Sitaday Dm Tab

SITADAY DM Tablet by Mankind Pharma Ltd.

Name:

• Brand Name: SITADAY DM Tablet
• Common Name: Dapagliflozin, Metformin, and Sitagliptin Tablets

Composition: SITADAY DM Tablet is a fixed-dose combination medication. Each tablet typically contains:

• Dapagliflozin 10 mg
• Metformin 500 mg
• Sitagliptin 100 mg

Uses: SITADAY DM Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults, used as an adjunct to diet and exercise to improve blood sugar control. It is particularly beneficial when single or dual therapy is insufficient. Its uses include:

• Improving blood sugar control and lowering HbA1c levels.
• Reducing insulin resistance and enhancing insulin response.
• Promoting glucose excretion from the body through urine.
• Aiding in weight and metabolic control.
• Offering cardiovascular and kidney protection by lowering the risk of heart failure and diabetic kidney disease.

Dosage and Administration: Take SITADAY DM Tablet exactly as advised by your doctor. It can be taken with or without food, but it is recommended to take it at the same time every day for optimal benefits. Swallow the tablet whole; do not crush, break, or chew it. Do not exceed the recommended dose.

Side Effects: Common side effects may include:

• Nausea, vomiting, abdominal pain, diarrhea, stomach upset.
• Headache, common cold, influenza, back pain, cough.
• Genital fungal infections, urinary tract infection, increased or more frequent urination.
• Flatulence, drowsiness, dizziness, itching, dry mouth, thirst.

Serious side effects, though rare, require immediate medical attention:

• Lactic acidosis (symptoms include weakness, breathing difficulty, severe stomach pain, unusual tiredness, muscle pain, coldness in hands/feet, dizziness).
• Ketoacidosis (nausea, vomiting, confusion, fruity breath).
• Pancreatitis (severe and persistent abdominal pain that may radiate to the back, with or without nausea and vomiting).
• Severe allergic reactions (rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing).
• Bullous pemphigoid (blistering of the skin).

Precautions:

• Allergies: Do not take if you are allergic to dapagliflozin, metformin, sitagliptin, or any other components of the tablet.
• Medical History: Inform your doctor about your complete medical history, especially if you have liver disease, severe kidney disease, respiratory failure, heart failure, a recent myocardial infarction, Type 1 diabetes mellitus, acute metabolic acidosis (lactic acidosis, diabetic ketoacidosis), dehydration, severe infection, or shock.
• Pregnancy and Breastfeeding: Sitaday DM Tablet is generally not recommended during pregnancy or breastfeeding. Consult your doctor to discuss potential risks and benefits.
• Children: This medicine is not recommended for use in children below 18 years of age.
• Alcohol: Limit or avoid excessive alcohol intake as it can increase the risk of lactic acidosis.
• Drug Interactions: Inform your doctor about all prescription, non-prescription, herbal supplements, and other medicines you are taking, especially other antidiabetic medicines, diuretics, insulin, sulfonylureas, ketoconazole, itraconazole, ritonavir, clarithromycin, and corticosteroids.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is advisable while on this medication.

Storage: Store SITADAY DM Tablet in a cool and dry place, at a consistent temperature below 30°C, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets.

What is Sitaday DM Tablet used for?

Sitaday DM Tablet is an antidiabetic medicine primarily used to manage Type 2 Diabetes Mellitus in adults. It is prescribed when blood sugar levels are not adequately controlled by metformin alone, or by dual therapy with metformin and either dapagliflozin or sitagliptin. This medicine is used as an adjunct to diet and exercise to improve blood sugar control. Additionally, it may help in weight management and reduce the risk of cardiovascular events and diabetic kidney disease.

How does Sitaday DM Tablet work?

Sitaday DM Tablet is a combination of three active ingredients: Dapagliflozin, Sitagliptin, and Metformin.

