Rozucor F 20 Mg Tablet (10 Tab)

ROZUCOR F 20 MG TABLET is a medication manufactured by Torrent Pharmaceuticals Ltd., primarily used to manage high cholesterol and triglyceride levels.

Name

• Common Name: Rozucor F 20 Tablet
• Brand Name: ROZUCOR F

Composition

Each tablet contains a combination of two active ingredients:

• Fenofibrate: 160 mg
• Rosuvastatin: 20 mg

Uses

ROZUCOR F 20 MG TABLET is prescribed for the following medical conditions:

• Lowering high levels of total cholesterol, "bad" cholesterol (LDL), and triglycerides in the blood (hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, mixed dyslipidemia).
• Boosting "good" high-density lipoprotein (HDL) cholesterol levels.
• Reducing the risk of heart disease, including heart attacks and strokes, especially in individuals with existing heart disease or multiple risk factors.

Dosage and Administration

• The typical dosage is one tablet once daily, as advised by your doctor.
• It can be taken with or without food, but it is recommended to take it at the same time each day to help remember the dose.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• The doctor will prescribe the right dose and duration based on lipid levels and patient response.

Side Effects

Common Side Effects:

• Headache
• Muscle pain, weakness, or tenderness
• Nausea, stomach pain/abdominal pain, constipation, flatulence/excessive gas
• Joint pain
• Abnormal liver function tests
• Elevated creatine kinase
• Increased blood sugar levels

Serious Side Effects (consult your doctor immediately if experienced):

• Myopathy and rhabdomyolysis (severe muscle breakdown, especially if accompanied by fever, weakness, or reddish-brown urine)
• Liver damage (symptoms like fever, rash, loss of appetite, nausea, vomiting, fatigue, dark urine, yellow skin or eyes)
• Severe allergic skin reactions (skin rash, itching, redness with blisters or peeling, swelling of face/tongue/throat, breathing difficulties)
• Severe stomach pain due to inflammation of the pancreas (pancreatitis)

Precautions

• Contraindications: Not recommended for use in patients with severe liver disease, active liver disease, severe kidney impairment, gallbladder disease, or those allergic to its ingredients.
• Pregnancy and Breastfeeding: Highly unsafe and not recommended during pregnancy or breastfeeding. Women of childbearing potential should use suitable contraceptive methods.
• Alcohol Consumption: Limit or avoid alcohol as it may increase the risk of liver problems.
• Medical Conditions: Use with caution in patients with pre-existing kidney disease, liver disease, muscle disorders, diabetes, or thyroid problems.
• Drug Interactions: Inform your doctor about all other medications, including blood thinners (e.g., warfarin), ciclosporin, other lipid-lowering medicines (e.g., gemfibrozil), bile acid sequestrants, and oestrogen-containing oral contraceptives, as interactions may occur.
• Monitoring: Regular monitoring of liver function, kidney function, blood sugar levels, muscle functions, and blood cholesterol levels is advised.

Storage

• Store at room temperature, ideally below 25°C or 30°C.
• Keep the product in a tightly sealed container to protect it from light and moisture.
• Always ensure the medicine is stored out of reach of children and pets.

Here are frequently asked questions about ROZUCOR F 20 MG TABLET:

What is ROZUCOR F 20 MG TABLET used for?

ROZUCOR F 20 MG TABLET is a combination medicine primarily used to lower high levels of cholesterol and triglycerides in the blood. It is prescribed when lifestyle changes like diet and exercise alone have not been sufficient. By reducing "bad" cholesterol (LDL) and triglycerides and increasing "good" cholesterol (HDL), it helps to reduce the risk of heart diseases, heart attacks, and strokes.

How does ROZUCOR F 20 MG TABLET work?

This medicine contains two active ingredients: Rosuvastatin (20 mg) and Fenofibrate (160 mg). Rosuvastatin is a statin that works by blocking an enzyme in the liver called HMG-CoA reductase, which is essential for cholesterol production, thereby reducing "bad" cholesterol. Fenofibrate works by activating a receptor (PPARα) that helps increase the breakdown of fatty substances and reduce triglyceride levels in the blood. Both components contribute to increasing "good" cholesterol (HDL).

What is the usual dosage for ROZUCOR F 20 MG TABLET?

Typically, ROZUCOR F 20 MG TABLET is taken once daily. It can be taken with or without food, but it is advisable to take it at the same time each day to maintain consistent levels in your body and help with remembering. Your doctor will determine the appropriate dosage and duration based on your lipid levels and response to the medicine.

What are the possible side effects of ROZUCOR F 20 MG TABLET?

Common side effects may include headache, muscle pain, joint pain, constipation, nausea, stomach pain, diarrhea, dizziness, fatigue, and abnormal liver function tests. More serious, though rare, side effects can include liver damage, and muscle disorders like myopathy or rhabdomyolysis, which may manifest as severe muscle pain or weakness, sometimes with fever or dark urine. Increased blood sugar levels can also occur.

Is ROZUCOR F 20 MG TABLET safe during pregnancy or breastfeeding?

No, ROZUCOR F 20 MG TABLET is considered highly unsafe and contraindicated during pregnancy, as studies have shown significant harmful effects to the developing baby. Women of childbearing potential should use effective contraception. It is also generally not recommended during breastfeeding, as components of the medicine may pass into breast milk and potentially harm the infant.

Can ROZUCOR F 20 MG TABLET be taken with other medications?

ROZUCOR F 20 MG TABLET can interact with several other medicines. It may increase the risk of bleeding when taken with blood thinners like warfarin. Concomitant use with immunosuppressants (e.g., ciclosporin) may lead to kidney damage. There is an increased risk of muscle disorders if taken with certain other cholesterol-lowering medicines (e.g., gemfibrozil, other statins) or certain antibiotics (e.g., fusidic acid). Antacids can decrease the concentration of rosuvastatin in the blood, and antiviral medicines like ritonavir may delay rosuvastatin elimination. Always inform your doctor about all medications you are taking.

What precautions should be taken while taking ROZUCOR F 20 MG TABLET?

Precautions include using it with caution if you have kidney or liver disease (it is not recommended for severe cases, and liver function should be monitored). You should also inform your doctor if you experience unexplained muscle pain or weakness, have a history of muscle disorders, or have diabetes, as the medicine may increase blood sugar levels. Alcohol consumption is generally unsafe and should be limited or avoided due to increased risk of liver issues. It's also not recommended if you have gallbladder disease. This medicine should always be used in conjunction with a healthy diet and regular exercise, and you should not stop taking it without consulting your doctor.

What happens if a dose of ROZUCOR F 20 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should ROZUCOR F 20 MG TABLET be stored?

ROZUCOR F 20 MG TABLET should be stored at room temperature, ideally below 30°C (or 25°C), in a tightly sealed container. Keep it protected from light and moisture, and always ensure it is kept out of the reach of children.