Domstal Dt Tab

DOMSTAL DT TAB

DOMSTAL DT TAB by TORRENT PHARMACEUTICALS LTD is a dispersible tablet formulated to alleviate symptoms of nausea, vomiting, and certain digestive issues.

• Name:

  • Brand Name: DOMSTAL DT TAB
  • Common Name: Domperidone (active ingredient)

• Composition: Each dispersible tablet contains Domperidone I.P. 10mg. Inactive ingredients include lactose, starch, colloidal silicon dioxide, sodium lauryl sulfate, sodium saccharin, talc, strawberry powder flavor, croscarmellose sodium, and magnesium stearate.

• Uses: DOMSTAL DT is primarily prescribed for the treatment of:

  • Nausea and vomiting in adults and adolescents 12 years or older weighing 35 kg or more.
  • Indigestion, including symptoms such as stomach pain, bloating, and a feeling of fullness.
  • Conditions like gastroparesis (slow stomach emptying) and Gastroesophageal Reflux Disease (GERD).
  • Post-operative nausea and vomiting, and those induced by certain medications.

• Dosage and Administration:

  • Take as directed by your doctor.
  • Typically, disperse one tablet in the prescribed amount of water and swallow whole. Do not crush, chew, or break.
  • It is generally advised to take the tablet on an empty stomach, ideally half an hour before meals, as food can delay absorption.
  • The usual dose for adults and adolescents (12 years or older and weighing 35 kg or more) is one 10mg tablet up to three times daily, with a maximum daily dose of 30 mg.
  • The maximum treatment duration should not exceed one week. Do not double a missed dose.

• Side Effects:

  • Common: Dry mouth, headache, stomach pain, and diarrhea. Dizziness and drowsiness may also occur.
  • Serious (Rare): May include heart rhythm disorders (arrhythmia) and cardiac arrest, particularly in elderly patients (over 60 years) or with doses exceeding 30 mg daily.

• Precautions:

  • Cardiac Risks: Use with caution in patients with pre-existing heart conditions. Prolonged use or higher doses may increase the risk of heart rhythm disturbances.
  • Liver/Kidney Impairment: Caution is necessary for patients with liver or kidney disease; dosage adjustments may be required for kidney issues. It is contraindicated in moderate to severe hepatic impairment.
  • Allergies: Do not use if allergic to domperidone or any other ingredients.
  • Drug Interactions: Inform your doctor about all medications, especially certain antifungal agents, antibiotics, and heart medications, as interactions can occur. Avoid simultaneous use with antacids.
  • Pregnancy & Breastfeeding: Generally not recommended during pregnancy. Consult your doctor if breastfeeding, as it should only be used if deemed necessary by a physician.
  • Pediatric Use: Not recommended for children under 12 years of age or adolescents weighing less than 35 kg.
  • Alcohol: Avoid alcohol consumption due to potential for increased drowsiness.
  • Other Contraindications: Should not be used in cases of gastrointestinal hemorrhage, mechanical obstruction, perforation, or in patients with a prolactin-releasing pituitary tumor (prolactinoma).

• Storage: Store in a cool and dry place, protected from direct sunlight and moisture, ideally at temperatures between 10ºC and 25ºC or below 30ºC. Keep out of the sight and reach of children.

DOMSTAL DT TAB is a medicine that contains domperidone as its active ingredient. It is primarily used to relieve symptoms like nausea, vomiting, and indigestion.

Here are some frequently asked questions about DOMSTAL DT TAB:

1. What is DOMSTAL DT TAB used for?

DOMSTAL DT TAB is commonly used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents aged 12 years and older. It also helps in relieving symptoms of indigestion, such as bloating, fullness, and discomfort in the stomach. Additionally, it may be used off-label to help increase breast milk supply in some cases, although this is not an approved use in all regions.

2. How does DOMSTAL DT TAB work?

DOMSTAL DT TAB (domperidone) works by blocking certain receptors in the brain and gut, specifically dopamine receptors. By acting on the chemoreceptor trigger zone in the brain, it helps prevent nausea and vomiting. It also increases the contractions and movement of muscles in the stomach and intestines, which speeds up the emptying of food from the stomach and through the digestive tract, thereby alleviating indigestion symptoms.

3. What is the usual dosage for DOMSTAL DT TAB?

For adults and adolescents 12 years of age and older weighing 35 kg or more, the usual dose is one 10 mg tablet taken up to three times per day. It is generally recommended to take it if possible before meals. The total daily dose should not usually exceed 30 mg, but in some specific cases, a doctor might recommend up to 40 mg per day. Treatment is typically for a short duration, usually not exceeding 7 days.

4. What are the possible side effects of DOMSTAL DT TAB?

Common side effects may include dry mouth, headache, diarrhea, and abdominal cramps. More serious, but rare, side effects can include heart rhythm disorders (like QT prolongation, irregular heartbeat, or even cardiac arrest), especially at higher doses or in individuals over 60 years old. Other uncommon side effects can include swelling of the hands or feet, unusual tiredness, anxiety, drowsiness, breast enlargement or pain, unusual milk discharge, and irregular menstrual periods. Uncontrolled movements, particularly in children, may also occur.

5. Is DOMSTAL DT TAB safe during pregnancy or breastfeeding?

• Pregnancy: There is limited information on its use during pregnancy. It should generally only be used during pregnancy if the anticipated therapeutic benefits justify the potential risks, and if other anti-sickness medicines have not been effective. Always consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.
• Breastfeeding: Small amounts of domperidone pass into breast milk. While it has been used for many years without reported side effects in infants, concerns exist regarding potential cardiac effects in a breastfed baby. Domperidone is not usually recommended during breastfeeding unless your doctor considers it clearly necessary. The FDA has advised against using domperidone to increase milk production due to serious adverse cardiac events.

6. Can DOMSTAL DT TAB be taken with other medications?

Domstal DT TAB can interact with many other medicines. You should not take it if you are taking certain antifungal medications (e.g., oral ketoconazole, fluconazole, voriconazole), some antibiotics (e.g., erythromycin, clarithromycin), certain heart medications (e.g., amiodarone, diltiazem, verapamil), some antidepressants, and medicines for AIDS/HIV. Grapefruit or grapefruit juice can also increase the chance of side effects. Always inform your healthcare provider about all medicines, vitamins, and herbal supplements you are taking.

7. What precautions should be taken while using DOMSTAL DT TAB?

Inform your doctor if you have liver or kidney problems, a history of heart problems (especially rapid, slow, or irregular heartbeats, or QT prolongation), a pituitary gland tumor (prolactinoma), gastrointestinal bleeding, obstruction, or perforation. It is advised to use the lowest effective dose for the shortest possible duration. If you experience symptoms like palpitations, trouble breathing, or loss of consciousness, stop the treatment immediately and consult your doctor. Avoid consuming alcohol while taking this medicine.

8. What happens if a dose of DOMSTAL DT TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

9. How should DOMSTAL DT TAB be stored?

DOMSTAL DT TAB should be stored in a cool, dry place at room temperature, typically below 25°C (77°F), away from heat, moisture, and direct light. Keep the medicine in its original packaging and out of the sight and reach of children. Do not store it in the bathroom or near a sink. Oral suspensions of domperidone prefer room temperature storage as refrigeration can make them more viscous.