Lupirtin 100 Capsule

LUPIRTIN 100 CAPSULE

Name

Brand Name: Lupirtin 100 Capsule Common Name: Flupirtine

Composition

Lupirtin 100 Capsule contains Flupirtine 100 mg as its active ingredient. It is categorized as a non-opioid analgesic and muscle relaxant.

Uses

Lupirtin 100 Capsule is a pain-relieving medicine used to treat acute and chronic pain. It is prescribed for various conditions, including:

• Pain after surgery or operation
• Severe headache
• Tumor pain
• Pain during menstruation (menstrual cramps)
• Muscle pain and musculoskeletal pain
• Nerve pain
• Back pain and osteoarthritis It works by blocking the transmission of pain signals to the brain and by relaxing muscles.

Dosage and Administration

Lupirtin 100 Capsule should be taken as directed by your doctor.

• Swallow the capsule whole with a glass of water; do not cut, break, or chew it.
• It can be taken with or without food, but it is better to take it at a fixed time daily to maintain a constant level of medicine in the body.
• The usual adult dosage is one 100 mg capsule 3 to 4 times daily, with a maximum of 6 doses daily.
• The duration of treatment should not exceed 8 days without a medical review, or 4 weeks on repeated prescription.
• Do not skip a dose or discontinue the treatment without consulting your doctor.

Side Effects

Common side effects associated with Lupirtin 100 Capsule include:

• Fatigue
• Dizziness
• Nausea and vomiting
• Stomach pain/discomfort, gas, constipation, diarrhea
• Heartburn
• Dry mouth
• Increased sweating
• Loss of appetite
• Sleeping problems/sleep disturbance
• Shakiness
• Drowsiness
• Pruritus (itchy skin)
• Gastric fullness
• Muscle tremor Most side effects are temporary and resolve over time, but consult your doctor if they persist or worsen.

Precautions

• Pregnancy: Not recommended during pregnancy as there is limited safety data. Consult your doctor if you are pregnant, think you may be pregnant, or are planning a pregnancy.
• Breastfeeding: Flupirtine passes into breast milk, so it is not recommended during breastfeeding.
• Liver Problems: Contraindicated in patients with liver problems. Use with extreme caution as there is an increased risk of liver damage. Regular monitoring of liver function tests is recommended, especially with prolonged administration or in elderly patients. Immediately contact your doctor if you experience symptoms like nausea, vomiting, stomach discomfort, loss of appetite, fatigue, dark urine, or jaundice.
• Kidney Problems: Use with caution if you have kidney problems. Your doctor may suggest monitoring kidney function.
• Alcohol Consumption: Avoid or limit alcohol consumption during treatment as it may increase the risk of liver problems, drowsiness, and dizziness.
• Driving and Operating Machinery: Lupirtin 100 Capsule may cause dizziness and sleepiness; therefore, avoid driving or operating machines if you feel unwell or are unable to be alert.
• Age Restrictions: Not recommended for use in children and adolescents below 18 years of age due to a lack of safety and efficacy data. Use with caution in elderly patients (above 65 or 70 years of age) due to potential liver and kidney issues.
• Other Conditions: Inform your doctor if you are allergic to Flupirtine or any other ingredients, have a brain disorder, suffer from any condition causing muscle weakness (e.g., myasthenia gravis), or are taking blood thinners (like warfarin, heparin) or any other medicines that may cause liver injury. This medicine may interfere with lab tests.

Storage

Store Lupirtin 100 Capsule below 30°C. Keep it in a cool and dry place, protected from light and moisture, and out of the sight and reach of children.

What is LUPIRTIN 100 CAPSULE used for?

LUPIRTIN 100 CAPSULE is a pain-relieving medicine used to treat various types of acute and chronic pain. This includes pain after surgery, severe headaches, tumor pain, musculoskeletal pain, nerve pain, painful menstruation (menstrual cramps), and pain associated with muscle spasms. It is not recommended for use in children and adolescents under 18 years of age.

How does LUPIRTIN 100 CAPSULE work?

