Vylda Dm 100/10/500

VYLDA DM 100/10/500

VYLDA DM 100/10/500 is a combination medication meticulously formulated by EMCURE PHARMACEUTICALS LTD for the management of type 2 diabetes mellitus. This oral antidiabetic agent provides a multi-pronged approach to glycemic control by addressing various pathways involved in glucose regulation.

Composition Each tablet of VYLDA DM 100/10/500 contains three active pharmaceutical ingredients:

• Dapagliflozin: 10 mg
• Metformin: 500 mg
• Vildagliptin: 100 mg

Uses VYLDA DM 100/10/500 is prescribed for the treatment of type 2 diabetes mellitus in adults, especially when diet and exercise alone are insufficient to control blood sugar levels. Its benefits extend to:

• Controlling high blood sugar levels.
• Improving insulin sensitivity and managing insulin resistance.
• Reducing glucose production in the liver.
• Increasing glucose excretion through urine.
• Potentially reducing the risk of heart disease, slowing the progression of diabetic nephropathy (kidney disease), and diabetic neuropathy (nerve damage).
• Managing insulin resistance associated with polycystic ovary syndrome (PCOS) (off-label use).

Dosage and Administration The dosage and timing of VYLDA DM should be determined by a healthcare provider based on individual needs and response to treatment. It is recommended to take VYLDA DM with food to minimize potential gastrointestinal side effects. Tablets should be swallowed whole and not crushed, broken, or chewed. Do not stop taking this medicine without consulting your doctor.

Side Effects Common side effects may include:

• Nausea, vomiting, diarrhea, abdominal pain
• Headache
• Frequent urination, urinary tract infection, vaginal yeast infection
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Dizziness

Serious but rare side effects can include:

• Allergic reactions
• Lactic acidosis (a rare but serious side effect, symptoms include tiredness, weakness, muscle pain, sleepiness, abdominal pain, and breathing problems)
• Liver problems
• Acute pancreatitis.

Precautions

• Allergies and Medical History: Inform your doctor about any allergies to the ingredients or any pre-existing medical conditions, especially kidney or liver problems, heart problems (including recent heart attack), or severe infections.
• Alcohol Consumption: Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia (low blood sugar) and lactic acidosis.
• Pregnancy and Breastfeeding: VYLDA DM is generally not recommended during pregnancy or breastfeeding. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking to prevent potential drug interactions. Caution is advised with diuretics, insulin, insulin secretagogues (like sulfonylureas), and ACE inhibitors, as they may increase the risk of hypoglycemia or other adverse effects.
• Kidney and Liver Impairment: Use with caution in patients with renal impairment, as it increases the risk of lactic acidosis. Not recommended for patients with liver disease.
• Children: Not recommended for use in children below 18 years of age.
• Driving: It is not known whether VYLDA DM alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react, such as dizziness.
• Vitamin B12: Long-term metformin therapy may reduce vitamin B12 absorption, and annual screening is recommended.
• Lifestyle Modifications: This medication works best when combined with a healthy lifestyle, including a balanced diet, regular exercise, and weight management.

Storage Store VYLDA DM 100/10/500 at room temperature, below 30°C. Keep it in a cool, dry place away from direct sunlight, heat, and moisture. Keep out of reach of children and pets.

Here are frequently asked questions about VYLDA DM 100/10/500 by EMCURE PHARMACEUTICALS LTD:

What is Vylda DM 100/10/500 used for?

VYLDA DM 100/10/500 is an anti-diabetic combination medication used to manage type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone are not sufficient to control blood sugar levels. This medicine helps improve glycemic control and can reduce the risk of serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and cardiovascular disease.

How does Vylda DM 100/10/500 work?

VYLDA DM 100/10/500 contains three active ingredients: Dapagliflozin, Vildagliptin, and Metformin, which work through different mechanisms to lower blood sugar levels.

• Dapagliflozin (10mg) is a sodium-glucose cotransporter-2 (SGLT2) inhibitor that helps remove excess glucose from the body by increasing its excretion through urine.
• Vildagliptin (100mg) is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases the levels of natural hormones called incretins, which stimulate the pancreas to release more insulin after meals and reduce the amount of sugar produced by the liver when blood sugar is high.
• Metformin (500mg) belongs to the biguanide class. It works by decreasing the amount of glucose produced by the liver, reducing glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

What is the usual dosage of Vylda DM 100/10/500?

VYLDA DM 100/10/500 should be taken exactly as prescribed by your doctor. It is generally recommended to take it with or after meals, with a glass of water, to help reduce potential stomach upset. The tablet should be swallowed whole and not crushed or chewed. Do not alter your dosage or stop the medication without consulting your doctor.

What are the possible side effects of Vylda DM 100/10/500?

Common side effects can include low blood sugar (hypoglycemia), genital infections, urinary tract infections, increased urination, painful urination, back pain, dizziness, nausea, vomiting, diarrhea, headache, and fatigue. More serious but less common side effects can include vitamin B12 deficiency, abnormal liver function, and lactic acidosis. If any side effects worsen or persist, or if you experience symptoms like fever, chills, severe pain during urination, swelling of the face/tongue/throat, or difficulty breathing, contact your doctor immediately.

Is Vylda DM 100/10/500 safe during pregnancy or breastfeeding?

VYLDA DM 100/10/500 is generally not recommended for use during pregnancy or breastfeeding due to limited information on its safety. Dapagliflozin and Vildagliptin lack sufficient safety data in pregnant women, and VYLDA DM is known to pass into breast milk. If you are pregnant, planning to conceive, or breastfeeding, inform your doctor before taking this medicine.

Can Vylda DM 100/10/500 be taken with other medications?

Inform your doctor about all current medications, supplements, or herbal products you are taking to avoid potential interactions. VYLDA DM 100/10/500 may interact with other diabetic medications (like insulin or sulfonylureas, requiring dosage adjustment), diuretics (water pills), asthma medications (like salbutamol or terbutaline), birth control pills, thyroid medicines, corticosteroids, and certain heart medications. Alcohol consumption should be limited or avoided as it can increase the risk of low blood sugar and lactic acidosis.

What precautions should be taken while taking Vylda DM 100/10/500?

It is important to follow a healthy diet and engage in regular exercise as advised by your doctor while taking this medication. Avoid excessive alcohol intake. Inform your doctor if you have liver or severe kidney problems, heart problems, or a history of lactic acidosis, as these conditions may affect the suitability or dosage of the medicine. Regular monitoring of blood sugar levels is essential. If you experience symptoms of low blood sugar while driving, consume a sugary snack or juice.

What happens if a dose of Vylda DM 100/10/500 is missed?

If you miss a dose of VYLDA DM 100/10/500, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Vylda DM 100/10/500 be stored?

Store VYLDA DM 100/10/500 in a cool, dry place, protected from direct sunlight and moisture. Keep it out of sight and reach of children and pets. Do not use the medicine past its expiry date.