• Dapagliflozin (a sodium-glucose co-transporter 2 (SGLT2) inhibitor) works by decreasing the reabsorption of glucose in the kidneys, leading to more glucose being excreted through urine, thus lowering blood glucose levels.
• Sitagliptin (a dipeptidyl peptidase-4 (DPP-4) inhibitor) helps control blood sugar by increasing the release of insulin from the pancreas and signaling the liver to reduce glucose production when blood sugar levels are high.
• Metformin (a biguanide) decreases glucose production in the liver, reduces glucose absorption from the intestines, and enhances the body's sensitivity to insulin.

Together, these ingredients offer a multi-targeted approach to effectively control blood sugar levels.

What is the usual dosage of Sitaday DM Tablet?

The dosage of Sitaday DM Tablet is individualized by your doctor based on your health condition and response to the medicine. It is typically taken with or without food, but it is recommended to take it at the same time each day for optimal benefits. Do not alter the prescribed dose or stop taking the medicine without consulting your doctor.

What are the possible side effects of Sitaday DM Tablet?

Common side effects of Sitaday DM Tablet can include:

• Genital infections (e.g., fungal infections)
• Urinary tract infections (UTIs)
• Nasal congestion, sore throat, or common cold symptoms
• Diarrhea, nausea, vomiting, or stomach pain
• Headache
• Influenza
• Back pain
• Cough

Serious but less common side effects can include lactic acidosis (especially with liver or kidney issues, or excessive alcohol intake), pancreatitis, severe allergic reactions, and hypoglycemia (low blood sugar), particularly when taken with other antidiabetic medications. If you experience any serious or persistent side effects, consult your doctor immediately.

Is Sitaday DM Tablet safe during pregnancy or breastfeeding?

Sitaday DM Tablet is generally not recommended during pregnancy or breastfeeding due to limited information on its effects and the presence of metformin, which can pass into human milk. If you are pregnant, planning a pregnancy, or breastfeeding, it is crucial to consult your doctor before taking this medicine to discuss potential risks and benefits.

Can Sitaday DM Tablet be taken with other medications?

Sitaday DM Tablet can interact with certain medications. It is important to inform your doctor about all prescription, non-prescription, herbal supplements, and other medicines you are taking to avoid possible interactions.

• Taking it with insulin or other insulin secretagogues (like sulfonylureas) can increase the risk of hypoglycemia.
• Diuretics (e.g., furosemide, hydrochlorothiazide) may increase the risk of volume depletion and low blood pressure.
• Cationic medicines (e.g., amiloride, digoxin, trimethoprim) and carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide) may affect the action of metformin or increase the risk of lactic acidosis.
• Corticosteroids can affect blood sugar levels, impacting the effectiveness of Sitaday DM Tablet.

What precautions should be taken?

• Kidney and Liver Health: Sitaday DM Tablet should be used with caution, or avoided, in patients with severe kidney or liver impairment due to increased risk of lactic acidosis (from metformin) and other complications. Regular monitoring of kidney function is recommended.
• Alcohol Consumption: Excessive alcohol intake should be avoided as it can increase the risk of lactic acidosis, a serious side effect of metformin.
• Dehydration: Drinking plenty of fluids is important to prevent dehydration, especially due to dapagliflozin's action of increasing glucose excretion through urine.
• Allergies: Do not take Sitaday DM Tablet if you are allergic to dapagliflozin, sitagliptin, metformin, or any other ingredients in the tablet.
• Children: This medicine is not recommended for use in children below 18 years of age.
• Older Patients: Caution may be needed in elderly patients, and kidney function should be monitored.
• Surgery: Inform your doctor if you are scheduled for surgery.

What happens if a dose is missed?

If you miss a dose of Sitaday DM Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should it be stored?

Sitaday DM Tablet should be stored at a consistent temperature below 30°C. Keep the medicine away from moisture and direct sunlight, and always place it out of the reach of children. Ensure the medicine is used before its expiry date.