Tramazac Inj1mlsingle

TRAMAZAC INJ1MLSINGLE is an injectable medication manufactured by Zydus Healthcare Limited, primarily used for pain management.

• Name:

  • Brand Name: Tramazac
  • Common Name: Tramadol Hydrochloride Injection

• Composition:

  • Active Ingredient: Tramadol Hydrochloride 50 mg/ml

• Uses: TRAMAZAC INJ1MLSINGLE is prescribed for the effective relief of moderate to severe pain. It is used to manage various conditions including:

  • Chronic pain requiring continuous treatment
  • Post-operative pain
  • Cancer-related pain
  • Pain caused by traumatic injury
  • Pain associated with conditions like fibromyalgia, osteoarthritis, and rheumatoid arthritis

• Dosage and Administration: This medicine is administered by a doctor or healthcare professional and should not be self-administered. It can be given via intramuscular (IM), slow intravenous (IV) injection or infusion, or subcutaneous (SC) routes. The usual dose for adults and adolescents over 12 years is 50 mg or 100 mg every 4-6 hours. The total daily dose should not exceed 400 mg, except in special clinical circumstances like severe post-operative or cancer pain. Dosage adjustments may be necessary for elderly patients or those with renal or hepatic impairment.

• Side Effects: Common side effects include:

  • Nausea, vomiting, constipation, dry mouth
  • Sleepiness, drowsiness, dizziness, headache
  • Sweating
  • Pain at the injection site, heartburn, stomach pain, redness, and diarrhea Serious side effects can include respiratory depression and an increased risk of seizures. Long-term use or high doses may lead to dependency and withdrawal symptoms if stopped abruptly.

• Precautions: Inform your doctor about any existing heart, liver, or kidney problems, or a history of seizures. This medicine is not recommended for individuals with uncontrolled epilepsy, severe respiratory depression or asthma, or those consuming alcohol or other CNS depressants. It is also not recommended for pregnant or breastfeeding women, or children under 12 years, especially those with breathing problems. Avoid driving or operating machinery if you experience drowsiness or dizziness.

• Storage: Store in a cool and dry place, away from direct sunlight. Keep the vials at room temperature, typically between 20°C to 25°C, or below 30°C. Keep out of reach of children and pets.

What is Tramazac Injection used for?

Tramazac Injection is primarily used to relieve moderate to severe chronic pain that requires continuous treatment. It is effective for conditions such as chronic pain, post-operative pain, cancer-related pain, pain from traumatic injuries, fibromyalgia, osteoarthritis, and rheumatoid arthritis.

How does Tramazac Injection work?

Tramazac Injection contains tramadol, an opioid analgesic. It works by mimicking the action of natural pain-reducing chemicals called endorphins in the brain and spinal cord, thereby blocking the transmission of pain signals to the brain. Additionally, it enhances the effects of serotonin and noradrenaline, which are chemical messengers in the brain and spinal cord that further aid in pain relief.

What is the usual dosage of Tramazac Injection?

Tramazac Injection must be administered by a healthcare professional; it should not be self-administered. The dose and duration of treatment are determined by your doctor based on your specific condition and how you respond to the medicine. For adults, a common dosage is 50-100 mg every 4 to 6 hours as needed, with a maximum daily dose typically not exceeding 400 mg.

What are the possible side effects of Tramazac Injection?

Common side effects may include nausea, constipation, dry mouth, sleepiness, dizziness, vomiting, headache, and sweating. Less common side effects can include pain at the injection site, heartburn, stomach pain, redness, and diarrhea. If these side effects persist or worsen, you should inform your doctor immediately. More serious, but rare, side effects can include respiratory depression (slowed breathing) and seizures.

Is Tramazac Injection safe during pregnancy or breastfeeding?

Pregnancy: Tramazac Injection (tramadol) is generally not recommended during pregnancy, particularly towards the end, due to insufficient safety data and the potential for neonatal opioid withdrawal syndrome in the baby. However, for some pregnant women with severe pain, a doctor might consider it the best option, especially in the second and third trimesters for occasional doses. Your doctor will determine the best course of action.

Breastfeeding: Small amounts of tramadol pass into breast milk. If your doctor determines your baby is healthy, Tramazac Injection may be used for a short period while breastfeeding. It's crucial to monitor the infant for any signs of increased sleepiness, difficulty feeding, or breathing problems. The US FDA recommends against its use during breastfeeding due to potential risks to the infant.

Can Tramazac Injection be taken with other medications?

Tramazac Injection has many potential drug interactions (over 700 reported), some of which can be significant. It is crucial to inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. You should avoid alcohol consumption during treatment, as it can increase drowsiness and the risk of side effects. Special caution is advised with other opioids, antidepressants (e.g., SSRIs like Lexapro, MAO inhibitors), antipsychotics, sedatives, carbamazepine, and ondansetron. Combining these can increase the risk of serious side effects like serotonin syndrome or seizures.

What precautions should be taken while using Tramazac Injection?

Do not self-administer Tramazac Injection. Inform your doctor if you have any existing heart, liver, or kidney problems, as dosage adjustments may be necessary. Tramazac Injection can cause drowsiness, dizziness, and blurred vision; therefore, avoid driving or operating heavy machinery until you know how the medicine affects you. It should be used with caution in individuals with respiratory issues, a history of substance abuse, head injury, increased intracranial pressure, or gastrointestinal obstruction. It is generally not recommended for children under 12 years of age, and not for those under 18 years if they have had tonsil or adenoid removal.

What happens if a dose of Tramazac Injection is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

How should Tramazac Injection be stored?

Tramazac Injection should be stored in a cool and dry place, away from direct sunlight, and out of the reach and sight of children. It is generally recommended to store it below 25°C or 30°C.