Glytrin Tablet

Here is a detailed product description for GLYTRIN TABLET:

GLYTRIN TABLET

• Name: Glytrin Tablet (Common Name), GLYTRIN TABLET by MEDLEY PHARMACEUTICALS LTD. (Brand Name)

• Composition: The active ingredient in GLYTRIN TABLET is Teneligliptin, typically in 20 mg strength.

• Uses: GLYTRIN TABLET is an anti-diabetic medication primarily used to manage Type 2 Diabetes Mellitus in adults. It is prescribed as an adjunct to diet and exercise to control elevated blood sugar levels. It can be used alone or in combination with other anti-diabetic medicines when diet and exercise alone are insufficient to achieve adequate glycemic control. The medication helps by promoting insulin secretion from the pancreas, decreasing glucagon levels, regulating post-meal blood sugar, and improving the body's response to insulin. It also aims to prevent long-term complications associated with diabetes, such as kidney damage, nerve problems, and eye damage.

• Dosage and Administration: GLYTRIN TABLET should be taken exactly as advised by a physician. It is typically swallowed whole with a glass of water, preferably after meals, and usually once daily. Do not crush or chew the tablet. The correct dose and duration of therapy are determined by the doctor based on the patient's age, body weight, and disease condition. It is important to take the medicine regularly at the same time each day for optimal benefit and not to stop taking it without consulting a doctor.

• Side Effects:

  • Common Side Effects: Hypoglycemia (low blood sugar), headache, dizziness, constipation, diarrhea, fever, upper respiratory tract infection, and nasopharyngitis (cold-like symptoms).
  • Serious Side Effects (Rare): Inflammation of the pancreas (pancreatitis), which can be severe, and heart failure. Patients experiencing severe stomach pain should stop the medication and seek immediate medical attention.

• Precautions:

  • Contraindications: GLYTRIN TABLET is not suitable for patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, or known allergy to its components. It is generally not recommended during breastfeeding.
  • Warnings: Consult a doctor before use if pregnant or planning pregnancy. Caution is advised for patients with liver or kidney problems, heart problems, acute pancreatitis, adrenal insufficiency, malnutrition, stomach problems (such as recent surgery or intestinal obstruction), or if consuming alcohol. Alcohol consumption can increase the risk of hypoglycemia and lactic acidosis when combined with other antidiabetic agents. Patients should monitor blood sugar levels and carry sugary snacks to counteract potential hypoglycemia. Driving or operating machinery should be avoided if dizziness occurs.
  • Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products being taken. GLYTRIN TABLET may interact with other antidiabetic medicines (increasing hypoglycemia risk), beta-blockers, salicylic acid, certain antidepressants, adrenaline, thyroid hormones, medicines for irregular heartbeats, antifungal medications (like ketoconazole), and antibiotics (like rifampicin).

• Storage: Store GLYTRIN TABLET at room temperature, typically below 25°C or 30°C. Keep it in a cool, dry place, protected from moisture, direct sunlight, and heat. Ensure it is kept out of the sight and reach of children.

GLYTRIN TABLET by MEDLEY PHARMACEUTICALS LTD. is a medication primarily used for the management of Type 2 Diabetes Mellitus. Its active ingredient is Teneligliptin. Below are some frequently asked questions about this medicine.

What is GLYTRIN TABLET used for?

GLYTRIN TABLET is used as an adjunct to diet and exercise to control elevated blood sugar levels in adult patients with Type 2 Diabetes Mellitus. It helps manage blood sugar when diet and exercise alone are insufficient, and can be prescribed alone or in combination with other diabetes medications. It also aims to prevent serious long-term complications of diabetes such as kidney damage, blindness, nerve problems, and heart issues.

How does GLYTRIN TABLET work?

GLYTRIN TABLET contains Teneligliptin, which is a dipeptidyl peptidase (DPP)-4 inhibitor. It works by blocking the actions of the DPP-4 enzyme, which normally breaks down incretin hormones. By inhibiting DPP-4, Teneligliptin increases the levels of incretins, leading to enhanced insulin secretion from the pancreas in response to high blood glucose. It also helps regulate blood sugar by decreasing glucagon secretion, thereby reducing glucose production by the liver.

What is the usual dosage for GLYTRIN TABLET?

The typical adult dosage of GLYTRIN TABLET (Teneligliptin) is 20-40 mg once daily, taken orally. It should be taken as advised by your doctor, preferably after meals, and at the same time each day for best results. Your doctor will determine the correct dose and duration of therapy based on your age, body weight, and disease condition.

What are the possible side effects of GLYTRIN TABLET?

Common side effects include hypoglycemia (low blood sugar), headache, dizziness, constipation, diarrhea, nausea, nasal congestion, and increased body temperature. More serious, though rare, side effects can include inflammation of the pancreas (pancreatitis) and heart failure. If you experience severe abdominal pain, or symptoms of heart failure, contact your doctor immediately.

Is GLYTRIN TABLET safe during pregnancy or breastfeeding?

GLYTRIN TABLET should be used in pregnant women only if prescribed by a physician, after evaluating the potential risks and benefits. It is generally considered probably unsafe or contraindicated during breastfeeding, and breast-feeding should be stopped during its management. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can GLYTRIN TABLET be taken with other medications?

GLYTRIN TABLET can interact with various medications. Inform your doctor if you are taking other medicines for diabetes (like glimepiride, insulin), certain antifungals (ketoconazole, itraconazole), antibiotics (rifampicin), beta-blockers (atenolol, propranolol), salicylic acid, medicines for depression (phenelzine, selegiline), adrenaline, or thyroid hormones. Combining it with other anti-diabetic agents may increase the risk of hypoglycemia.

What precautions should be taken while using GLYTRIN TABLET?

GLYTRIN TABLET is not suitable for patients with Type 1 Diabetes Mellitus or diabetic ketoacidosis. Use with caution if you have liver or heart problems, a history of pancreatitis, or are malnourished. Avoid excessive alcohol consumption, as it can increase the risk of low blood sugar and other side effects. Monitor your blood sugar levels regularly and carry a sugary snack to counteract mild hypoglycemia symptoms. Do not drive or operate machinery if you experience dizziness.

What happens if a dose is missed?

If you miss a dose of GLYTRIN TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects, including low blood sugar. If you miss multiple doses or experience symptoms of high blood sugar, contact your doctor.

How should GLYTRIN TABLET be stored?

GLYTRIN TABLET should be stored in a cool, dry place, typically at room temperature (between 20°C to 25°C or below 30°C). Protect it from direct sunlight, moisture, and excessive heat or cold. Keep the medication out of the reach of children.