Synaptol Sr 450

SYNAPTOL SR 450

Name:

• Brand Name: SYNAPTOL SR 450
• Common Name: Synaptol SR 450 Tablet
• Manufacturer: Sun Pharmaceutical Industries Ltd.

Composition:

• Active Ingredient: Tolperisone 450mg

Uses: SYNAPTOL SR 450 is a centrally acting muscle relaxant used to alleviate various conditions involving muscle stiffness and pain.

• Musculoskeletal Pain: Primarily treats acute musculoskeletal pain, which includes pain originating from muscles, bones, or joints. It helps in relieving rigidity, tension, stiffness, and muscle spasms.
• Back Pain: Effective in providing relief for severe back pain.
• Neurological Conditions: Offers symptomatic relief for muscle spasms associated with neurological disorders, such as those caused by stroke, spinal cord injury, multiple sclerosis, Parkinson's disease, cerebral palsy, and traumatic brain injury.
• Mechanism: It works by acting on the spinal cord and brain centers to relieve muscle contraction or stiffness without reducing muscle strength. It also increases blood supply to the muscles, which improves movement and reduces pain.

Dosage and Administration:

• Take SYNAPTOL SR 450 as prescribed by your doctor.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• It is generally recommended to take this medicine with food or milk to prevent stomach upset and reduce the chance of side effects.
• Do not exceed the prescribed dose.

Side Effects: Common side effects may include:

• Dizziness, sleepiness, or drowsiness
• Diarrhoea, abdominal pain, nausea, vomiting, dryness of mouth, stomach upset, gastritis
• Sweating, weakness, fatigue, muscle weakness
• Headache
• Rash or redness on skin, itching Less common but potentially serious side effects, such as allergic reactions (flushing, severe itching, wheezing, difficulty breathing, swelling of face/lips/tongue/throat, low blood pressure, fast heartbeat), require immediate medical attention.

Precautions:

• Allergies: Inform your doctor if you have any allergies, especially to Tolperisone or other components of the medicine.
• Pregnancy & Breastfeeding: Use with caution during pregnancy, only if clearly necessary and advised by a doctor. It is not recommended for use in breastfeeding women.
• Liver & Kidney Impairment: Not recommended for patients with severe liver or kidney impairment. Use with caution in patients with existing liver or kidney problems, as monitoring may be required.
• Alcohol: Avoid or limit alcohol consumption while taking SYNAPTOL SR 450, as it may increase drowsiness and dizziness.
• Driving & Operating Machinery: This medicine may cause dizziness or sleepiness. Avoid driving or operating machinery until you know how it affects you.
• Other Conditions: Inform your doctor if you have myasthenia gravis, asthma, or hay fever.
• Children: Use with caution in children (from 3 months to 14 years of age) with close monitoring. Some sources suggest not for use below 18 years.
• Discontinuation: Do not stop taking the medicine suddenly without consulting your doctor, even if your symptoms improve.

Storage:

• Store in a cool and dry place, away from direct sunlight.
• Keep out of sight and reach of children and pets.
• Maintain storage temperature between 10ºC to 25ºC or below 30ºC.

What is Synaptol SR 450 used for?

Synaptol SR 450 is primarily used to treat acute musculoskeletal pain, muscle spasms, rigidity, tension, and stiffness. It helps alleviate pain and improve movement in muscles, bones, or joints. It can also provide relief from spasticity, which is muscle stiffness that may occur due to various conditions affecting the nervous system.

How does Synaptol SR 450 work?

Synaptol SR 450 contains the active ingredient Tolperisone, which is a centrally acting muscle relaxant. It works by acting on the spinal cord and centers in the brain to relieve muscle contraction or stiffness without reducing muscle strength. Additionally, it increases the blood supply to the muscles, which helps improve muscle movement and pain.

What is the usual dosage and how should I take it?

Synaptol SR 450 should be taken exactly as prescribed by your doctor. It is typically taken once daily. The tablet should be swallowed whole with a glass of water; do not crush, chew, or break it, as this may affect the extended-release mechanism. It is recommended to take it with or after food, or with a glass of milk, to minimize stomach upset and reduce the chance of side effects.

What are the possible side effects of Synaptol SR 450?

Common side effects may include dizziness, sleepiness or drowsiness, diarrhea, sweating, abdominal pain, weakness, fatigue, dry mouth, nausea, vomiting, muscle weakness, and headache. Most of these effects are usually temporary and may diminish as your body adjusts to the medication. If any side effects persist or worsen, you should consult your doctor.

Is Synaptol SR 450 safe during pregnancy or breastfeeding?

Synaptol SR 450 should be used with caution during pregnancy and only if clearly considered necessary by your doctor, particularly during the initial three months. It is generally not recommended for use during breastfeeding, as it may cause harm to the newborn. Always consult your doctor for advice if you are pregnant, planning to conceive, or breastfeeding.

Can Synaptol SR 450 be taken with other medications or alcohol?

Inform your doctor about all other medications you are taking to ensure there are no harmful interactions. Synaptol SR 450 may interact with anticholinergics (e.g., hyoscine, atropine), benzodiazepines (e.g., alprazolam, diazepam), pain and inflammation medicines (e.g., ibuprofen, diclofenac), certain antipsychotics (e.g., thioridazine), some antidepressants (e.g., desipramine, venlafaxine), and dextromethorphan. It is advised to avoid consuming alcohol while taking Synaptol SR 450, as it may increase drowsiness and dizziness.

What precautions should I take while using Synaptol SR 450?

Before taking Synaptol SR 450, inform your doctor if you have any allergies, myasthenia gravis (muscle weakness), asthma, or hay fever. This medicine should be used with caution if you have severe liver or kidney problems. Since it can cause dizziness or sleepiness, avoid driving or operating heavy machinery until you know how the medication affects you. Do not stop taking the medicine suddenly without consulting your doctor, even if your symptoms improve.

What should I do if I miss a dose of Synaptol SR 450?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Synaptol SR 450 be stored?

Store Synaptol SR 450 in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children and pets. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC.