with uncontrolled hypertension.

Dosage and Administration

• Take TRIPINOM 20 MG TABLET exactly as directed by your doctor.
• It can be taken with or without food.
• Swallow the tablet whole with water; do not crush, chew, or break it.
• For consistent blood pressure control, it is advisable to take the medicine at the same time each day.
• Do not stop taking this medication abruptly without consulting your doctor, as it can lead to a rise in blood pressure and increased risk of heart attack and stroke.
• This medicine is not recommended for use in children below 18 years of age.

Side Effects

Common side effects may include:

• Headache, dizziness, and sleepiness
• Swelling in ankles or feet (peripheral edema)
• Nausea, upset stomach, diarrhea
• Cough and fatigue

Serious side effects are less common, but seek immediate medical attention if you experience:

• Symptomatic hypotension (low blood pressure)
• Irregular heartbeats
• Severe skin reactions
• Unexplained muscle pain, dark-colored urine, or weakness (which could indicate a skeletal muscle problem leading to kidney failure)

Precautions

• Allergies: Avoid if allergic to Amlodipine, Olmesartan, Hydrochlorothiazide, or any other components of the tablet.
• Pregnancy and Breastfeeding: Not recommended during pregnancy (Category D) as it may harm the unborn baby, especially after the first three months. It is also not recommended during breastfeeding.
• Medical Conditions: Use with caution if you have kidney or liver problems, diabetes, congestive heart failure, or conditions causing volume depletion (e.g., severe diarrhea or vomiting).
• Drug Interactions: Inform your doctor about all other medicines you are taking, as interactions can occur. Coadministration with Aliskiren is not recommended if you have diabetes or moderate to severe kidney impairment.
• Dietary: Avoid consuming grapefruit or its juice while on treatment. Limit potassium-rich foods and potassium supplements.
• Alcohol: Excessive alcohol consumption may increase the risk of side effects.
• Driving: May cause drowsiness or dizziness; exercise caution when driving or operating machinery.

Storage

• Store at room temperature (20-25°C).
• Keep away from direct sunlight, excessive heat, and moisture.
• Ensure the medicine is out of reach of children and pets.
• Check the expiration date before use.

What is TRIPINOM 20 MG TABLET used for?

TRIPINOM 20 MG TABLET is primarily used to treat hypertension, also known as high blood pressure. This medication is a combination of three active ingredients and is typically prescribed when a single medication is not sufficient to control blood pressure. By lowering high blood pressure, it helps reduce the risk of heart-related complications such as heart attack and stroke.

How does TRIPINOM 20 MG TABLET work?

TRIPINOM 20 MG TABLET contains Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide, each working in a different way to lower blood pressure. Olmesartan Medoxomil is an angiotensin receptor blocker (ARB) that relaxes and widens narrowed blood vessels. Amlodipine is a calcium channel blocker that reduces the heart's workload, making it more efficient at pumping blood. Hydrochlorothiazide is a diuretic (water pill) that helps remove excess fluid and electrolytes from the body, further contributing to lower blood pressure.

What is the usual dosage of TRIPINOM 20 MG TABLET?

TRIPINOM 20 MG TABLET contains Olmesartan Medoxomil (20mg), Amlodipine (5mg), and Hydrochlorothiazide (12.5mg). The specific dose will be determined by your doctor based on your health condition and how your body responds to the medication. It is important to take this medicine exactly as prescribed by your doctor, usually once a day, with or without food.

What are the possible side effects of TRIPINOM 20 MG TABLET?

Common side effects can include headache, dizziness, nausea, stomach pain, diarrhea, constipation, fatigue, weakness, sleepiness, and swelling in the ankles or feet. You might also experience increased urination due to the diuretic component. Less common but serious side effects can include symptoms of liver problems, severe muscle pain, or allergic reactions. If any side effects persist or worsen, or if you experience serious symptoms, contact your doctor immediately.

Is TRIPINOM 20 MG TABLET safe during pregnancy or breastfeeding?

No, TRIPINOM 20 MG TABLET is not recommended for use during pregnancy as it may cause harm to the unborn baby. It is categorized as a Category D pregnancy drug. Similarly, it is not recommended during breastfeeding because components of the medication can pass into breast milk and potentially harm the baby. Your doctor may suggest an alternative treatment if you are pregnant or breastfeeding.

Can TRIPINOM 20 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications, vitamins, and herbal supplements you are taking to avoid potential drug interactions. For instance, combining TRIPINOM 20 MG TABLET with other blood pressure-lowering medications like aliskiren is generally not recommended, especially for diabetic patients. Your doctor will assess your current medications to ensure safe use.

What precautions should be taken while taking TRIPINOM 20 MG TABLET?

Before taking this medication, inform your doctor if you have any liver or kidney problems, diabetes, or a history of severe dehydration. Avoid consuming grapefruit or grapefruit juice as it may severely decrease your blood pressure. Excessive alcohol consumption is also unsafe as it may worsen side effects like dizziness and drowsiness. You should monitor your blood pressure, kidney function, electrolyte levels, and blood sugar regularly as advised by your doctor. If you experience dizziness or drowsiness, avoid driving or operating machinery.

What happens if a dose of TRIPINOM 20 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

How should TRIPINOM 20 MG TABLET be stored?

TRIPINOM 20 MG TABLET should be stored at room temperature, typically between 20°C to 25°C (68°F to 77°F). Keep the medicine in a closed container, away from heat, moisture, and direct light. Ensure it is kept out of the reach of children. Do not use outdated medicine.