Mupinase Cream

Mupinase Cream is a topical antibiotic manufactured by Cipla Ltd. (Cresta Division), primarily used to treat various bacterial skin infections.

Name

• Common Name: Mupinase Cream
• Brand Name: MUPINASE CREAM by CIPLA-CRESTA DIV

Composition

• Active Ingredients: Mupirocin 2% w/w Mupirocin works by inhibiting bacterial protein synthesis, specifically by binding to isoleucyl-tRNA synthetase, which is essential for bacterial growth and survival. This action kills the bacteria or prevents their growth.

Uses

Mupinase Cream is prescribed for bacterial skin infections.

• Impetigo: A highly contagious skin infection characterized by red sores.
• Folliculitis: Inflammation of hair follicles.
• Furunculosis: Commonly known as boils.
• Infected Eczema: To manage secondarily infected skin disorders.
• Minor Skin Injuries: Used to treat and prevent infections in small cuts, wounds, abrasions, and minor burns. It is not effective against fungal or viral infections and should not be applied to burnt skin or open-cut wounds.

Dosage and Administration

Mupinase Cream is for external use only.

• Application: Clean and dry the affected area before application. Apply a small amount of the cream to the affected skin.
• Frequency: Typically applied 2-3 times daily, or as directed by a doctor.
• Duration: Use for the duration advised by your doctor, usually up to 10 days. Do not use for more than 10 days.
• Covering: The treated area can be covered with a dressing if needed.
• Hands: Wash hands before and after applying the cream, unless the hands are the area being treated.

Side Effects

Common side effects are usually temporary and include:

• Burning sensation
• Itching
• Rash
• Stinging sensation
• Pain Severe allergic reactions such as a raised and itchy rash, swelling, shortness of breath, or wheezing are rare but require immediate medical attention.

Precautions

• External Use Only: Avoid contact with eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with water.
• Allergies: Inform your doctor if you have a history of allergy to mupirocin or any other medicine.
• Damaged Skin: Avoid using on large areas of broken, damaged, or open skin.
• Pregnancy and Breastfeeding: Generally considered safe if prescribed, but consult your doctor before use. Avoid applying to the breast area if breastfeeding.
• Children: Use with caution in children less than 2 months of age.
• Prolonged Use: Do not use for longer than prescribed, as it may lead to the overgrowth of fungi or antibiotic resistance.
• No Improvement: If the skin condition does not improve within 3-5 days, consult your doctor.

Storage

• Store below 25°C or at room temperature in a cool, dry place, away from direct sunlight and out of reach of children.

Mupinase Cream, manufactured by Cipla-Cresta Div, is a topical antibiotic medication containing Mupirocin. It is primarily used to treat various bacterial skin infections.

What is Mupinase Cream used for?

Mupinase Cream is prescribed to treat bacterial skin infections such as impetigo (a highly contagious skin infection), folliculitis (inflammation of hair follicles), furunculosis (boils), and other infected skin disorders like eczema. It can also be used for infections in small cuts, lacerations, wounds, or scraped skin. It is important to note that Mupinase Cream is not effective against fungal or viral infections.

How does Mupinase Cream work?

Mupinase Cream contains Mupirocin, which is an antibiotic. It works by stopping the growth and spread of infection-causing bacteria. Specifically, Mupirocin inhibits the production of essential proteins that bacteria need to survive and multiply, ultimately killing them.

What is the usual dosage and how should it be applied?

Mupinase Cream is for external use only. It should be applied to the affected skin area as directed by your doctor, typically a thin layer applied three times a day. Before application, clean and dry the affected area. Wash your hands before and after applying the cream, unless your hands are the area being treated. Do not use the cream for more than 10 days unless advised by a doctor.

What are the possible side effects of Mupinase Cream?

Common side effects at the application site may include a minor burning sensation, itching, redness, irritation, stinging, pain, or rash. These reactions are usually temporary. Rarely, severe allergic reactions such as extensive rashes, swelling, or difficulty breathing can occur. If these symptoms persist or worsen, or if you experience severe abdominal cramps and diarrhea, stop using the cream and consult your doctor immediately.

Is Mupinase Cream safe during pregnancy or breastfeeding?

Pregnancy: It is generally considered safe to use Mupinase Cream during pregnancy, with animal studies showing low or no adverse effects. However, limited human data is available, so it is advisable to consult your doctor before use. Avoid applying it to large skin areas for prolonged durations. Breastfeeding: Use Mupinase Cream with caution during breastfeeding and consult your doctor. Limited safety data is available. If the cream is applied to a cracked nipple or breast area, wash the area thoroughly before feeding the baby to prevent accidental ingestion.

Can Mupinase Cream be taken with other medications?

Since Mupinase Cream is applied topically to the skin, it is less likely to interact with medicines taken orally. However, it may interact with other topically applied medicines. Always inform your doctor about all other medications, including prescription, non-prescription, herbal products, or supplements you are using.

What precautions should be taken while using Mupinase Cream?

Avoid contact of Mupinase Cream with your eyes, nose, or mouth. If accidental contact occurs, rinse the affected area thoroughly with water. Do not apply the cream on open wounds, broken, or severely damaged skin without specific medical advice. It is not recommended for children below 2 months of age. Discontinue use and consult your doctor if irritation, severe itching, or a rash develops, or if your condition does not improve within 3 to 5 days. Prolonged use may lead to the overgrowth of fungi.

What happens if a dose is missed?

If you miss an application of Mupinase Cream, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double amount to make up for a missed dose.

How should Mupinase Cream be stored?

Store Mupinase Cream at room temperature in a cool and dry place, typically below 25°C or 30°C. Protect it from direct sunlight, heat, and moisture, and do not freeze it. Always keep it out of the reach of children and pets.