Pentanerv Nt 100 Mg Tablet (10 Tab)

PENTANERV NT 100 MG TABLET

Pentanerv NT 100 mg Tablet is a combination medication manufactured by Alkem Laboratories Ltd., primarily used for the management of neuropathic pain.

Composition

Pentanerv NT 100 mg Tablet contains two active ingredients:

• Gabapentin (100 mg)
• Nortriptyline (10 mg)

Uses

This medicine is prescribed for the treatment of long-lasting (chronic) neuropathic pain in adults, which originates from nerve damage or dysfunction. This includes pain caused by conditions such as:

• Diabetic neuropathy (nerve damage in people with diabetes)
• Postherpetic neuralgia (pain after shingles)
• Spinal cord injury It may also be used for restless leg syndrome, fibromyalgia, and as an adjunctive therapy for depression.

Dosage and Administration

Pentanerv NT 100 mg Tablet is taken orally, with or without food, preferably in the evening or at night. It is important to take it at a fixed time each day to maintain consistent medicine levels in the bloodstream. Do not chew, crush, or break the tablet. Do not stop taking this medicine abruptly, as it may lead to withdrawal symptoms; the dose should be gradually reduced under medical supervision.

Side Effects

Common side effects may include:

• Dizziness, drowsiness, fatigue, tiredness
• Dry mouth
• Constipation, difficulty in urination
• Weight gain
• Blurred vision
• Headache, nausea, vomiting
• Orthostatic hypotension (sudden drop in blood pressure upon standing), increased heart rate

Serious side effects, though less common, require immediate medical attention and include unusual changes in mood or behavior (e.g., suicidal thoughts), severe allergic reactions, signs of liver problems (jaundice), or severe muscle pain/weakness.

Precautions

• Allergies: Inform your doctor if you are allergic to any components of the tablet.
• Medical History: Inform your doctor if you have a history of heart problems, bipolar syndrome, or kidney or liver disease.
• Pregnancy & Breastfeeding: Consult your doctor before use if you are pregnant or breastfeeding.
• Alcohol & Driving: Avoid alcohol consumption as it can increase dizziness and drowsiness. Do not drive or operate machinery until you know how the medicine affects you.
• Drug Interactions: Antacids should be taken at least 2 hours before or after Pentanerv NT 100 mg Tablet.
• Pediatric Use: Not recommended for use in children and adolescents under 18 years of age.
• Elderly Use: Use with caution in elderly patients.

Storage

Store Pentanerv NT 100 mg Tablet in a cool, dry place, away from direct sunlight, and out of the reach of children. Typically, it should be stored below 30°C or between 10ºC to 25ºC.

PENTANERV NT 100 MG TABLET is a combination medication containing Gabapentin (100 mg) and Nortriptyline (10 mg), primarily used to manage neuropathic pain.

What is PENTANERV NT 100 MG TABLET used for?

PENTANERV NT 100 MG TABLET is used to treat neuropathic pain, which is nerve pain caused by damage or injury to the nerves. This can occur due to various conditions such as diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), spinal cord injury, HIV infection, cancer, or thyroid problems. It also helps in improving mood, sleep patterns, and reducing fatigue associated with persistent discomfort.

How does PENTANERV NT 100 MG TABLET work?

This medicine combines two active ingredients: Gabapentin and Nortriptyline. Gabapentin works by modulating calcium channel activity in nerve cells, thereby interfering with the transmission of pain signals. Nortriptyline, a tricyclic antidepressant, increases the levels of chemical messengers (serotonin and noradrenaline) in the brain, which helps to block pain signals. Together, they effectively reduce nerve-related pain.

What is the usual dosage for PENTANERV NT 100 MG TABLET?

The dosage of PENTANERV NT 100 MG TABLET is determined by your doctor based on your individual medical condition, age, and weight. It is typically taken orally, with or without food, preferably in the evening or at night, and at a consistent time each day to maintain a steady level of medicine in the blood. You should swallow the tablet whole without chewing, crushing, or breaking it.

What are the possible side effects of PENTANERV NT 100 MG TABLET?

Common side effects may include dizziness, drowsiness, fatigue, headache, nausea, vomiting, blurred vision, dry mouth, constipation, difficulty in urination, weight gain, breast enlargement, and tingling sensations. More serious, though less common, side effects can include mood changes, suicidal tendencies, increased heart rate, and uncoordinated body movements. If any side effects persist or worsen, consult your doctor.

Is PENTANERV NT 100 MG TABLET safe during pregnancy or breastfeeding?

PENTANERV NT 100 MG TABLET is generally not recommended during pregnancy unless considered essential by your doctor and the potential benefits outweigh the risks. If taken in the later stages of pregnancy, newborns should be monitored for withdrawal symptoms. For breastfeeding mothers, the medicine can pass into breast milk in small amounts, so it should be used with caution and only if deemed very essential by a healthcare professional.

Can PENTANERV NT 100 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements, as some may interact with PENTANERV NT. Specifically, avoid taking antacids containing aluminum or magnesium within 2 hours of taking this medicine. Caution is also advised with certain medications like MAO inhibitors, buprenorphine, and some cough/cold medicines or anesthetics.

What precautions should be taken while using PENTANERV NT 100 MG TABLET?

Avoid consuming alcohol while taking this medicine, as it can increase dizziness and drowsiness. Do not drive or operate heavy machinery if you experience dizziness, confusion, or disorientation. It is important to monitor your mood and behavior, as this medication may cause changes, including suicidal tendencies; report any unusual changes to your doctor immediately. Inform your doctor if you have kidney, liver, or heart problems, diabetes, pheochromocytoma, bipolar disorder, glaucoma, or a history of seizures.

What happens if a dose of PENTANERV NT 100 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should PENTANERV NT 100 MG TABLET be stored?

Store PENTANERV NT 100 MG TABLET in a cool and dry place, ideally below 30°C, away from direct sunlight and moisture. Keep it out of the sight and reach of children.

Is it safe to stop PENTANERV NT 100 MG TABLET suddenly?

No, you should not stop taking PENTANERV NT 100 MG TABLET suddenly without consulting your doctor. Abrupt discontinuation can lead to withdrawal symptoms such as anxiety, trouble sleeping, excessive sweating, nausea, and pain. Your doctor will likely recommend a gradual reduction in dosage before completely stopping the medication.