Olkem-40 H Tablet

OLKEM-40 H TABLET

OLKEM-40 H TABLET is a combination medication manufactured by Alkem Laboratories Ltd., primarily used for the management of high blood pressure (hypertension).

• Composition

  • Each tablet contains Olmesartan Medoxomil 40mg and Hydrochlorothiazide 12.5mg.
  • Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that works by relaxing and widening blood vessels.
  • Hydrochlorothiazide is a diuretic ("water pill") that removes excess water, fluid, and certain electrolytes from the body by increasing urine production.

• Uses

  • Treatment of high blood pressure (hypertension).
  • Helps reduce fluid retention.
  • Lowers the risk of heart attacks, strokes, and kidney problems associated with uncontrolled high blood pressure.

• Dosage and Administration

  • Typically taken once daily, with or without food.
  • Swallow the tablet whole with water; do not crush, break, or chew.
  • It is advisable to avoid taking this medicine within four hours of going to bed due to its diuretic effect.
  • Follow the doctor's prescribed dosage and timing.

• Side Effects

  • Common: Nausea, upset stomach, dehydration, headache, diarrhea, electrolyte imbalance, dizziness, decreased blood pressure, weakness, tiredness, edema (swelling), upper respiratory tract infection, increased uric acid levels, increased triglyceride levels, back pain, joint pain, skeletal pain.
  • Serious: Severe allergic reactions (skin rash, itching, swelling of face/mouth/throat), severe persistent diarrhea with substantial weight loss, painful eyes or decreased vision, signs of electrolyte depletion (e.g., extreme thirst, dry mouth, muscle pain, rapid heart rate), high potassium levels (hyperkalemia), and significant drops in blood pressure (hypotension).

• Precautions

  • Avoid use during the second and third trimesters of pregnancy as it can harm the fetus.
  • Consult a doctor if breastfeeding, as the medicine may pass into breast milk.
  • Use with caution in patients with liver disease, kidney disease, or diabetes, as dosage adjustments or close monitoring may be required.
  • It may cause dizziness or drowsiness, so exercise caution when driving or operating machinery.
  • Avoid consuming alcohol, as it may increase drowsiness and reduce effectiveness.
  • Do not stop taking the medicine abruptly without consulting your doctor, as this may lead to an increase in blood pressure.
  • Inform your doctor about all other medications you are taking, especially other blood pressure medications, potassium supplements, NSAIDs, or antidiabetic agents, to prevent potential interactions.

• Storage

  • Store in a cool and dry place away from sunlight.
  • Keep out of sight and reach of children.
  • Store at room temperature between 10ºC to 25ºC or below 30ºC, protected from moisture and light.

OLKEM-40 H Tablet is a medication used to manage high blood pressure (hypertension). It combines two active ingredients, Olmesartan medoxomil and Hydrochlorothiazide, to effectively lower blood pressure and reduce the risk of associated heart-related complications like heart attacks, strokes, and kidney issues.

Here are some frequently asked questions about OLKEM-40 H Tablet:

What is OLKEM-40 H Tablet used for?

OLKEM-40 H Tablet is primarily used to treat hypertension (high blood pressure) in adults. It can also be used in combination with other antihypertensive agents for patients who require multiple medications to reach their blood pressure goals.

How does OLKEM-40 H Tablet work?

This medicine contains two active components: Olmesartan medoxomil and Hydrochlorothiazide. Olmesartan medoxomil is an angiotensin II receptor blocker (ARB) that works by blocking a substance in the body that causes blood vessels to tighten. This leads to the relaxation and widening of blood vessels, improving blood flow and lowering blood pressure. Hydrochlorothiazide is a diuretic (water pill) that helps the body get rid of excess water and salt through increased urine production, which also contributes to lowering blood pressure.

What is the usual dosage for OLKEM-40 H Tablet?

The daily dose of OLKEM-40 H Tablet should be taken as prescribed by your doctor. It is typically taken orally once a day, with or without food. You should swallow the tablet whole with water and avoid crushing or chewing it. It is important to take the medicine at the same time each day to maintain consistent blood levels.

What are the possible side effects of OLKEM-40 H Tablet?

Common side effects may include dizziness, headache, nausea, hyperuricemia (high levels of uric acid in the blood), hyperkalemia (high potassium levels), vertigo, rash, diarrhea, loss of appetite, weakness, tiredness, and swelling (edema). More serious but less common side effects can include severe allergic reactions, significant dehydration, or worsening kidney function. If you experience persistent or severe side effects, consult your doctor.

Is OLKEM-40 H Tablet safe during pregnancy or breastfeeding?

OLKEM-40 H Tablet is generally not recommended during pregnancy, especially during the second and third trimesters, as it can be harmful to the fetus. If you are breastfeeding, it's best to consult your doctor before taking this medicine, as limited information is available about its effect on breastmilk and the baby. Your doctor may advise you to stop breastfeeding or consider an alternative medication.

Can OLKEM-40 H Tablet be taken with other medications?

OLKEM-40 H Tablet can interact with several medications. It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking. Interactions can occur with potassium-enhancing medicines, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), antidiabetic medicines, lithium, ACE-inhibitors, and other angiotensin II receptor blockers. These interactions can affect the medicine's effectiveness or increase the risk of side effects like elevated potassium levels or kidney impairment.

What precautions should be taken while using OLKEM-40 H Tablet?

Discuss any pre-existing conditions with your doctor, especially kidney disease, liver disease, diabetes, heart failure, or a history of skin cancer. Caution is advised when consuming alcohol, as it can further lower blood pressure and increase dizziness. Regular monitoring of blood pressure, kidney function, and electrolyte levels is important during treatment. Protect your skin from sun exposure or UV rays, as long-term use may increase the risk of certain skin and lip cancers.

What happens if a dose of OLKEM-40 H Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, skip the missed one and continue with your regular dosage schedule. Do not double the dose to make up for a missed one without consulting your doctor.

How should OLKEM-40 H Tablet be stored?

OLKEM-40 H Tablet should be stored in a cool and dry place, below 30°C, away from direct sunlight, moisture, and heat. Keep it out of the reach and sight of children and pets.