Cizaspa X Tablet (15 Tab)

CIZASPA X TABLET (15 TAB) by LUPIN LTD

CIZASPA X Tablet is a combination medication designed to manage gastrointestinal disorders, particularly Irritable Bowel Syndrome (IBS), and its associated stress and anxiety.

• Name: CIZASPA X Tablet

• Composition: Each tablet contains Mebeverine (135 mg) and Chlordiazepoxide (5 mg). Mebeverine is an antispasmodic that relaxes the smooth muscles of the gastrointestinal tract, while Chlordiazepoxide is a benzodiazepine that provides anxiolytic (anti-anxiety) effects by increasing GABA activity in the brain.

• Uses: CIZASPA X Tablet is primarily used for:

  • Management of Irritable Bowel Syndrome (IBS), relieving symptoms like abdominal pain, cramping, bloating, indigestion, and irregular bowel movements.
  • Addressing other digestive problems caused by excessive stress, such as peptic ulcer, Crohn's disease, and colitis.
  • Reducing excessive tension and anxiety associated with IBS and functional bowel disorders.

• Dosage and Administration: CIZASPA X Tablet should be taken orally as advised by your physician. It is generally recommended to be taken preferably before or with meals, or on an empty stomach, usually 20 minutes before a meal. Swallow the tablet whole with a glass of water; do not crush, break, or chew it. Your doctor will determine the correct dose and duration of treatment based on your condition. Do not stop the medication abruptly due to potential withdrawal symptoms.

• Side Effects: Common side effects include:

  • Drowsiness, sleepiness, dizziness, light-headedness.
  • Tiredness, weakness, fatigue.
  • Headache.
  • Loss of balance, poor muscle control, uncoordinated body movements, slurred speech.
  • Confusion.
  • Problems in passing urine, reduced sex drive, irregular periods.
  • Constipation. Serious but rare side effects can include severe allergic reactions, suicidal thoughts, behavioral changes, or yellowing of the skin or eyes.

• Precautions:

  • Pregnancy and Breastfeeding: CIZASPA X Tablet is generally considered unsafe during pregnancy and breastfeeding. Consult your doctor.
  • Alcohol: Avoid alcohol consumption as it can increase sedative effects and may aggravate your condition.
  • Driving and Machinery: This medicine can cause drowsiness and poor muscle control, so avoid driving or operating heavy machinery until you know how it affects you.
  • Drug Interactions: Inform your doctor about all other medications, especially opioids, other CNS depressants, psychiatric medications, and pain relievers, to avoid severe interactions.
  • Medical Conditions: Inform your doctor if you have lung, liver, kidney problems, breathing problems, muscle problems, mental illnesses, glaucoma, enlarged prostate, or a history of drug abuse or chronic alcoholism.
  • Children and Elderly: Not recommended for children below 18 years. Use with caution in elderly patients due to increased sensitivity to sedative effects.

• Storage: Store CIZASPA X Tablet in a cool, dry place away from direct sunlight and moisture. Keep it in its original container, tightly closed, and out of reach of children.

What is CIZASPA X TABLET used for?

CIZASPA X TABLET is primarily used to treat Irritable Bowel Syndrome (IBS) and other digestive problems exacerbated by stress, such as peptic ulcer, Crohn's disease, and colitis. It helps manage symptoms like painful stomach cramps, abdominal pain, bloating, indigestion, irregular bowel movements, and anxiety associated with these conditions.

How does CIZASPA X TABLET work?

This medicine is a combination of two active ingredients: Mebeverine and Chlordiazepoxide. Mebeverine is an antispasmodic that works by relaxing the intestinal muscle walls, thereby relieving painful muscle spasms and cramps in the gastrointestinal tract. Chlordiazepoxide is a benzodiazepine that acts on the brain by increasing the activity of GABA, a nerve-calming chemical messenger. This action decreases abnormal nerve cell activity, reducing anxiety and tension that often worsen digestive discomfort.

What is the usual dosage for CIZASPA X TABLET?

The usual dosage for CIZASPA X TABLET is typically 1-2 tablets per day, or as advised by your doctor. It is generally recommended to take the tablet on an empty stomach, preferably 20 minutes before a meal, or with meals as directed by your physician. The tablet should be swallowed whole with water and not crushed, broken, or chewed.

What are the possible side effects of CIZASPA X TABLET?

Common side effects can include drowsiness, dizziness, fatigue, sleepiness, confusion, uncoordinated body movements, slurred speech, headache, weakness, loss of balance, problems in passing urine, reduced sex drive, and irregular periods. If any of these side effects persist or worsen, it's important to consult your doctor. Rarely, severe side effects such as allergic reactions, suicidal thoughts, worsening depression, behavioral changes, yellowing of the skin or eyes, or low blood counts may occur.

Is CIZASPA X TABLET safe during pregnancy or breastfeeding?

CIZASPA X TABLET is not recommended during pregnancy as there is evidence of risk to the developing baby, and it may cause congenital disabilities. It is also not recommended for breastfeeding mothers as it may be excreted in breast milk. Always consult your doctor for advice if you are pregnant, planning pregnancy, or breastfeeding.

Can CIZASPA X TABLET be taken with other medications?

Caution is advised when taking CIZASPA X TABLET with other medications. It should not be taken with alcohol or opioid-like substances due to the increased risk of excessive sedation and respiratory depression, which can be life-threatening. Avoid taking it with other CNS depressants, benzodiazepines, or tranquillizers. Inform your doctor about all other medicines you are taking, including those for psychiatric disorders (e.g., pimozide, haloperidol) or depression (e.g., MAO inhibitors), as interactions can occur.

What precautions should be taken while using CIZASPA X TABLET?

You should avoid consuming alcohol while taking CIZASPA X TABLET as it can worsen drowsiness and other side effects. This medicine can cause dizziness and sleepiness, so do not drive or operate heavy machinery until you know how it affects you. It is not recommended for children below 18 years of age. Use with caution in elderly patients as they may be more sensitive to sedative effects. Inform your doctor if you have liver, kidney, or lung problems, breathing issues, muscle weakness (myasthenia gravis), mental illnesses, a history of drug abuse, chronic alcoholism, an enlarged prostate gland, glaucoma, or difficulty passing urine. Do not stop taking the medicine suddenly, as it may cause withdrawal symptoms.

What happens if a dose of CIZASPA X TABLET is missed?

If you miss a dose of CIZASPA X TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should CIZASPA X TABLET be stored?

Cizaspa X Tablet should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom or near heat sources, and do not use the medicine after its expiration date. Dispose of unused medicine safely according to instructions on the pack or label.