LUPIRTIN 100 CAPSULE contains Flupirtine as its active ingredient. Flupirtine works as a non-opioid analgesic and muscle relaxant. It functions by blocking the release of certain chemical substances responsible for pain sensation and by modulating the activity of potassium channels in the central nervous system, which reduces nerve cell excitability. It also acts as an NMDA glutamate receptor antagonist, further contributing to its pain-relieving effects and helping to relax muscles.

What is the usual dosage for LUPIRTIN 100 CAPSULE?

The typical adult dosage is one 100 mg capsule, taken 3 to 4 times daily, with a maximum of 6 doses daily. For more severe pain, single 200 mg oral doses may be taken up to 3 times daily. The duration of treatment should not exceed 8 days without a medical review, or 4 weeks on repeated prescription. It can be taken with or without food, but it is generally recommended to take it at a fixed time each day as directed by your doctor. Swallow the capsule whole with a glass of water; do not cut, break, or chew it.

What are the possible side effects of LUPIRTIN 100 CAPSULE?

Common side effects of LUPIRTIN 100 CAPSULE include fatigue, dizziness, drowsiness, nausea, vomiting, stomach pain, diarrhea, constipation, heartburn, dry mouth, increased sweating, loss of appetite, and sleeping problems. Most of these side effects are temporary and usually resolve as your body adjusts to the medicine. If any side effects persist or worsen, you should consult your doctor.

Is LUPIRTIN 100 CAPSULE safe during pregnancy or breastfeeding?

LUPIRTIN 100 CAPSULE is generally not recommended for use during pregnancy due to limited safety data available in pregnant women. If you are pregnant, think you may be pregnant, or are planning a pregnancy, consult your doctor to discuss the potential benefits and risks. Flupirtine, the active ingredient, passes into breast milk, so it is also not recommended during breastfeeding. Your doctor may prescribe it only if the potential benefits outweigh the risks.

Can LUPIRTIN 100 CAPSULE be taken with other medications?

LUPIRTIN 100 CAPSULE can interact with certain medications. It is important to inform your doctor about all medicines, supplements, or herbal products you are currently taking or might take. Particular caution is advised with:

• CNS depressants (e.g., diazepam, barbiturates) as it may increase sedation and breathing problems.
• Muscle relaxants (e.g., baclofen, tizanidine) as their effects may be enhanced.
• Anticoagulants (e.g., warfarin) as it may increase the effect of blood thinners, requiring close monitoring of blood coagulation parameters.
• Medicines that may cause liver injury or those that affect liver function, as Flupirtine is metabolized in the liver.

What precautions should be taken with LUPIRTIN 100 CAPSULE?

Several precautions should be taken while using LUPIRTIN 100 CAPSULE:

• Liver Function: This medicine is not recommended if you have pre-existing liver problems. Your doctor will likely conduct liver function tests before and during treatment, especially weekly during prolonged use. Immediately contact your doctor if you experience symptoms like nausea, vomiting, stomach pain, dark urine, or jaundice.
• Kidney Function: Use with caution if you have kidney problems, as dose adjustments or monitoring may be necessary.
• Alcohol: Avoid or limit alcohol consumption as it can increase the risk of liver damage and worsen side effects like dizziness and drowsiness.
• Driving and Machinery: LUPIRTIN 100 CAPSULE may cause dizziness and drowsiness, so avoid driving or operating heavy machinery if you experience these symptoms.
• Age Restrictions: It is not recommended for individuals under 18 years of age. Use with caution in elderly patients.
• Myasthenia Gravis: Avoid use if you suffer from conditions causing muscle weakness, such as myasthenia gravis, as it may worsen the condition.

What happens if a dose of LUPIRTIN 100 CAPSULE is missed?

If you miss a dose of LUPIRTIN 100 CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should LUPIRTIN 100 CAPSULE be stored?

LUPIRTIN 100 CAPSULE should be stored in a cool and dry place. Protect it from light and moisture, and keep it out of the sight and reach of children.