Motinorm Syrup

Here is the detailed product description for Motinorm Syrup:

Motinorm Syrup by Medley Pharmaceuticals

• Name: Motinorm Syrup (Common name), Motinorm Syrup (Brand name)
• Composition:
  • The active ingredient is Domperidone, typically found at a concentration of 1mg/ml or 5mg/5ml.
• Uses:
  • Motinorm Syrup is primarily used to treat nausea, vomiting, and indigestion.
  • It is also prescribed for heartburn, gastroesophageal reflux disease (acid reflux), and the sensation of fullness caused by delayed gastric emptying.
  • Other uses include treating symptoms of vertigo, motion sickness, and dizziness.
  • In children, it helps alleviate indigestion, gastroesophageal reflux disease, nausea, and vomiting.
  • Occasionally, domperidone may be used to enhance milk production.
• Dosage and Administration:
  • Motinorm Syrup should be taken before meals as directed by a doctor.
  • It is crucial to follow the prescribed dose and duration.
  • If symptoms do not resolve within 3-4 days, consult a doctor and do not continue use for longer than seven days without medical advice.
• Side Effects:
  • Common: Dry mouth, drowsiness, headache, stomach cramp, indigestion, nausea, sleepiness, and potential weight gain.
  • Serious (with excessive intake or prolonged use): Irregular heartbeats, heart block, agitation, confusion. Prolonged intake may increase the risk of heart rhythm disorder (arrhythmia) and cardiac arrest, particularly in the elderly (over 60 years) or with doses exceeding 30 mg daily. Other less common side effects can include loss of balance, swelling of the mouth, breast milk discharge, male breast swelling, menstrual irregularities, breast pain, and constipation.
• Precautions:
  • Do not mix Motinorm Syrup with herbal or ayurvedic medicines.
  • Consult your doctor if you have liver or kidney problems, a pituitary gland tumor, cardiac disease, or abnormal levels of magnesium, potassium, or calcium in your blood. Severe liver impairment may contraindicate its use.
  • Exercise caution if you have serious intestinal issues such as bleeding, obstruction, or perforation.
  • It is not generally recommended for children under 12 years of age without specific medical guidance.
  • Avoid driving or operating heavy machinery if you experience dizziness.
  • Inform your doctor if you are pregnant or breastfeeding.
  • Do not exceed the prescribed dose.
  • Avoid consuming grapefruit or grapefruit juice while taking this medicine.
• Storage:
  • Store below 30°C.
  • Keep in a cool, dry place away from direct sunlight and moisture.
  • Ensure it is kept out of sight and reach of children.

Motinorm Syrup, manufactured by Medley Pharmaceuticals, contains domperidone as its active ingredient. It is primarily used to relieve symptoms of nausea and vomiting.

Here are some frequently asked questions about Motinorm Syrup:

1. What is Motinorm Syrup used for?

Motinorm Syrup is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. It also helps in treating indigestion, gastroesophageal reflux disease (GERD), and symptoms related to slow stomach emptying (gastroparesis). In some cases, it may also be prescribed for motion sickness and vertigo.

2. How does Motinorm Syrup work?

Motinorm Syrup contains domperidone, which works as a dopamine antagonist. It blocks certain receptors (like dopamine and serotonin) in the brain's vomiting center (chemoreceptor trigger zone – CTZ), which helps prevent nausea and vomiting. Additionally, it acts as a prokinetic agent, increasing the movement and emptying of the upper gastrointestinal tract, thereby reducing stomach emptying time and relieving symptoms like bloating and fullness.

3. What is the usual dosage of Motinorm Syrup?

The dosage of Motinorm Syrup should be taken as prescribed by your doctor. It is generally recommended to take it orally, preferably 15-30 minutes before meals, on an empty stomach, for optimal absorption. For adults and adolescents over 12 years old and weighing more than 35 kg, a typical dose is 10 ml (equivalent to 10 mg of domperidone) up to three times daily, with a maximum daily dose not exceeding 30 ml. For children under 12 years or weighing less than 35 kg, the dose is calculated individually by a doctor based on body weight, and its use should be under strict medical supervision. The medication should not be used for longer than seven days without physician approval.

4. What are the possible side effects of Motinorm Syrup?

Common side effects include dry mouth, headache, drowsiness, stomach cramps, and diarrhea. These are usually temporary and may resolve as your body adjusts. More serious, but less common, side effects can include irregular heartbeats (arrhythmia) and, rarely, cardiac arrest, especially in elderly patients or those taking doses higher than 30 mg daily. Allergic reactions like itching, rash, or swelling may also occur. If you experience palpitations, trouble breathing, or loss of consciousness, contact a doctor immediately.

5. Is Motinorm Syrup safe during pregnancy or breastfeeding?

Motinorm Syrup is generally not recommended during pregnancy unless specifically advised by a doctor, as there are limited human studies and animal studies have shown potential harmful effects on the developing baby. For breastfeeding mothers, it is usually not recommended as domperidone passes into breast milk in small amounts and may cause unwanted side effects in the infant. It should only be used if your physician considers it necessary, for example, to increase milk supply, and the benefits outweigh the risks.

6. Can Motinorm Syrup be taken with other medications?

Motinorm Syrup can interact with other medications. It is important to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions. Particular caution is advised with anti-fungal medicines, heart-related medicines, certain antibiotics (like macrolides), cancer treatments, and medications for mental health problems. Combining it with alcohol may cause increased sleepiness or an irregular heartbeat. Opioid analgesics and antimuscarinics may also antagonize its prokinetic effects.

7. What precautions should be taken while using Motinorm Syrup?

Do not take Motinorm Syrup if you are allergic to domperidone or any other components. Inform your doctor if you have liver or kidney problems, as dosage adjustments may be necessary. It should be used with caution in elderly patients (over 60 years) and is generally not recommended for adolescents weighing less than 35 kg or children under 12 years of age, except under strict medical supervision for specific conditions. Patients with pre-existing heart conditions, a history of heart rhythm disorders, or low levels of potassium or magnesium should use it with caution, as it can increase the risk of heart problems. Avoid it if you have gastrointestinal bleeding, obstruction, or perforation, or a pituitary gland tumor (prolactinoma).

8. What happens if a dose of Motinorm Syrup is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

9. How should Motinorm Syrup be stored?

Motinorm Syrup should be stored at room temperature, in a cool and dry place, away from direct heat and light. Keep it in its original packaging and ensure it is out of the reach and sight of children and pets. The temperature should ideally be below 30°C.