Xafinact 50 Mg Tablet (10 Tab)

XAFINACT 50 MG TABLET

XAFINACT 50 MG TABLET is a medication used in the management of Parkinson's disease, manufactured by Sun Pharmaceutical Industries Ltd..

• Name: Xafinact 50 MG TABLET (Brand Name), Safinamide (Common Name).
• Composition: Each tablet contains Safinamide 50 mg as the active ingredient. Safinamide belongs to a class of medications known as monoamine oxidase type B (MAO-B) inhibitors.
• Uses: Xafinact 50 MG TABLET is primarily prescribed for adults to treat Parkinson's disease. It helps manage symptoms such as tremors, muscle stiffness, slowed movements, and difficulty with balance and coordination. It works by increasing the levels of dopamine, a crucial neurotransmitter for movement control, in the brain. This medication is often used as an add-on therapy with other anti-Parkinson's medications to enhance their effectiveness.
• Dosage and Administration: The typical starting dose for adults is 50 mg once daily, taken orally. It can be taken with or without food, but it is recommended to take it at the same time each day for consistent blood levels. Tablets should be swallowed whole with water and not chewed, crushed, or broken. The dosage and duration of treatment are determined by a healthcare professional. If a dose is missed, it should be skipped, and the regular schedule resumed; a double dose should not be taken.
• Side Effects: Common side effects may include cough, flu-like symptoms, insomnia (difficulty sleeping), involuntary muscle movement, falls, nausea, dizziness, and headache. Less common side effects can involve orthostatic hypotension (sudden drop in blood pressure upon standing). Serious but rare side effects include signs of hypertensive crisis, neuroleptic malignant syndrome, and serotonin syndrome.
• Precautions: Xafinact 50 MG TABLET is not recommended for use during pregnancy or breastfeeding. It is also contraindicated in individuals with certain eye conditions such as albinism, retinal degeneration, uveitis, inherited retinopathy, or severe progressive diabetic retinopathy. Caution should be exercised in patients with conditions like schizophrenia, bipolar disorder, high or low blood pressure, dyskinesia, or sleep problems. Individuals with liver or kidney impairment should use this medication with caution, and dose adjustments may be necessary. Concomitant use with other MAO inhibitors, antidepressants, or opioid drugs can increase the risk of serotonin syndrome. It is advisable to avoid alcohol. A high-protein diet should be reduced or avoided as it may cause an unsafe rise in blood pressure. This medication may cause decreased alertness, affect vision, or lead to drowsiness and dizziness; therefore, caution is advised when driving or operating machinery.
• Storage: Xafinact 50 MG TABLET should be stored at a controlled room temperature, typically between 20°C to 25°C. It should be kept away from moisture, heat, and light, and should not be frozen. Keep out of sight and reach of children and pets.

XAFINACT 50 MG TABLET contains Safinamide and is primarily used in the management of Parkinson's disease.

Here are some frequently asked questions about XAFINACT 50 MG TABLET:

What is XAFINACT 50 MG TABLET used for?

XAFINACT 50 MG TABLET is primarily used to treat Parkinson's disease in adults. It helps manage symptoms such as tremors, stiffness, slowed movements, and difficulty with balance and coordination. It can be used alone or in combination with other anti-Parkinson's medications like Levodopa.

How does XAFINACT 50 MG TABLET work?

XAFINACT 50 MG TABLET contains Safinamide, which belongs to a class of medicines called Monoamine Oxidase type B (MAO-B) inhibitors. It works by increasing the levels of dopamine in the brain. Dopamine is a chemical messenger crucial for controlling movement, and its levels are typically low in individuals with Parkinson's disease. By inhibiting the breakdown of dopamine, Safinamide helps improve motor function and reduces symptoms.

What is the usual dosage for XAFINACT 50 MG TABLET?

The usual starting dose for adults is 50 mg once daily. Your doctor may adjust the dose based on your response and needs, with the maximum recommended dose typically being 100 mg daily. It can be taken with or without food, but it is often advised to take it at the same time each day, preferably in the morning, to maintain consistent levels in the body.

What are the possible side effects of XAFINACT 50 MG TABLET?

Common side effects include insomnia (difficulty sleeping), involuntary muscle movements, feeling sleepy or dizzy, falls, headache, clouding of the eye lens, a drop in blood pressure upon standing (orthostatic hypotension), and nausea. If any side effects worsen or persist, it is advisable to consult your doctor.

Is XAFINACT 50 MG TABLET safe during pregnancy or breastfeeding?

XAFINACT 50 MG TABLET is generally not recommended for use during pregnancy or for women planning pregnancy. It is also not recommended for breastfeeding women, as it may pass into breast milk and potentially harm the baby. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can XAFINACT 50 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including prescription, over-the-counter drugs, nutritional supplements, and herbal products. XAFINACT 50 MG TABLET should not be used concurrently or within 14 days of discontinuing other Monoamine Oxidase (MAO) inhibitors, certain antidepressants (like fluoxetine, fluvoxamine, venlafaxine, duloxetine), or opioid drugs, as this can lead to serious drug interactions such as serotonin syndrome or hypertensive crisis.

What precautions should be taken with XAFINACT 50 MG TABLET?

Exercise caution if you have kidney or liver problems, as dose adjustments may be needed. It is not recommended for individuals with certain eye conditions such as albinism, retinal degeneration, uveitis, or inherited retinopathy. The medicine may cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you. Also, a high-protein diet may interact with XAFINACT, potentially causing an unsafe rise in blood pressure, so a reduced or avoided high-protein diet may be suggested.

What happens if a dose is missed?

If you miss a dose of XAFINACT 50 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should XAFINACT 50 MG TABLET be stored?

XAFINACT 50 MG TABLET should be stored at a controlled room temperature, typically between 20°C to 25°C. Keep it away from moisture, heat, and direct sunlight. It should not be frozen and must be kept out of reach of children and pets.