Brutacef Dry Syrup

BRUTACEF DRY SYRUP by MANKIND PHARMA LTD

Name

• Common Name: Brutacef Dry Syrup
• Brand Name: BRUTACEF DRY SYRUP (by Mankind Pharma Ltd.)

Composition BRUTACEF DRY SYRUP contains Cefixime as its active ingredient. It is a cephalosporin antibiotic. The typical concentration is 50 mg of Cefixime per 5 ml of reconstituted syrup.

Uses Brutacef Dry Syrup is prescribed for the treatment of various bacterial infections in children. These include:

• Respiratory Tract Infections: Such as bronchitis and pneumonia.
• Ear Infections: Like otitis media.
• Nose and Throat Infections: Including tonsillitis, pharyngitis, and sinusitis.
• Urinary Tract Infections: Affecting the bladder or kidneys.
• Skin and Soft Tissue Infections.
• Uncomplicated Typhoid Fever.
• Certain Sexually Transmitted Diseases: Such as gonococcal urethritis.

This medicine is ineffective against viral infections like the common cold or flu.

Dosage and Administration Brutacef Dry Syrup should be administered as directed by a healthcare professional. To prepare: add boiled and cooled water to the dry powder, shake well, and then top up to the marked level on the bottle. Shake the bottle well before each use. The dosage varies based on body weight and infection severity. It can be given with or without food. However, if stomach upset occurs, it is advisable to administer with food. It is recommended to complete the full course of treatment, typically 7-14 days, even if symptoms improve earlier, to prevent recurrence and resistance. If a dose is missed, administer it as soon as remembered, but do not double the dose if the next scheduled dose is near. If vomiting occurs within 30 minutes of administration, the same dose may be given again.

Side Effects Common side effects may include:

• Diarrhea, loose stools, abdominal pain, flatulence, indigestion.
• Nausea, vomiting.
• Headache, dizziness.
• Rash, itching, hives.

Serious side effects, though rare, warrant immediate medical attention. These include severe allergic reactions (e.g., swelling of face, difficulty breathing), severe uncontrollable watery diarrhea, and unusual bleeding or bruising.

Precautions Caution is advised for patients with a history of allergies, especially to cephalosporin antibiotics or penicillins. Inform your doctor if the child has kidney disease, as dose adjustments may be necessary. Use with caution in children with gastrointestinal issues, particularly colitis. Interactions may occur with medications like carbamazepine and blood thinners such as warfarin. It is not typically recommended for children above 18 years of age.

Storage The dry powder should be stored below 30°C, protected from light and moisture. Once reconstituted, the syrup should be stored in a refrigerator and used within the timeframe specified on the label, typically 7 days. Keep out of reach of children.

What is BRUTACEF DRY SYRUP used for?

BRUTACEF DRY SYRUP is an antibiotic used to treat a variety of bacterial infections in children, typically those between 6 months and 12 years of age. These infections include those affecting the throat (tonsillitis, pharyngitis), ear (otitis media), nasal sinuses (sinusitis), airways and lungs (pneumonia, bronchitis), urinary tract (cystitis, kidney infections), skin and soft tissues, and gastrointestinal tract. It is also used to manage uncomplicated typhoid fever. This medicine is not effective against viral infections like the common cold or flu.

How does BRUTACEF DRY SYRUP work?

BRUTACEF DRY SYRUP contains Cefixime, which belongs to a class of antibiotics called cephalosporins. Cefixime works by inhibiting the formation and growth of the bacterial cell wall, a protective covering essential for the bacteria's survival. By disrupting this process, it effectively kills the bacteria responsible for the infection and prevents their further growth and multiplication.

What is the usual dosage for BRUTACEF DRY SYRUP?

The dosage of BRUTACEF DRY SYRUP is determined by a doctor based on the child's body weight, the type and severity of the infection, and their response to the medication. It is crucial to administer the medicine exactly as prescribed by your doctor and to complete the full course of treatment, even if the symptoms improve earlier, to prevent the infection from returning or becoming harder to treat. The medicine is typically prescribed for 7 to 14 days.

How should BRUTACEF DRY SYRUP be prepared and administered?

To prepare the dry syrup, add boiled and cooled water to the dry powder in the bottle. Shake the bottle thoroughly, and then fill it up to the mark indicated on the bottle. Shake the reconstituted solution well before each use to ensure the medicine is evenly mixed. BRUTACEF DRY SYRUP can be taken with or without food. However, if your child experiences stomach upset, it is advisable to give it with food.

What are the possible side effects of BRUTACEF DRY SYRUP?

Common side effects may include nausea, vomiting, abdominal pain, indigestion, gas, headache, dizziness, rash, itching, and diarrhea. Most of these effects are usually mild and temporary. If diarrhea is severe, watery, or bloody, or if any side effects persist or worsen, contact your doctor immediately. Seek immediate medical attention for signs of a severe allergic reaction such as skin rash, swelling of the face, lips, throat, or tongue, or difficulty breathing.

Is BRUTACEF DRY SYRUP safe during pregnancy or breastfeeding?

When prescribed by a doctor, BRUTACEF DRY SYRUP is generally considered safe for use during pregnancy, with studies indicating low or no adverse effects on the developing baby. It is also considered safe for use during breastfeeding, as studies suggest the drug does not pass into breastmilk in significant amounts that would harm the baby. However, infants should be monitored for potential side effects like diarrhea or yeast infection, and prolonged use should be avoided.

Can BRUTACEF DRY SYRUP be taken with other medications?

BRUTACEF DRY SYRUP can interact with certain medications. For example, its effect may increase when taken with blood thinners like warfarin, raising the risk of bleeding. Iron supplements and antacids can decrease the absorption of cefixime, so doses should be separated by at least 2 hours. Carbamazepine, used for fits, should be used cautiously. Oral contraceptives may have reduced effectiveness. Always inform your doctor about all other medicines, herbal preparations, and supplements your child is taking to avoid potential interactions.

What precautions should be taken while using BRUTACEF DRY SYRUP?

Do not use BRUTACEF DRY SYRUP if your child is allergic to Cefixime or any other cephalosporin or penicillin antibiotics. Caution is advised for children with kidney disease, and a dose adjustment may be necessary. It should also be used with caution in patients with liver disease or gastrointestinal diseases, especially colitis. BRUTACEF DRY SYRUP is not for viral infections.

What happens if a dose of BRUTACEF DRY SYRUP is missed?

If a dose is missed, administer it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to compensate for a missed one, as this can increase the risk of side effects. If your child vomits within 30 minutes of taking a dose, give the same dose again, ensuring not to double dose if the next scheduled dose is due soon.

How should BRUTACEF DRY SYRUP be stored?

The dry powder should be stored at a temperature not exceeding 25°C, protected from light and moisture. Once reconstituted, the suspension should be stored in the refrigerator. The reconstituted solution must be used within 7 days (or as specified on the bottle label), and any unused portion should be discarded after this period. Keep the medicine out of reach of children.