Arnoza 50 Mg Tablet (14 Tab)

ARNOZA 50 MG TABLET

ARNOZA 50 MG TABLET is a prescription medicine manufactured by Torrent Pharmaceuticals Ltd.

Composition

ARNOZA 50 MG TABLET contains two active ingredients: Sacubitril (24 mg) and Valsartan (26 mg). This combination is classified as an Angiotensin Receptor Neprilysin Inhibitor (ARNI).

Uses

ARNOZA 50 MG TABLET is primarily used to manage chronic heart failure in adults, particularly in patients with reduced ejection fraction. It helps to relax and widen blood vessels, making it easier for the heart to pump blood, thereby improving heart efficiency and reducing the risk of hospitalization and heart-related complications and death.

Dosage and Administration

This medication should be taken as advised by your physician. It is to be swallowed whole with a glass of water and should not be crushed or chewed. ARNOZA 50 MG TABLET can be taken with or without food, preferably at the same time each day for maximum benefits. The doctor determines the correct dose and duration based on age, body weight, and disease condition.

Side Effects

Common side effects include dizziness, light-headedness (low blood pressure), cough, headache, tiredness, weakness, nausea, diarrhea, and signs of high potassium levels in the blood (e.g., irregular heartbeat, muscle weakness). Serious side effects, though rare, can include severe allergic reactions such as swelling of the face, lips, tongue, or throat (angioedema), and a decrease in renal function.

Precautions

Before taking ARNOZA 50 MG TABLET, inform your doctor if you have liver, kidney, or heart problems, or a history of angioedema. It is contraindicated in pregnant and breastfeeding women. This medicine should not be taken with ACE inhibitors (e.g., enalapril, captopril) and should not be used for at least 36 hours before or after taking an ACE inhibitor. It is also not recommended for use with blood pressure-lowering medicines containing Aliskiren if you have diabetes or impaired kidney function. Caution is advised when driving or operating machinery as it may cause dizziness.

Storage

Store ARNOZA 50 MG TABLET in its original packaging at room temperature (below 30°C or not above 25°C), away from moisture and direct sunlight. Keep it out of the reach and sight of children.

ARNOZA 50 MG TABLET (14 TAB) is a medication primarily used to treat chronic heart failure in adults. It is a combination of two active ingredients, sacubitril and valsartan, which work together to improve heart function and reduce the risk of serious complications.

What is Arnoza 50 MG Tablet used for?

Arnoza 50 MG Tablet is used to manage chronic heart failure with reduced ejection fraction in adults. It helps to relax and widen blood vessels, making it easier for the heart to pump blood, and ultimately reduces the risk of cardiovascular death and hospitalisation due to heart failure.

How does Arnoza 50 MG Tablet work?

Arnoza 50 MG Tablet contains sacubitril and valsartan. Sacubitril inhibits an enzyme called neprilysin, which increases the levels of beneficial peptides that promote blood vessel dilation and improve kidney function. Valsartan is an angiotensin II receptor blocker that blocks the effects of a hormone that causes blood vessels to narrow. By acting together, these components relax blood vessels, reduce strain on the heart, improve its pumping efficiency, and help reduce fluid retention.

What is the usual dosage for Arnoza 50 MG Tablet?

The dosage of Arnoza 50 MG Tablet is determined by your doctor based on your specific condition and response to treatment. It should be taken exactly as prescribed, swallowed whole with a glass of water. It can be taken with or without food, preferably at the same time each day for maximum benefit. Do not crush, chew, or split the tablets.

What are the possible side effects of Arnoza 50 MG Tablet?

Common side effects include low blood pressure (hypotension), high potassium levels (hyperkalaemia), kidney dysfunction, cough, dizziness, diarrhoea, headache, fatigue, nausea, and weakness. Some severe but rare side effects include angioedema, which involves swelling of the face, lips, tongue, or throat. If any side effects are severe or persistent, consult your doctor.

Is Arnoza 50 MG Tablet safe during pregnancy or breastfeeding?

No, Arnoza 50 MG Tablet is contraindicated during pregnancy, especially after the first three months, as it can cause serious harm to the unborn baby. It is also not recommended for use by breastfeeding women. Always inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can Arnoza 50 MG Tablet be taken with other medications?

Arnoza 50 MG Tablet can interact with several medications. It should not be taken with ACE inhibitors (a class of blood pressure medications) due to an increased risk of angioedema and low blood pressure, requiring a 36-hour washout period after stopping an ACE inhibitor before starting Arnoza. It can also interact with other angiotensin receptor blockers (ARBs), aliskiren (especially in patients with diabetes or kidney impairment), potassium-sparing diuretics or potassium supplements (increasing potassium levels), Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), and lithium. Always inform your doctor about all medications, supplements, and herbal products you are taking.

What precautions should be taken while on Arnoza 50 MG Tablet?

Before taking Arnoza 50 MG Tablet, inform your doctor if you have liver disease, severe kidney disease, dehydration, or a history of angioedema. You should limit your salt intake and discuss appropriate physical activity with your doctor. Regular monitoring of blood pressure and kidney function may be advised. Avoid consuming alcohol as it may cause dizziness. If you experience dizziness or tiredness, avoid driving or operating machinery.

What happens if a dose of Arnoza 50 MG Tablet is missed?

If you miss a dose of Arnoza 50 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten tablet.

How should Arnoza 50 MG Tablet be stored?

Arnoza 50 MG Tablet should be stored in its original packaging at room temperature, typically below 30°C (or below 25°C), to protect it from moisture. Keep it out of the reach and sight of children and pets. Do not use the medicine after the expiry date.