Cardace Am 10 Tablet

CARDACE AM 10 TABLET

CARDACE AM 10 TABLET, manufactured by SANOFI INDIA LIMITED, is a combination medication primarily used for managing cardiovascular conditions.

• Name: Cardace AM 10 Tablet

• Composition: Each tablet contains Amlodipine 5 mg and Ramipril 10 mg.

• Uses:

  • Management of hypertension (high blood pressure).
  • Treatment of certain types of angina (chest pain), including Prinzmetal or variant angina.
  • Management of heart failure and reduction of hospitalization risk in heart patients.
  • Protection of kidney function, especially in patients with both hypertension and type II diabetes mellitus.

• Dosage and Administration:

  • Typically, one tablet is taken once daily.
  • It can be taken with or without food.
  • It is recommended to take the tablet at the same time each day.
  • Swallow the tablet whole with a sufficient amount of liquid; do not chew or crush it.
  • Dose adjustments, if needed, should be made at intervals of 2 or 3 weeks.
  • The maximum recommended daily dose for ramipril is 10 mg and for amlodipine is 10 mg.

• Side Effects:

  • Common: Dizziness, swelling of ankles or other body parts (edema), headache, sleepiness, tiredness, racing heartbeat (palpitations), indigestion, constipation, muscle cramps, dry cough, flushing (redness and warmth of the skin), nausea, diarrhea, stomach pain, blurred vision, and increased potassium levels in the blood.
  • Serious: Signs of allergic reactions (e.g., skin rash, swelling of the face, lips, mouth or throat leading to difficulty in breathing or swallowing), severe skin reactions (e.g., blistering and peeling of skin), chest pain or shortness of breath (signs of heart attack), and inflammation of the pancreas (severe stomach pain radiating to the back).

• Precautions:

  • Not recommended for use in patients with severe hypotension (low blood pressure), pregnancy, or breastfeeding.
  • Use with caution in patients with liver or kidney problems, severe heart problems (such as aortic stenosis or cardiogenic shock), recent heart attack, low salt diet, diabetes, or severe dehydration.
  • Avoid alcohol consumption as it may increase the risk of side effects.
  • Consumption of grapefruit juice is not recommended due to increased risk of severe adverse effects.
  • Avoid potassium-rich foods or supplements as the medicine may increase potassium levels in the blood.
  • Regular monitoring of blood pressure, kidney function, and electrolyte levels is advised during treatment.
  • This medicine may cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.

• Storage:

  • Store below 25°C or 30°C in a cool and dry place.
  • Keep out of the sight and reach of children and pets.

What is CARDACE AM 10 TABLET used for?

CARDACE AM 10 TABLET is primarily used to manage hypertension (high blood pressure). It is also prescribed for certain types of angina (chest pain), such as Prinzmetal or variant angina. Additionally, it helps in managing heart failure, reducing the chances of hospitalization, and protecting kidney function, particularly in patients with both hypertension and type II diabetes mellitus.

How does CARDACE AM 10 TABLET work?

CARDACE AM 10 TABLET is a combination medication containing Amlodipine and Ramipril. Amlodipine, a calcium channel blocker, relaxes the blood vessels by preventing calcium from entering their walls. This action improves blood flow, reduces the heart's workload, and increases oxygen supply to heart muscles. Ramipril, an ACE (angiotensin-converting enzyme) inhibitor, works by blocking the production of angiotensin II, a substance that constricts blood vessels, and by preventing the breakdown of bradykinin, which promotes vasodilation. Together, these two components relax and widen blood vessels, leading to lower blood pressure and improved heart and kidney function.

What is the usual dosage for CARDACE AM 10 TABLET?

The usual dosage is one tablet once daily. CARDACE AM 10 TABLET contains Amlodipine 5 mg and Ramipril 10 mg. It can be taken with or without food, but it is best to take it at the same time each day to maintain consistent blood levels. Your doctor will determine the appropriate dose and duration of treatment based on your medical condition and response to the medication. Dosage adjustments, if needed, should occur at intervals of 2 or 3 weeks.

What are the possible side effects of CARDACE AM 10 TABLET?

Common side effects may include dizziness, swelling of ankles or other body parts (edema), headache, sleepiness, tiredness, racing heartbeat (palpitations), flushing (redness and warmth of the skin), indigestion, constipation, stomach pain, muscle cramps, and a dry cough.

More serious but rare side effects that require immediate medical attention include signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat, which can lead to difficulty in breathing or swallowing), severe skin reactions (blistering and peeling of skin), chest pain or shortness of breath (signs of a heart attack), or inflammation of the pancreas (severe stomach pain radiating to the back). CARDACE AM 10 TABLET may also increase potassium levels in the blood, so regular monitoring may be advised.

Is CARDACE AM 10 TABLET safe during pregnancy or breastfeeding?

CARDACE AM 10 TABLET is not recommended for use during pregnancy as it may cause serious harm to the developing fetus and is contraindicated in the last 6 months of pregnancy. It is also not recommended for use in breastfeeding women. It is crucial to consult your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medication.

Can CARDACE AM 10 TABLET be taken with other medications?

It is essential to inform your doctor about all prescription, non-prescription medications, supplements, and herbal products you are taking. CARDACE AM 10 TABLET can interact with several medications, including:

• Potassium-sparing diuretics (e.g., spironolactone, triamterene), potassium supplements, trimethoprim-containing antibiotics, and heparin, which can increase the risk of high potassium levels in the blood.
• Other blood pressure-lowering medications (e.g., ARBs, diuretics, beta-blockers) may lead to an increased risk of low blood pressure.
• NSAIDs (e.g., ibuprofen, naproxen) may reduce the antihypertensive effect and increase the risk of kidney problems.
• Sacubitril/valsartan is contraindicated with this medication.
• Lithium salts, tacrolimus, and cyclosporine may require careful monitoring and dose adjustments.
• Medicines for diabetes/insulin may increase the risk of low blood sugar.
• Grapefruit juice should be avoided as it can significantly lower blood pressure to abnormal levels.
• Alcohol consumption is unsafe with CARDACE AM 10 TABLET as it can increase the risk of low blood pressure.

What precautions should be taken while taking CARDACE AM 10 TABLET?

Before taking CARDACE AM 10 TABLET, inform your doctor if you have any liver or kidney problems, severe high or low blood pressure, or other heart conditions such as narrowing of the arteries, cardiogenic shock, or a recent heart attack. Caution is advised if you are on a low-salt diet or are severely dehydrated. Regular monitoring of blood pressure, kidney function, and electrolyte levels (especially potassium) is recommended during treatment. This medication may cause dizziness or tiredness, so avoid driving or operating machinery until you know how it affects you. Do not stop taking CARDACE AM 10 TABLET without consulting your doctor, as hypertension often requires long-term management.

What happens if a dose of CARDACE AM 10 TABLET is missed?

If you miss a dose of CARDACE AM 10 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should CARDACE AM 10 TABLET be stored?

CARDACE AM 10 TABLET should be stored below 25°C or 30°C in a cool and dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets.