Resophyl 150mg Tab

RESOPHYL 150MG TABLET

RESOPHYL 150MG TABLET is an anti-helminthic medication manufactured by EMPIAI PHARMACEUTICALS LTD.

• Name:

  • Brand Name: RESOPHYL 150MG TABLET
  • Common Name: Diethylcarbamazine Tablet (150mg)

• Composition:

  • The active ingredient is Diethylcarbamazine (150mg). It belongs to a class of medicines called Anthelmintics.

• Uses: RESOPHYL 150MG TABLET is used to treat and prevent various parasitic worm infections. It is effective against both larval and adult forms of parasitic worms.

  • Filarial infections (Filariasis), including Bancroft's filariasis, which can cause swelling of limbs and genitals.
  • Tropical eosinophilia.
  • Toxocariasis.
  • Loiasis (eye worm infections).
  • River blindness (Onchocerciasis).

• Dosage and Administration:

  • RESOPHYL 150MG TABLET should be taken in the dose and duration advised by your doctor.
  • It should be taken with food, preferably at a fixed time, to avoid stomach discomfort.
  • Swallow the tablet whole with water; do not crush, chew, or break it.
  • It is crucial to complete the full course of treatment even if symptoms improve, to ensure all parasites are killed and to prevent resistance or recurrence.
  • Do not take a double dose to make up for a missed dose; simply take the next scheduled dose.
  • For Filariasis, a typical dosage suggested is 2 mg/kg body weight, three times daily for 3 to 4 weeks, with treatment potentially repeated after 6 months. Initial doses may start lower (e.g., 1 mg/kg on the first day) and increase gradually.
  • Dosage for children should be determined by a doctor based on age, body weight, and disease condition.

• Side Effects: Common side effects may include:

  • Headache
  • Dizziness
  • Nausea and vomiting
  • Lassitude (lack of energy)
  • Abnormal liver function tests
  • Fever
  • Vertigo
  • Hair loss
  • Skin rash
  • Joint pain
  • Drowsiness If side effects persist or worsen, consult your doctor.

• Precautions:

  • Allergy: Avoid if allergic to diethylcarbamazine or any other ingredients.
  • Pregnancy: Generally not recommended during pregnancy. Use birth control measures while taking this medicine.
  • Breastfeeding: Generally not recommended for breastfeeding women as it is unknown if it passes into breast milk.
  • Kidney Disease: Not recommended for use in patients with kidney disease or impaired renal function.
  • Liver Disease: Use with caution in patients with liver diseases; limited information is available. Regular liver function tests may be monitored.
  • Seizures: Use with caution in patients with a history of seizures or convulsions.
  • Heart Disease: Not recommended for use in patients with heart disease.
  • Asthma: Patients with asthma should inform their doctor.
  • Driving/Operating Machinery: May cause drowsiness, dizziness, or affect vision. Avoid driving or operating machinery if affected.
  • Alcohol: Caution is advised as it may cause excessive drowsiness with alcohol. Alcohol can also affect liver functioning, which is relevant as the medicine is broken down in the liver.
  • Drug Interactions: May interact with blood pressure medicines (e.g., Bisoprolol, Acetabulol) causing a decrease in heart rate, and can decrease the effect of Amitriptyline.
  • Monitoring: Blood counts and liver function tests may be monitored throughout treatment.

• Storage:

  • Store RESOPHYL 150MG TABLET below 30°C.
  • Keep it in a closed, airtight container, protected from moisture, sunlight, and heat.
  • Keep out of sight and reach of children and pets.
  • Dispose of any unused medicine properly.

Frequently Asked Questions about RESOPHYL 150MG TABLET

What is RESOPHYL 150MG TABLET used for?

RESOPHYL 150MG TABLET, which contains Diethylcarbamazine, is an anthelmintic medicine primarily used to treat various parasitic worm infections. These include filarial infections (such as elephantiasis, loiasis, and lymphatic filariasis), tropical eosinophilia, toxocariasis, and river blindness (onchocerciasis). It targets and eliminates the worms responsible for these conditions.

How does RESOPHYL 150MG TABLET work?

RESOPHYL 150MG TABLET works by interfering with various processes essential for the survival of parasitic worms. Its active ingredient, Diethylcarbamazine, is effective against both the larval and adult forms of these worms. It sensitizes microfilariae to phagocytosis, allowing the body's immune cells (leukocytes) to target and destroy the parasites, thereby eliminating the infection.

What is the usual dosage for RESOPHYL 150MG TABLET?

The dosage of RESOPHYL 150MG TABLET depends on the specific condition, the patient's age, body weight, and medical status, and should always be advised by a physician. For filariasis, a common regimen involves taking 2 mg/kg body weight three times a day for 3 to 4 weeks, starting with 1 mg/kg on the first day. It should be taken with food. It is crucial to follow the prescribed dose and duration as directed by your doctor.

What are the possible side effects of RESOPHYL 150MG TABLET?

Common side effects include nausea, vomiting, headache, dizziness, abdominal pain, fever, and general weakness or lassitude (lack of energy). Other reported side effects may include unusual tiredness, hair loss, vertigo, skin rash, and abnormal liver function tests. If any side effects persist or worsen, it is important to consult your doctor.

Is RESOPHYL 150MG TABLET safe during pregnancy or breastfeeding?

RESOPHYL 150MG TABLET is generally not recommended for use in pregnant women as it can be harmful to an unborn baby. It should only be taken during pregnancy if specifically advised by a doctor due to potential severe side effects. Women of childbearing potential should use birth control measures while taking this medication.

For breastfeeding women, RESOPHYL 150MG TABLET is generally not recommended as it is not known whether it passes into breast milk, and it is considered probably unsafe. Consult your doctor before using this medicine while breastfeeding.

Can RESOPHYL 150MG TABLET be taken with other medications?

RESOPHYL 150MG TABLET may interact with certain other medications. For instance, it can cause a decrease in heart rate when taken with blood pressure medicines like Bisoprolol. It may also interact with certain psychiatric medications like Amitriptyline, potentially decreasing their effect. Severe interactions have been reported with Chloroquine, Quinine, and Mefloquine. It is important to inform your doctor about all other medicines, vitamin supplements, or herbal products you are taking to avoid potential drug interactions.

What precautions should be taken while using RESOPHYL 150MG TABLET?

It is important to take RESOPHYL 150MG TABLET with food to help avoid stomach discomfort. You should complete the full course of treatment as prescribed, even if you start feeling better, to ensure all parasites are killed and to prevent recurrence or resistance. This medicine may cause drowsiness or dizziness, so avoid driving or operating heavy machinery if you experience these effects. Caution is advised for patients with kidney disease, liver disease, seizures, or heart conditions. Your doctor may monitor blood counts and liver function tests throughout your treatment. Avoid alcohol consumption as it can affect liver function.

What happens if a dose of RESOPHYL 150MG TABLET is missed?

If you miss a dose of RESOPHYL 150MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the chances of side effects.

How should RESOPHYL 150MG TABLET be stored?

RESOPHYL 150MG TABLET should be stored in its original container, tightly closed, and kept below 30°C. Store it in a clean, dry place, protected from moisture, direct sunlight, and heat. Always keep this medicine out of the sight and reach of children and pets.