Stalix D 100+10

Here is a detailed product description for STALIX D 100+10 by TORRENT PHARMACEUTICALS LTD:

STALIX D 10+100 Tablet

Name

• Brand Name: STALIX D 10+100 Tablet
• Common Names: Dapagliflozin and Sitagliptin

Composition STALIX D 10+100 Tablet contains a combination of two active ingredients:

• Dapagliflozin: 10 mg
• Sitagliptin: 100 mg

Uses STALIX D 10+100 Tablet is primarily used for the management of type 2 diabetes mellitus in adults. It is prescribed to improve blood sugar control in conjunction with diet and exercise, especially when metformin monotherapy is insufficient or inappropriate. Additionally, it may help reduce the risk of cardiovascular events such as heart attack and heart failure, and can also offer protection against kidney damage in adults with type 2 diabetes and established cardiovascular disease or chronic kidney disease.

Dosage and Administration

• Take STALIX D 10+100 Tablet as advised by a healthcare professional.
• Swallow the tablet whole with a glass of water; do not crush or chew it.
• It can be taken with or without food, preferably at the same time each day to maintain consistent blood sugar control.
• Do not alter the dose or discontinue the medication without consulting your doctor.

Side Effects Common Side Effects:

• Genital mycotic infections (yeast or fungal infections in the genital area)
• Urinary tract infections (UTIs)
• Upper respiratory tract infections, nasopharyngitis (cold-like symptoms, runny nose, sore throat)
• Headache
• Increased urination
• Flatulence, constipation, stomach pain, diarrhea
• Dizziness
• Swelling of hands or legs
• Dry mouth

Serious Side Effects (Seek immediate medical attention if experienced):

• Inflamed pancreas (pancreatitis), characterized by severe and persistent stomach pain with or without nausea and vomiting.
• Serious allergic reactions (rash, hives, blisters, swelling of lips, tongue, face, throat, difficulty breathing/swallowing).
• Diabetic ketoacidosis (increased ketone levels, nausea, vomiting, stomach ache, excessive thirst, confusion, sweet-smelling breath).
• Low blood sugar levels (hypoglycemia), especially when used with insulin or insulin secretagogues.

Precautions

• Pregnancy: STALIX D 10+100 Tablet is contraindicated during pregnancy.
• Breastfeeding: Caution is advised if breastfeeding, and consultation with a doctor is recommended due to limited data.
• Alcohol: Exercise caution with alcohol consumption as it may affect blood sugar levels.
• Kidney/Liver Issues: Caution is advised in patients with liver health issues or a history of kidney problems. It is not recommended for severe kidney problems or those on dialysis.
• Pancreatitis: Use with caution in patients with a history of pancreatitis.
• Hydration & Hygiene: Drink plenty of fluids to prevent dehydration and practice good hygiene to prevent genital fungal and urinary tract infections.
• Drug Interactions:
  • May increase the risk of low blood pressure when taken with diuretics or antihypertensive medications.
  • Certain medications like carbamazepine or rifampicin may reduce the effectiveness of sitagliptin.
  • When used with insulin or insulin secretagogues, there is an increased risk of hypoglycemia; dosage adjustment may be necessary.

Storage

• Store STALIX D 10+100 Tablet at room temperature, typically between 20°C to 25°C, or below 30°C.
• Keep the medicine in its original package, protected from moisture and direct sunlight.
• Ensure the medicine is kept out of reach of children.
• Do not use the medicine beyond its expiry date.

What is STALIX D 100+10 used for?

STALIX D 100+10 Tablet is primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone, or when metformin monotherapy, are not enough to control blood sugar levels. This medicine helps improve blood sugar control and can also reduce the risk of serious diabetes complications such as kidney damage, eye damage, nerve problems, and cardiovascular events.

How does STALIX D 100+10 work?

STALIX D 100+10 contains two active ingredients: Dapagliflozin (10 mg) and Sitagliptin (100 mg). Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by preventing your kidneys from reabsorbing glucose back into your body, instead removing excess sugar through urine. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases certain natural hormones (incretins) which stimulate insulin production after meals and reduce glucose produced by the liver. Together, these actions help to lower blood sugar levels.

What is the usual dosage for STALIX D 100+10?

The dosage of STALIX D 100+10 is determined by your doctor based on your medical condition and response to treatment. It is typically taken once daily, with or without food, preferably at the same time each day to maintain consistent blood sugar control. The tablet should be swallowed whole with water and not crushed, chewed, or broken.

What are the possible side effects of STALIX D 100+10?

Common side effects may include genital mycotic (yeast or fungal) infections, urinary tract infections, upper respiratory tract infections (like cold symptoms or nasopharyngitis), headache, and increased urination. Some individuals might also experience dizziness or low blood sugar (hypoglycemia), especially when taken with other antidiabetic medicines. Serious but less common side effects can include pancreatitis or diabetic ketoacidosis. If you experience persistent or worsening side effects, consult your doctor.

Is STALIX D 100+10 safe during pregnancy or breastfeeding?

STALIX D 100+10 is contraindicated during pregnancy. It should not be used if you are pregnant or planning to conceive. Caution is advised while taking this medicine if you are breastfeeding due to limited available data. Always consult your doctor before using this medication if you are pregnant or breastfeeding.

Can STALIX D 100+10 be taken with other medications?

STALIX D 100+10 can interact with certain medications. For example, taking it with diuretics or other antihypertensive medicines may increase the risk of low blood pressure. Strong CYP3A4 or P-gp inducers (like carbamazepine or rifampicin) may reduce its effectiveness. When taken with insulin or insulin secretagogues (such as glimepiride), it may increase the risk of low blood sugar. Always inform your doctor about all prescription, over-the-counter, herbal, and supplement medications you are currently taking or plan to take to avoid potential interactions.

What precautions should be taken while using STALIX D 100+10?

• Kidney and Liver Health: Exercise caution if you have kidney or liver problems. Your doctor may adjust your dose or recommend against its use, especially with severe kidney issues or if you are on dialysis.
• Alcohol Consumption: Avoid excessive alcohol intake as it can affect your blood sugar levels and may increase the risk of diabetic ketoacidosis.
• Dehydration: This medicine can cause increased urination, potentially leading to dehydration. Ensure you drink plenty of fluids to stay hydrated.
• Hypoglycemia: If you are also taking insulin or other medicines that lower blood sugar, you might be at a higher risk of hypoglycemia (low blood sugar). Be aware of symptoms like sweating, anxiety, fast heartbeat, hunger, headache, and carry a source of sugar.
• Hygiene: Maintain good personal hygiene, especially in the genital area, to help prevent fungal infections, which are a possible side effect.

What happens if a dose of STALIX D 100+10 is missed?

If you miss a dose of STALIX D 100+10, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should STALIX D 100+10 be stored?

Store STALIX D 100+10 at room temperature, typically between 20°C to 25°C, and protect it from moisture. Keep the medicine in its original packaging and ensure it is stored out of the sight and reach of children. Do not use the medicine after its expiry date.