Gluconorm Z Xr 60 Mg Tablet (15 Tab)

GLUCONORM Z XR 60 MG TABLET

GLUCONORM Z XR 60 MG TABLET is a prescription medicine manufactured by Lupin Ltd., designed to manage Type 2 Diabetes Mellitus in adults.

• Composition

  • Active Ingredients: Each tablet contains Gliclazide 60 mg and Metformin Hydrochloride 500 mg.

• Uses GLUCONORM Z XR 60 MG TABLET is primarily used for the effective management of Type 2 Diabetes Mellitus, especially when diet, exercise, and weight loss alone are insufficient to control blood sugar levels. It works by:

  • Lowering blood sugar levels.
  • Improving the body's sensitivity to insulin.
  • Decreasing glucose production in the liver.
  • Delaying glucose absorption from the intestines.
  • Stimulating the pancreas to release more insulin.
  • It may also contribute to better cardiovascular health and reduce the risk of heart disease in diabetic patients, and in some cases, improve ovulation in Polycystic Ovary Syndrome (PCOS).

• Dosage and Administration This medication is for oral administration and should be taken exactly as prescribed by your doctor.

  • Typically taken once daily, preferably with food or just before meals, to reduce the risk of stomach upset and maximize effectiveness, often with the evening meal.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Your doctor will determine the appropriate dose based on your blood glucose levels and response to treatment. Do not alter the dosage without consulting your healthcare provider.

• Side Effects While GLUCONORM Z XR 60 MG TABLET is generally effective, some individuals may experience side effects:

  • Common Side Effects: Hypoglycemia (low blood sugar), dizziness, headache, nausea, vomiting, diarrhea, stomach pain, constipation, metallic taste in the mouth, and upper respiratory tract infection.
  • Serious (Rare) Side Effects: Lactic acidosis (a build-up of lactic acid in the blood) and vitamin B12 deficiency with long-term use.

• Precautions

  • Contraindications: Do not take this medicine if you are allergic to Gliclazide, Metformin, or any other ingredients. It is also contraindicated in individuals with severe kidney or liver disease, Type 1 diabetes, diabetic ketoacidosis, diabetic pre-coma or coma, chronic obstructive pulmonary disease, cardiac failure, or acute/chronic metabolic acidosis.
  • Alcohol: Avoid alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Organ Impairment: Caution is advised in patients with liver or kidney impairment; dose adjustments and close monitoring may be necessary.
  • Driving: Hypoglycemia can affect your ability to drive or operate machinery.
  • Regular monitoring of blood sugar levels is essential. Always carry a fast-acting source of glucose to counteract low blood sugar.

• Storage Store the medicine in a cool and dry place, away from direct sunlight, at a temperature between 10ºC to 25ºC or below 30ºC. Keep out of sight and reach of children.

What is GLUCONORM Z XR 60 MG TABLET used for?

GLUCONORM Z XR 60 MG TABLET is primarily used to manage Type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet, exercise, and weight loss alone are not sufficient. This medication also helps prevent serious diabetes-related complications such as kidney damage, blindness, nerve problems, heart attack, and stroke.

How does GLUCONORM Z XR 60 MG TABLET work?

This medicine is a combination of two antidiabetic drugs: Gliclazide (60 mg) and Metformin (500 mg). Gliclazide works by stimulating the pancreas to release more insulin and improves the body's response to insulin. Metformin reduces the amount of glucose produced by the liver, decreases glucose absorption from the intestines, and increases the body's sensitivity to insulin. The extended-release (XR) formulation ensures a gradual release of the medication, helping to maintain steady blood sugar levels throughout the day.

What is the usual dosage for GLUCONORM Z XR 60 MG TABLET?

GLUCONORM Z XR 60 MG TABLET is typically taken orally, usually once daily with a meal, often the evening meal, or as directed by your physician. It should be swallowed whole with a glass of water and not chewed, crushed, or broken. Your doctor will determine the appropriate dose and duration of treatment based on your individual blood sugar levels and response to the medication.

What are the possible side effects of GLUCONORM Z XR 60 MG TABLET?

Common side effects can include low blood sugar (hypoglycemia), nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and a metallic taste in the mouth. Other possible side effects are headache, dizziness, constipation, and upper respiratory tract infection. Some individuals may also experience weight gain. Serious but rare side effects can include lactic acidosis and vitamin B12 deficiency with long-term use.

Is GLUCONORM Z XR 60 MG TABLET safe during pregnancy or breastfeeding?

GLUCONORM Z XR 60 MG TABLET is generally not recommended and is considered unsafe during pregnancy due to potential risks to the unborn baby. Insulin is usually the preferred treatment for pregnant women with diabetes. It is also not advisable during breastfeeding, as it is unknown if the medicine or its metabolites pass into breast milk and could potentially harm the baby. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can GLUCONORM Z XR 60 MG TABLET be taken with other medications?

This medicine can interact with other medications, including other anti-diabetic agents (like insulin), certain blood pressure medications (ACE inhibitors), and non-steroidal anti-inflammatory drugs (NSAIDs). It is crucial to inform your doctor about all prescription and non-prescription medicines, supplements, and herbal products you are taking to avoid potential interactions and adverse effects.

What precautions should be taken while taking GLUCONORM Z XR 60 MG TABLET?

Do not stop taking this medicine without consulting your doctor, even if you feel better. Regular monitoring of your blood sugar levels is essential. Avoid alcohol consumption, as it can significantly increase the risk of low blood sugar (hypoglycemia) and a serious condition called lactic acidosis. Exercise caution if you have liver or kidney disease, as the medicine is contraindicated in severe cases. This medication may also cause dizziness due to changes in blood sugar, so be cautious when driving or operating machinery. Annual blood tests to monitor vitamin B12 levels and thyroid-stimulating hormone (TSH) may be recommended.

What happens if a dose of GLUCONORM Z XR 60 MG TABLET is missed?

If you miss a dose, take it as soon as you remember, especially if it's within a short timeframe (e.g., 30 minutes of a meal for some medications). However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can lead to a dangerous drop in blood glucose levels. Missing doses can lead to elevated blood sugar.

How should GLUCONORM Z XR 60 MG TABLET be stored?

Store GLUCONORM Z XR 60 MG TABLET in a cool, dry place at room temperature, typically below 30°C or between 10ºC to 25ºC, away from direct sunlight and moisture. Keep the medication out of the sight and reach of children.