Atormac 5 Mg Tablet (10 Tab)

ATORMAC 5 MG TABLET (10 TAB) by MACLEODS PHARMACEUTICALS LTD.

Name

• Brand Name: ATORMAC 5 MG TABLET
• Common Name: Atorvastatin

Composition Each tablet contains Atorvastatin 5 mg as the active ingredient.

Uses ATORMAC 5 MG TABLET is primarily used to lower elevated levels of "bad" cholesterol (Low-Density Lipoprotein or LDL) and triglycerides in the blood when diet and lifestyle changes alone are insufficient. By reducing cholesterol accumulation on artery walls, it plays a significant role in preventing cardiovascular diseases such as heart attacks, strokes, and angina. It is also prescribed for conditions like hypercholesterolemia, mixed dyslipidemia, hypertriglyceridemia, and familial hypercholesterolemia.

Dosage and Administration The typical dosage for ATORMAC 5 MG TABLET is once daily, taken at a consistent time each day, with or without food. The tablet should be swallowed whole with water and should not be chewed, crushed, or broken. For adults, the initial dose is generally 5 to 10 mg once daily, which may be adjusted by a healthcare provider at 4-week intervals. For children aged 10-17 years, the recommended initial dose is 5 mg once daily, which can be increased to a maximum of 20 mg per day at intervals of at least 4 weeks.

Side Effects

• Common Side Effects: Indigestion, abdominal pain/discomfort, diarrhea, constipation, flatulence, joint pain, muscle pain (myalgia), nasopharyngitis, nausea, pain in extremities, urinary tract infection, abnormal liver function tests, headache, fatigue, and muscle weakness. These are usually mild and may subside as the body adjusts to the medication.
• Serious Side Effects (consult a doctor if experienced): Yellowing of the eyes or skin (jaundice), unusually dark urine, severe stomach pains, repeated or unexplained muscle pain, tenderness or weakness (which could indicate rhabdomyolysis, a severe muscle breakdown leading to kidney failure), allergic reactions, and increased blood sugar levels.

Precautions ATORMAC 5 MG TABLET is contraindicated in individuals with active or severe liver disease, during pregnancy, and while breastfeeding due to potential harm to the mother and unborn child. It should not be used by individuals with a known allergy to atorvastatin.

• Warnings: Patients with kidney disease, diabetes (blood sugar levels should be monitored regularly), thyroid problems (hypothyroidism), severe lung disease, or a history of muscle disorders should inform their doctor before starting this medication. Excessive alcohol consumption should be avoided as it increases the risk of liver problems. Grapefruit juice should also be avoided as it may elevate atorvastatin levels and increase the risk of side effects.
• Drug Interactions: Caution is advised when taking ATORMAC 5 MG TABLET with immunosuppressants (e.g., cyclosporine), certain antibiotics (e.g., fusidic acid, erythromycin), antifungals (e.g., ketoconazole), anti-HIV medications, anti-TB agents (e.g., rifampicin), and other lipid-lowering agents (e.g., gemfibrozil, niacin). Regular monitoring of cholesterol levels and liver function tests is essential throughout the treatment. This medication is generally not recommended for children under 10 years of age.

Storage Store ATORMAC 5 MG TABLET in a cool and dry place, protected from direct sunlight, heat, and moisture. Keep the medicine out of the sight and reach of children. The recommended storage temperature is below 30°C or between 10ºC to 25ºC.

Here are some frequently asked questions about ATORMAC 5 MG TABLET:

What is Atormac 5 mg Tablet used for?

Atormac 5 mg Tablet contains Atorvastatin and is primarily used to lower high levels of cholesterol and triglycerides (fats) in the blood. It helps reduce "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL). By doing so, it helps prevent serious heart problems such as heart attacks and strokes, especially in individuals with existing heart conditions or risk factors. It is used in conjunction with a healthy diet, exercise, and weight management.

How does Atormac 5 mg Tablet work?

Atormac 5 mg Tablet belongs to a class of medications called statins, specifically HMG-CoA reductase inhibitors. It works by blocking an enzyme in the liver (HMG-CoA reductase) that is essential for the production of cholesterol. This action slows down cholesterol production in the body, which helps to decrease the amount of cholesterol that can build up on artery walls, thus improving blood flow to vital organs like the heart and brain.

What is the usual dosage of Atormac 5 mg Tablet?

