Torvate Chrono 200

TORVATE CHRONO 200

TORVATE CHRONO 200 is a medication manufactured by Torrent Pharmaceuticals Ltd.

• Composition: Each tablet contains Sodium Valproate (133.5 mg) and Valproic Acid (58 mg), providing a total valproate equivalent of 200 mg.

• Uses: This medicine is an anticonvulsant primarily used for:

  • Management of epilepsy and various types of seizures, including complex partial seizures, simple and complex absence seizures, and grand mal epilepsy.
  • Treatment of manic episodes associated with bipolar disorder.
  • Prevention of migraine headaches.

• Dosage and Administration: TORVATE CHRONO 200 is for oral administration. It should be swallowed whole with a glass of water and not crushed, chewed, or broken, as it is a controlled-release formulation. It can be taken with or without food, though taking it with food may help minimize stomach upset. The dosage is determined by a doctor based on the patient's condition, age, health, and weight. Do not stop the medication suddenly without consulting your doctor.

• Side Effects:

  • Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, dizziness, tremors, drowsiness/sedation, headache, hair loss, weight gain, gum swelling, and impaired coordination.
  • Serious: Liver damage, pancreatitis, and an increased risk of suicidal thoughts.

• Precautions:

  • Not recommended for individuals with significant liver dysfunction or disease, or hypersensitivity to its components.
  • Pregnancy and Breastfeeding: Can harm an unborn baby (e.g., neural tube defects). Effective contraception is advised for women of child-bearing age. It may also pass into breast milk. Consult your doctor if pregnant or breastfeeding.
  • Alcohol: Avoid alcohol consumption as it can worsen side effects and increase the risk of seizures.
  • Driving/Operating Machinery: May cause dizziness or drowsiness; exercise caution.
  • Inform your doctor about any kidney problems, a history of pancreatitis, or other ongoing medications to avoid potential interactions.
  • Regular monitoring of liver function, blood counts, and valproate levels is crucial during treatment.

• Storage: Store in a cool and dry place, protected from direct sunlight. Keep out of sight and reach of children. Store at room temperature (below 30ºC).

TORVATE CHRONO 200 Tablet CR is a medication manufactured by Torrent Pharmaceuticals Ltd. that contains Sodium Valproate and Valproic Acid. It is primarily used as an anticonvulsant and mood stabilizer.

What is TORVATE CHRONO 200 used for?

TORVATE CHRONO 200 is primarily used to treat epilepsy, which involves managing and controlling various types of seizures or fits. It is also prescribed for controlling manic episodes associated with bipolar disorder and for preventing migraine headaches.

How does TORVATE CHRONO 200 work?

This medication works by decreasing excessive and abnormal nerve activity in the brain. It achieves this by increasing the levels of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter that helps calm down electrical activity in the brain, thereby controlling seizures and stabilizing mood.

What is the usual dosage for TORVATE CHRONO 200?

The dosage of TORVATE CHRONO 200 is determined by your doctor based on your specific condition and response to treatment. It should generally be taken with food to minimize stomach upset. The tablet should be swallowed whole and not crushed or chewed, as this can affect its effectiveness. For epilepsy, typical starting doses are 10-15 mg/kg per day, gradually increased. For bipolar disorder, starting doses might be around 750 mg/day, and for migraines, usually 200 mg to 400 mg per day in divided doses. It may take several weeks to show its full effects.

What are the possible side effects of TORVATE CHRONO 200?

Common side effects can include nausea, vomiting, headache, drowsiness, tremors, hair loss, and weight gain. Some individuals may also experience loss of appetite, gum swelling, vision disturbances, or liver injury. While most side effects are mild and may subside over time, it's important to consult your doctor if they persist or worsen. Serious but rare side effects can include severe pancreatitis or liver problems, indicated by symptoms like yellowing of the skin or eyes, severe abdominal pain, and persistent nausea or vomiting.

Is TORVATE CHRONO 200 safe during pregnancy or breastfeeding?

TORVATE CHRONO 200 is generally considered unsafe during pregnancy due to the definite risk of harm to the developing baby, including potential for congenital disabilities like neural tube defects. Women of child-bearing age should use effective contraception while taking this medication. During breastfeeding, it should be used with caution and only if clearly needed, as small amounts may pass into breast milk. It is important to consult your healthcare provider to assess the risks and benefits.

Can TORVATE CHRONO 200 be taken with other medications?

TORVATE CHRONO 200 can interact with various medications, potentially affecting their levels or increasing the risk of side effects. Inform your doctor about all medicines you are taking, including:

• Other anticonvulsants (e.g., phenytoin, carbamazepine, lamotrigine)
• CNS depressants (e.g., alcohol, barbiturates, benzodiazepines)
• Salicylates (e.g., aspirin)
• Antibiotics (e.g., carbapenems, rifampin, erythromycin)
• Antidepressants (e.g., SSRIs, tricyclics)
• Blood thinners (e.g., warfarin)
• HIV medications (e.g., zidovudine, protease inhibitors like lopinavir and ritonavir)
• Contraceptive pills

What precautions should be taken with TORVATE CHRONO 200?

Several precautions should be observed while taking TORVATE CHRONO 200:

• Medical Conditions: Inform your doctor about any history of kidney or liver problems, meningitis, depression, or suicidal thoughts, as these conditions can impact the medication's efficacy or risk of side effects.
• Alcohol: Avoid alcohol consumption as it can intensify side effects like drowsiness and dizziness and may increase the risk of seizures.
• Driving and Operating Machinery: This medication can cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you.
• Abrupt Discontinuation: Do not stop taking the medication suddenly without consulting your doctor, as this can lead to increased seizure frequency or worsening of bipolar disorder symptoms.
• Monitoring: Regular blood tests may be necessary to monitor your body's response to the drug, including liver function and blood counts.
• Weight Management: Monitor your weight, as this medication can lead to weight gain. A balanced diet and regular exercise are recommended.
• Children: Caution is advised when administering TORVATE CHRONO 200 to children under three years due to a higher risk of liver intoxication.

What happens if a dose of TORVATE CHRONO 200 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should TORVATE CHRONO 200 be stored?

TORVATE CHRONO 200 should be stored in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children and pets. It should be stored at room temperature, ideally between 10ºC to 25ºC or below 30ºC.