Mirbeg 25 Mg Tablet (10 Tab)

MIRBEG 25 MG TABLET

MIRBEG 25 MG TABLET is a medication manufactured by IPCA LABORATORIES LTD., primarily used for the management of overactive bladder (OAB) symptoms.

Name

• Brand Name: MIRBEG 25 MG TABLET
• Common Name (Active Ingredient): Mirabegron

Composition Each tablet contains Mirabegron 25 mg as the active ingredient. It is an extended-release formulation.

Uses MIRBEG 25 MG TABLET is prescribed for the treatment of overactive bladder (OAB) in adults. This condition is characterized by symptoms such as:

• Frequent feeling of a need to urinate (increased urinary frequency)
• Sudden, uncontrollable urge to urinate (urgency)
• Inability to control urination, leading to leakage (urgency incontinence) Mirabegron works by relaxing the bladder muscles, which increases the bladder's capacity to hold more urine, thereby reducing these symptoms.

Dosage and Administration The typical dosage is 25 mg, taken once daily. The tablet should be swallowed whole with a glass of water, with or without food. It should not be crushed, chewed, or broken. Do not stop taking the medicine before the completion of the prescribed duration, as it may lead to a worsening of symptoms.

Side Effects Common side effects of MIRBEG 25 MG TABLET include:

• High blood pressure (hypertension)
• Headache
• Nasopharyngitis (inflammation of the nose and throat)
• Urinary tract infection (UTI)
• Constipation
• Dizziness
• Tachycardia (fast heartbeat)
• Nausea or vomiting
• Stomach pain

Serious side effects, though rare, can include angioedema (rapid swelling beneath the skin) and urinary retention, particularly in patients with bladder outlet obstruction.

Precautions

• Allergy: Do not take MIRBEG 25 MG TABLET if you are allergic to mirabegron or any of its ingredients.
• Blood Pressure: Use with caution if you have high blood pressure, especially uncontrolled hypertension, as it may further increase blood pressure. Regular monitoring of blood pressure is recommended.
• Urinary Retention: Administer with caution in patients with bladder outlet obstruction (BOO) due to an increased risk of urinary retention.
• Kidney and Liver Conditions: Use with caution in patients with kidney or liver problems, as dose adjustments may be necessary.
• Heart Conditions: Patients with heart-related problems should use this medicine with caution, and blood pressure and heart rate should be monitored.
• Pregnancy and Breastfeeding: It is not recommended during pregnancy due to limited safety information and should only be used if the potential benefit outweighs the potential risk. Women who may become pregnant are advised to use proper birth control measures. It is probably unsafe to use while breastfeeding as components may pass into milk.
• Children: MIRBEG 25 MG TABLET is not recommended for use in children under 18 years of age due to a lack of safety and efficacy data.
• Alcohol: Avoid consuming alcohol while on treatment, as it may cause undesirable effects.
• Interactions: Inform your doctor about all ongoing medications, including herbal supplements, as mirabegron can interact with certain medicines like anti-infectives, heart medicines (e.g., digoxin), some antidepressants (e.g., imipramine, desipramine), and anti-allergic medicines.

Storage Store MIRBEG 25 MG TABLET at room temperature, protected from moisture and heat. Keep it out of reach and sight of children and pets.

Here are frequently asked questions about MIRBEG 25 MG TABLET (Mirabegron):

What is MIRBEG 25 MG TABLET used for?

MIRBEG 25 MG TABLET, containing Mirabegron, is primarily used to treat the symptoms of an overactive bladder (OAB) in adults. These symptoms include a sudden, uncontrollable urge to urinate (urgency), frequent urination throughout the day and night (urinary frequency), and the unintentional loss of urine (urgency incontinence). It is also used to treat neurogenic detrusor overactivity (NDO), an overactive bladder caused by a nerve problem, in children aged 3 years and older.

How does MIRBEG 25 MG TABLET work?

MIRBEG 25 MG TABLET works by relaxing the muscle around your bladder, known as the detrusor muscle, during the storage phase of the urinary cycle. It achieves this by stimulating specific receptors in the bladder called beta-3 adrenergic receptors. This relaxation increases the bladder's capacity to hold more urine, thereby reducing feelings of urgency and the need to urinate frequently.

What is the usual dosage for MIRBEG 25 MG TABLET?

For adults with overactive bladder, the usual starting dosage is 25 mg taken once a day. Your doctor may increase the dose to a maximum of 50 mg once daily after 4 to 8 weeks if your symptoms do not improve. The tablet should be swallowed whole with water and can be taken with or without food. If you have kidney or liver problems, your doctor may prescribe a lower dose.

What are the possible side effects of MIRBEG 25 MG TABLET?

Common side effects can include increased blood pressure (hypertension), urinary tract infections (UTIs), headache, nasopharyngitis (common cold symptoms), constipation, diarrhea, dizziness, and a faster heart rate (tachycardia). More serious, but rare, side effects can include angioedema (swelling of the face, lips, tongue, or throat, which can be life-threatening) and urinary retention (difficulty emptying the bladder). You should contact your doctor immediately if you experience severe side effects or any signs of an allergic reaction.

Is MIRBEG 25 MG TABLET safe during pregnancy or breastfeeding?

MIRBEG 25 MG TABLET is generally not recommended during pregnancy as there is not enough information to confirm its safety, and potential risks to the fetus cannot be ruled out. If you are pregnant or planning to become pregnant, discuss this with your doctor. It is not known if Mirabegron passes into breast milk or if it can affect a breastfed child. Therefore, it is important to consult your doctor if you are breastfeeding or plan to breastfeed to weigh the potential benefits against any potential risks.

Can MIRBEG 25 MG TABLET be taken with other medications?

MIRBEG 25 MG TABLET can interact with certain other medications. It can increase the levels of drugs metabolized by CYP2D6, such as metoprolol, desipramine, thioridazine, flecainide, and propafenone, potentially increasing their side effects. Caution is also advised when taking it with other medications for overactive bladder (antimuscarinics) or other anticholinergic drugs, as this may increase the risk of urinary retention. Always inform your doctor about all medications, supplements, and herbal products you are taking.

What precautions should be taken while taking MIRBEG 25 MG TABLET?

It is important for your doctor to regularly monitor your blood pressure, especially if you have a history of high blood pressure, as this medicine can increase blood pressure. MIRBEG 25 MG TABLET is not recommended for individuals with severe uncontrolled high blood pressure or severe liver or kidney disease. Use with caution if you have a bladder outlet obstruction (difficulty emptying your bladder) as it may increase the risk of urinary retention. Inform your doctor about any allergies you have had to medicines.

What happens if a dose of MIRBEG 25 MG TABLET is missed?

If you miss a dose of MIRBEG 25 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose (typically within 6 to 12 hours), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should MIRBEG 25 MG TABLET be stored?

Store MIRBEG 25 MG TABLET in its original closed container at room temperature, away from excessive heat, moisture, and direct light. Keep this medicine out of reach of children and pets.