Gluvilda D 5 Mg Tablet (10 Tab)

GLUVILDA D 5 MG Tablet

GLUVILDA D 5 MG Tablet is a combination medication prescribed for the management of Type 2 Diabetes Mellitus in adults. It is manufactured by Alkem Laboratories Ltd..

• Name:
  • Brand Name: GLUVILDA D 5 MG Tablet, GLUVILDA D 5 Tablet SR
• Composition:
  • GLUVILDA D 5 MG Tablet contains two active ingredients: Dapagliflozin (5 mg) and Vildagliptin (100 mg).
  • Dapagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitor, which works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine and thus lowering blood sugar levels.
  • Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the body's natural hormones (incretins) involved in blood sugar control by increasing insulin release after meals and decreasing sugar production by the liver.
• Uses:
  • This medicine is used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus, particularly when blood sugar is not adequately controlled by metformin monotherapy or other medicines, along with a healthy diet and regular exercise.
  • It helps improve glycemic control, enhances glucose-dependent insulin secretion, reduces inappropriate glucagon secretion, and increases urinary glucose excretion.
  • GLUVILDA D 5 MG Tablet can also help reduce the risk of cardiovascular events and worsening kidney disease in individuals with Type 2 Diabetes Mellitus who also have cardiovascular disease.
• Dosage and Administration:
  • GLUVILDA D 5 MG Tablet should be taken exactly as prescribed by your doctor.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • It can be taken with or without food, preferably at the same time each day to maintain consistent blood sugar levels.
  • Do not stop taking the medication without consulting your doctor, as this could lead to increased blood sugar levels and serious complications.
• Side Effects:
  • Common Side Effects: Hypoglycemia (low blood sugar, especially when taken with other diabetes medications), urinary tract infections (UTIs), genital infections (vaginal yeast infections, balanitis), headaches, dizziness, tremors, nausea, frequent urination, back pain, rash, fatigue, and joint pain (arthralgia).
  • Serious Side Effects (Contact your doctor immediately): Angioedema (swelling of face, throat, or tongue, trouble swallowing and breathing), liver inflammation (yellowing of skin and eyes, nausea, loss of appetite, dark-colored urine), and inflammation of the pancreas (severe stomach pain radiating to the back, nausea, vomiting).
• Precautions:
  • Inform your doctor if you have kidney or liver issues, urinary tract infections, or if you are taking diuretics (water pills).
  • Pregnant or breastfeeding women should consult their doctor before use.
  • Avoid excessive alcohol consumption as it may increase the risk of side effects like hypoglycemia.
  • Monitor your blood sugar levels regularly while on this treatment.
  • It is not recommended for use in children.
  • Caution is advised if you have a history of pancreatitis.
• Storage:
  • Store in a cool and dry place away from sunlight.
  • Keep out of the sight and reach of children.
  • Generally, it should be stored at room temperature, protected from moisture and heat (below 30°C).

GLUVILDA D 5 MG TABLET (10 TAB) by ALKEM LABORATORIES LTD. is a combination medication containing Dapagliflozin (5 mg) and Vildagliptin (100 mg). It is primarily used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus.

What is GLUVILDA D 5 MG TABLET used for?

GLUVILDA D 5 MG TABLET is used to treat Type 2 Diabetes Mellitus in adults. It helps control high blood glucose levels, particularly when metformin monotherapy is not sufficient. This medication, along with diet and exercise, helps improve blood sugar control and can reduce the risk of diabetes-related complications such as kidney damage, eye damage, nerve problems, and cardiovascular events.

How does GLUVILDA D 5 MG TABLET work?

GLUVILDA D 5 MG TABLET contains two active ingredients: Dapagliflozin and Vildagliptin.

• Dapagliflozin is a sodium-glucose cotransporter-2 (SGLT2) inhibitor. It works by blocking the reabsorption of glucose in the kidneys, leading to increased excretion of excess glucose through urine, thereby lowering blood sugar levels.
• Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases the levels of certain natural substances (incretin hormones like GLP-1 and GIP) that help regulate blood sugar by enhancing insulin release after meals and decreasing the amount of sugar produced by the liver.

What is the usual dosage?

The dosage of GLUVILDA D 5 MG TABLET will be determined by your doctor, based on your health condition and how you respond to the medicine. It is usually taken as a whole tablet with a glass of water, with or without food, preferably at the same time each day to maintain consistent blood sugar levels. Do not crush, chew, or break the tablet.

What are the possible side effects?

Common side effects of GLUVILDA D 5 MG TABLET can include:

• Vomiting, nausea, abdominal pain
• Headache, dizziness, tremors
• Frequent urination (polyuria)
• Genital fungal infections (e.g., vaginal inflammation, balanitis) and urinary tract infections (UTIs)
• Fatigue, rash, back pain
• Hypoglycemia (low blood sugar), especially when taken with other antidiabetic medicines or alcohol, or if a meal is delayed/skipped.
• Changes in blood cholesterol or fat levels, increased red blood cells, decreased creatinine clearance.

If these side effects persist or worsen, you should consult your doctor. Serious side effects like angioedema (swelling of face, throat, or tongue), liver inflammation, or inflammation of the pancreas require immediate medical attention.

Is it safe during pregnancy or breastfeeding?

GLUVILDA D 5 MG TABLET is generally not recommended during pregnancy or breastfeeding. If you are pregnant, planning pregnancy, or breastfeeding, it is crucial to inform your doctor, who will assess the benefits and risks and may prescribe an alternative.

Can it be taken with other medications?

GLUVILDA D 5 MG TABLET can interact with certain medications. It is important to inform your doctor about all other medicines, including over-the-counter drugs, herbal supplements, and other antidiabetic medications you are taking, to avoid potential interactions.

• Insulin and insulin secretagogues (e.g., sulfonylureas like glimepiride or glipizide) when used with GLUVILDA D 5 MG TABLET, may increase the risk of low blood sugar (hypoglycemia).
• Diuretics (water pills) such as furosemide or hydrochlorothiazide, when taken with GLUVILDA D 5 MG TABLET, may increase the risk of dehydration and low blood pressure.
• ACE inhibitors may increase the risk of angioedema.
• Corticosteroids (e.g., prednisolone, hydrocortisone) and thyroid hormones (e.g., levothyroxine) can affect blood sugar levels and may require dose adjustments.
• Medicines used to manage fits (e.g., phenytoin, phenobarbital) may also interact.

What precautions should be taken?

• Inform your doctor if you have any pre-existing or history of liver or kidney disease, heart problems, or hypertension.
• Avoid drinking alcohol while on this medication, as it can increase the risk of hypoglycemia and lactic acidosis.
• Maintain good hygiene to help prevent genital fungal infections.
• Stay well-hydrated by drinking plenty of fluids to prevent dehydration.
• This medicine may cause dizziness, so drive or operate machinery only if you are alert.
• GLUVILDA D 5 MG TABLET is not recommended for children as its safety and effectiveness have not been established.

What happens if a dose is missed?

If you miss a dose of GLUVILDA D 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Never change your dosage without consulting your doctor.

How should it be stored?

GLUVILDA D 5 MG TABLET should be stored in a cool and dry place, away from sunlight, at room temperature (10ºC to 25ºC or below 30ºC). Keep it out of the sight and reach of children.