Tenepure-m 500 Tablet

TENEPURE-M 500 TABLET

TENEPURE-M 500 TABLET is a medication manufactured by Torrent Pharmaceuticals Ltd., primarily used for the management of type 2 diabetes mellitus. Some formulations may be extended-release (ER).

• Composition TENEPURE-M 500 TABLET contains a combination of two active ingredients: Metformin (500mg) and Teneligliptin (20mg). Metformin, a biguanide, works by reducing glucose production in the liver, decreasing intestinal glucose absorption, and improving the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin levels and reduces glucagon levels in the body, particularly after meals.

• Uses This medicine is prescribed for adults with type 2 diabetes mellitus to improve glycemic control. It is used when diet and exercise alone are insufficient, or when patients have not achieved adequate control with metformin alone or other antidiabetic agents. By effectively controlling blood sugar levels, TENEPURE-M 500 TABLET helps reduce the risk of serious diabetes complications such as kidney damage, eye problems, nerve issues, heart disease, and stroke.

• Dosage and Administration TENEPURE-M 500 TABLET should be taken strictly as prescribed by a physician. It can be consumed with or without food, though taking it with food may help minimize stomach upset. The typical dosage is usually once daily, or as advised by the doctor. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. For optimal benefit, it is recommended to take the medicine regularly at the same time each day. Do not discontinue the medication without consulting your doctor.

• Side Effects

  • Common Side Effects: Nausea, vomiting, diarrhea, headache, stomach ache/upset, respiratory infection, weight gain, sweating, low blood sugar (hypoglycemia), flatulence, altered taste sensations, nasopharyngitis, dizziness, and metallic taste. These generally do not require medical attention and tend to resolve over time.
  • Serious Side Effects: Lactic acidosis (symptoms include cold hands/feet, dizziness, weakness, unusual muscle pain, trouble breathing, severe stomach pain, persistent nausea/vomiting), severe allergic reactions (hives, swelling of face/lips/tongue/throat with difficulty breathing), severe skin rashes, and potential Vitamin B12 deficiency with long-term use. Seek immediate medical attention if these occur.

• Precautions Inform your doctor about any allergies to the medicine's components, or if you have severe kidney or liver impairment, congestive heart failure, severe uncontrollable diabetes, diabetic ketoacidosis, type 1 diabetes, or alcoholism. Caution is advised for pregnant or breastfeeding individuals, and those with pre-existing medical conditions such as heart problems, severe infections, or low potassium levels. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis. Regular monitoring of blood sugar levels and kidney function may be necessary during treatment. Do not drive or operate heavy machinery if you experience vision problems.

• Storage Store TENEPURE-M 500 TABLET in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. Store at or below 25°C or 30°C. Do not use outdated medicine.

What is TENEPURE-M 500 TABLET used for?

TENEPURE-M 500 TABLET is used to treat type 2 diabetes mellitus in adults. It helps manage high blood sugar levels and, when used with a healthy diet and regular exercise, can prevent serious complications of diabetes such as kidney damage, blindness, nerve problems, heart attack, or stroke.

How does TENEPURE-M 500 TABLET work?

This medicine contains two active ingredients: Metformin (500 mg) and Teneligliptin (20 mg).

• Metformin works by decreasing the amount of glucose produced by the liver, reducing the absorption of glucose from the intestines, and improving the body's sensitivity to insulin.
• Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases the release of insulin from the pancreas and lowers the levels of hormones (glucagon) that raise blood sugar. This combined action helps to control both fasting and post-meal blood sugar levels.

What is the usual dosage for TENEPURE-M 500 TABLET?

The dosage of TENEPURE-M 500 TABLET should be taken exactly as prescribed by your doctor. The dose can vary based on individual factors like the severity of your condition and your response to the medication. It is generally recommended to take the tablet with or preferably after meals to help reduce stomach upset. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. Do not stop taking it without consulting your doctor.

What are the possible side effects of TENEPURE-M 500 TABLET?

Common side effects may include diarrhea, nausea, vomiting, abdominal pain or discomfort, flatulence, headache, and a metallic or altered taste sensation. More serious, but rare, side effects can include:

• Lactic acidosis: This is a serious condition with symptoms such as cold hands or feet, dizziness, light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness, or stomach pains.
• Serious allergic reactions: Symptoms include hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing, or severe skin rashes.
• Vitamin B12 deficiency: Long-term use can interfere with Vitamin B12 absorption.

If you experience any severe or persistent side effects, contact your doctor immediately.

Is TENEPURE-M 500 TABLET safe during pregnancy or breastfeeding?

TENEPURE-M 500 TABLET is generally not recommended during pregnancy or breastfeeding. If you are pregnant or planning to become pregnant, or if you are breastfeeding, you should consult your doctor to discuss the potential risks and benefits before taking this medicine.

Can TENEPURE-M 500 TABLET be taken with other medications?

It is crucial to inform your doctor about all other medicines, herbal preparations, and supplements you are taking to avoid potential interactions. TENEPURE-M 500 TABLET can interact with various medications, including:

• Certain heart medicines and diuretics: These can affect how metformin is cleared from your body or increase the risk of lactic acidosis.
• Corticosteroids and other glucose-altering medicines: These can interfere with blood sugar control.
• Iodine contrast medium: Used for X-rays, this may require temporary discontinuation of TENEPURE-M 500 TABLET.
• Alcohol: Avoid consuming alcohol, as it significantly increases the risk of lactic acidosis when taken with this medicine.

What precautions should be taken while using TENEPURE-M 500 TABLET?

Before taking TENEPURE-M 500 TABLET, inform your doctor if you have kidney, liver, or heart disease, problems with your pancreas, or if you consume a lot of alcohol.

• It is not recommended for patients with severe kidney or liver impairment, severe heart failure, diabetic ketoacidosis, or type 1 diabetes.
• Your doctor will likely monitor your blood sugar levels and kidney function regularly during treatment.
• Maintain a healthy diet and engage in regular exercise as recommended by your doctor, as lifestyle plays a significant role in managing diabetes.
• Be aware of symptoms of low blood sugar (hypoglycemia), especially if you are taking other antidiabetic medicines or frequently miss meals. It's advisable to carry sugary food or fruit juice to manage such episodes.
• Report any signs of lactic acidosis, a rare but serious condition, to your doctor immediately.

What happens if a dose of TENEPURE-M 500 TABLET is missed?

If you miss a dose of TENEPURE-M 500 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should TENEPURE-M 500 TABLET be stored?

Store TENEPURE-M 500 TABLET at room temperature, ideally below 30°C. Keep it in a cool, dry place, away from direct sunlight, moisture, and heat. Always ensure the medicine is kept out of the sight and reach of children and pets.