For adults, the usual initial dose of atorvastatin (the active ingredient in Atormac 5 mg Tablet) for conditions like mixed dyslipidemia and hypercholesterolemia is typically 5 to 10 mg once daily, which may be adjusted at 4-week intervals by a doctor. It can be taken with or without food, but it is recommended to take it at the same time each day for consistent effectiveness. For children aged 10-17 years with heterozygous familial hypercholesterolemia, an initial dose of 5 mg once daily is common. Always follow your doctor's prescribed dosage and duration.

What are the possible side effects of Atormac 5 mg Tablet?

Common side effects can include muscle pain, joint pain, headache, nausea, diarrhea, dyspepsia (indigestion), abdominal pain, constipation, flatulence, and nasopharyngitis (inflammation of the throat and nasal passages). More serious, though rare, side effects can include liver damage (symptoms like yellowing skin/eyes, dark urine, upper right belly pain), and severe muscle problems such as myopathy or rhabdomyolysis (muscle pain, tenderness, or weakness, especially with unusual tiredness or fever, and dark-colored urine). If you experience persistent or severe side effects, particularly unexplained muscle pain, weakness, or any signs of liver problems, consult your doctor immediately.

Is Atormac 5 mg Tablet safe during pregnancy or breastfeeding?

Atormac 5 mg Tablet (Atorvastatin) is generally not recommended and is contraindicated during pregnancy as it can harm the unborn baby. Women who are pregnant or planning a pregnancy should stop taking this medicine and inform their doctor immediately. It is also advised to use caution or avoid Atormac 5 mg Tablet during breastfeeding. While some evidence suggests very low amounts may pass into breast milk with minimal infant absorption, an alternative drug may be preferred, especially for newborns or premature infants. Consult your doctor or pharmacist to weigh the potential benefits against the risks.

Can Atormac 5 mg Tablet be taken with other medications?

Atormac 5 mg Tablet can interact with several other medications, which may increase the risk of side effects or reduce its effectiveness. Important interactions include:

• Certain antibiotics: Such as clarithromycin, erythromycin, and fusidic acid.
• Antifungals: Such as ketoconazole and itraconazole.
• HIV and Hepatitis C medicines: Specific protease inhibitors can interact.
• Blood thinners: Like warfarin, which may require increased monitoring.
• Immunosuppressants: Such as ciclosporin or tacrolimus, which can increase the risk of muscle damage.
• Other cholesterol-lowering drugs: Especially fibrates (e.g., gemfibrozil, fenofibrate) and niacin, which can increase the risk of muscle-related side effects.
• Birth control pills: Atorvastatin may increase the levels of hormones in birth control pills, increasing the risk of side effects.
• Colchicine: Used for gout.
• Certain blood pressure medications: Like amlodipine, diltiazem, verapamil, and amiodarone. Always inform your doctor or pharmacist about all prescription, over-the-counter medicines, herbal remedies (like St. John's wort), and supplements you are taking to prevent potential interactions.

What precautions should be taken while using Atormac 5 mg Tablet?

Several precautions should be taken:

• Liver Disease: Atormac is contraindicated in individuals with active liver disease or unexplained persistent elevated liver enzyme levels. Regular liver function monitoring is recommended.
• Kidney Problems: Individuals with kidney problems may have an increased risk of muscle breakdown and should be monitored closely.
• Diabetes: Atorvastatin may increase blood sugar levels, so diabetic patients should monitor their blood sugar carefully.
• Alcohol: Avoid consuming large amounts of alcohol as it can increase the risk of liver problems.
• Grapefruit Juice: Avoid drinking large amounts of grapefruit juice, as it can increase the concentration of atorvastatin in the blood, raising the risk of muscle problems.
• Muscle Problems: Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, especially if accompanied by fever or dark urine.
• Thyroid Disorders: Patients with hypothyroidism should use this medicine with caution.
• Age: Elderly patients may have an increased risk of muscle problems. Regular monitoring of cholesterol and liver enzyme levels is important during treatment.

What happens if a dose of Atormac 5 mg Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is more than 12 hours late or almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose or extra doses to make up for a missed one, as this may increase the risk of side effects.

How should Atormac 5 mg Tablet be stored?

Atormac 5 mg Tablet should be stored at room temperature, typically between 20°C and 25°C (68°F and 77°F). Keep it away from heat, direct light, and moisture or damp areas like bathrooms. Ensure it is stored out of the reach of children and pets. Do not keep outdated medicine or medicine that is no longer needed.