Twincal 10 Mg Tablet (10 Tab)

TWINCAL 10 MG TABLET

TWINCAL 10 MG TABLET is a medication manufactured by ZYDUS HEALTHCARE LIMITED, primarily used in the management of high blood pressure.

• Name

  • Brand Name: Twincal 10 Tablet
  • Common Name: Cilnidipine

• Composition Each tablet contains Cilnidipine 10 mg as the active ingredient.

• Uses TWINCAL 10 MG TABLET is a calcium channel blocker that works by relaxing and widening blood vessels, allowing blood to flow more easily and reducing the workload on the heart. It is prescribed for:

  • Treatment of Hypertension (high blood pressure)
  • Prevention of Heart Attack
  • Prevention of Stroke
  • Prevention of Angina (heart-related chest pain)

• Dosage and Administration

  • The typical adult dosage is 5-10 mg once daily, which may be increased to 20 mg once daily if necessary, as advised by a doctor.
  • It can be taken with or without food, but it is best to take it at the same time each day to maintain consistent levels in the body.
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
  • This is a long-term treatment, and patients should not stop taking the medicine abruptly without consulting their doctor, even if they feel well.

• Side Effects

  • Common Side Effects: Headache, dizziness, fatigue, sleepiness, flushing (sense of warmth), palpitations (unusual heartbeat), edema (swelling, especially in the feet and ankles), nausea, abdominal pain, rash, muscle pain, eye pain, tremors, decreased blood pressure, increased urination, lethargy, and gingival hyperplasia (enlargement of gums).
  • Consult your doctor if any of these side effects bother you or do not go away.

• Precautions

  • Contraindications: TWINCAL 10 MG TABLET is not recommended for individuals with severe aortic stenosis, cardiogenic shock, severe low blood pressure (hypotension), or known allergy to Cilnidipine or any other ingredients.
  • Special Warnings:
    • Pregnancy and Breastfeeding: Information on its use during pregnancy and breastfeeding is not fully available; consult a doctor.
    • Liver and Kidney Conditions: Use with caution in patients with liver or kidney problems.
    • Heart Problems: Use with caution in patients with other severe heart problems such as heart failure or narrowing of heart valves.
    • Driving and Operating Machinery: May cause dizziness or sleepiness; exercise caution when driving or operating machinery.
    • Alcohol: Caution is advised when consuming alcohol.
    • Grapefruit Juice: Avoid consuming grapefruit juice as it can cause serious side effects.
    • Pediatric Use: Not recommended for use in children under 18 years unless prescribed by a doctor.
  • Drug Interactions: Inform your doctor about all other medicines, herbal preparations, and supplements you are taking, especially other blood pressure medications, medicines for brain disorders, or those for uneven heart rhythm, to avoid potential interactions.

• Storage Store below 30°C, in a cool and dry place, away from direct sunlight. Keep out of the sight and reach of children.

What is TWINCAL 10 MG TABLET used for?

TWINCAL 10 MG TABLET is primarily used to manage high blood pressure (hypertension) and its associated vascular disorders. It can also be prescribed to help prevent conditions such as angina (chest pain related to the heart), heart attack, and stroke, as well as for end-organ protection in hypertension.

How does TWINCAL 10 MG TABLET work?

This medicine contains Cilnidipine, which is a calcium channel blocker. It works by inhibiting the entry of calcium ions into the smooth muscle cells of your blood vessels. This action causes the blood vessels to relax and widen, allowing blood to flow more easily with less pressure. This reduces the strain on the heart and helps lower blood pressure.

What is the usual dosage of TWINCAL 10 MG TABLET?

The usual dosage for adults is typically 5 mg to 10 mg taken once daily, as prescribed by your doctor. In some severe cases, the dosage may be increased up to 20 mg once daily. It can be taken with or without food, but it is best to take it at the same time each day to maintain consistent blood levels.

What are the possible side effects of TWINCAL 10 MG TABLET?

Common side effects may include swelling of the ankles or other body parts (edema), headache, dizziness, sleepiness, flushing (redness and warmth of the skin), palpitations (fast heartbeat), stomach pain, nausea, diarrhea, constipation, indigestion, skin rashes, fatigue, muscle pain, eye pain, tremors, decreased blood pressure, and gingival hyperplasia (enlargement or overgrowth of the gums). Contact your doctor if any of these side effects trouble you or persist.

Is TWINCAL 10 MG TABLET safe during pregnancy or breastfeeding?

During Pregnancy: TWINCAL 10 MG TABLET should be used in pregnant women only if it is considered necessary by the physician, as there is limited information, and it is generally not recommended for use in pregnancy as it may harm the fetus. During Breastfeeding: It should be used with caution in breastfeeding women as it may pass through breast milk to the nursing infant. It is generally not recommended while breastfeeding. Always consult your doctor for advice if you are pregnant or breastfeeding.

Can TWINCAL 10 MG TABLET be taken with other medications?

Yes, but it's crucial to inform your doctor about all other medicines, herbal preparations, and supplements you are currently taking or plan to take. TWINCAL 10 MG TABLET can interact with various medications, including certain anticancer agents, antiepileptics (e.g., carbamazepine, phenytoin), antibiotics (e.g., erythromycin), anti-TB agents (e.g., rifampicin), other antihypertensives, cardiac agents (e.g., quinidine, digoxin), and antipsychotics. You should also avoid consuming grapefruit juice while on this medication as it can increase the absorption of the medicine and potentially lead to excessive lowering of blood pressure and side effects.

What precautions should be taken while using TWINCAL 10 MG TABLET?

Before taking TWINCAL 10 MG TABLET, inform your doctor if you have any liver or kidney problems. You should also inform your doctor if you have severe low blood pressure (hypotension), edema, congestive heart failure, or other severe heart problems such as narrowing of heart valves (aortic stenosis) or a recent heart attack. The medicine is not recommended for use in patients with severe aortic stenosis or cardiogenic shock. Do not stop taking the medicine without consulting your doctor, as abrupt discontinuation can cause your blood pressure to rise again. Be cautious if driving or operating machinery, as it may cause dizziness or sleepiness. It is also advisable to limit alcohol consumption while on this medication.

What happens if a dose of TWINCAL 10 MG TABLET is missed?

If you miss a dose of TWINCAL 10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should TWINCAL 10 MG TABLET be stored?

TWINCAL 10 MG TABLET should be stored at room temperature (below 30°C) in a cool and dry place, away from direct sunlight and dampness. Keep it out of sight and reach of children.