Tobraza Xr 11mg Tab

TOBRAZA XR 11MG Tablet

TOBRAZA XR 11MG Tablet is an extended-release medication used for the treatment of various inflammatory and autoimmune conditions. It is manufactured by Glenmark Pharmaceuticals Ltd. or its division, Glenmark-Gracewell Care Div..

Composition The active ingredient in TOBRAZA XR 11MG Tablet is Tofacitinib 11mg. Tofacitinib belongs to a class of drugs called Janus kinase (JAK) inhibitors, which work by blocking the action of specific enzymes to reduce inflammation and suppress the immune system.

Uses TOBRAZA XR 11MG Tablet is prescribed for the treatment of:

• Moderate to severe rheumatoid arthritis
• Psoriatic arthritis
• Ankylosing spondylitis
• Moderate to severe ulcerative colitis This medicine helps decrease pain, tenderness, and swelling in the joints by reducing inflammation and can slow the progression of bone and joint damage. It is often used when previous therapies have been ineffective or poorly tolerated.

Dosage and Administration TOBRAZA XR 11MG Tablet should be taken orally, with or without food, exactly as prescribed by your doctor. It is advisable to take the tablet at the same time each day to maintain consistent medication levels. The extended-release tablet must be swallowed whole; it should not be chewed, crushed, or broken. Typical dosage for rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis is 11mg once daily. For ulcerative colitis, the initial dose may be 22mg once daily for at least 8 weeks, followed by 11mg once daily, as adjusted by your doctor. Do not stop taking this medicine without consulting your doctor, as your condition could worsen.

Side Effects Common side effects include:

• Upper respiratory tract infections
• Headache
• Diarrhea
• Nasopharyngitis
• Cold
• Nausea and vomiting More serious side effects can include an increased risk of severe infections (such as tuberculosis, fungal, bacterial, or viral infections), blood clots, tears in the stomach or intestine wall, and certain cancers (including lymphoma and skin cancers).

Precautions

• Infections: This medicine can weaken the immune system, increasing the risk of infections. Avoid contact with people who have contagious illnesses like chickenpox, measles, or flu.
• Age: Not recommended for use in children under 18 years of age.
• Pregnancy & Breastfeeding: Consult your doctor before using if pregnant or breastfeeding, as it may be unsafe.
• Organ Impairment: Use with caution in patients with kidney or liver disease, as dose adjustments may be necessary. It is generally not recommended for severe liver or kidney problems. Avoid or limit alcohol consumption due to potential liver damage risk.
• Medical History: Inform your doctor about any history of tuberculosis, shingles, hepatitis B or C, blood clots, or any type of cancer.
• Drug Interactions: Do not take TOBRAZA XR 11MG Tablet with other immunity-affecting medicines like tocilizumab, as this can significantly increase the risk of infections and complications.
• Monitoring: Regular blood tests to monitor liver function, kidney function, blood counts, and cholesterol levels may be required during treatment.

Storage Store TOBRAZA XR 11MG Tablet at room temperature, ideally below 30°C. Protect it from direct sunlight and moisture. Keep the medication out of reach and sight of children.

Here are some frequently asked questions about TOBRAZA XR 11MG TAB:

What is TOBRAZA XR 11MG TAB used for?

TOBRAZA XR 11MG TAB is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It helps to reduce pain, tenderness, and swelling in the joints by decreasing inflammation and can slow the progression of bone and joint damage. It is often prescribed when other treatments have not been effective or well-tolerated.

How does TOBRAZA XR 11MG TAB work?

TOBRAZA XR 11MG TAB contains Tofacitinib, which is a Janus kinase (JAK) inhibitor. It works by blocking the action of the Janus kinase enzyme, which plays a crucial role in the body's inflammatory response. By inhibiting this enzyme, the medicine decreases immune system activity and inflammation associated with certain autoimmune conditions.

What is the usual dosage for TOBRAZA XR 11MG TAB?

Your doctor will determine the appropriate dose and duration of TOBRAZA XR 11MG TAB based on your specific condition and how you respond to the medicine. It should be ingested whole with a glass of water, without chewing, crushing, or breaking it. It can be taken with or without food, preferably at the same time each day.

What are the possible side effects of TOBRAZA XR 11MG TAB?

Common side effects include upper respiratory tract infections, headache, diarrhea, nasopharyngitis (inflammation of the nose and pharynx), cold, nausea, and vomiting. More serious but less common side effects can include blood clots and tears in the stomach or intestine wall, which require urgent medical attention. TOBRAZA XR can also weaken the immune system, increasing the risk of serious infections and potentially certain cancers.

Is TOBRAZA XR 11MG TAB safe during pregnancy or breastfeeding?

TOBRAZA XR 11MG TAB is generally considered unsafe for use during pregnancy, as animal studies have shown harmful effects on the developing baby, and limited human data suggests potential harm. It is also probably unsafe to use during breastfeeding, as limited human data indicates the drug may pass into breast milk and harm the baby. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can TOBRAZA XR 11MG TAB be taken with other medications?

TOBRAZA XR 11MG TAB can interact with other medications, especially those that affect the immune system. You should not take it with other immunosuppressants or medications like tocilizumab, as combining them can significantly increase the risk of infections and complications. Always inform your doctor about all medicines, including over-the-counter drugs, herbal supplements, and vitamins you are currently taking.

What precautions should be taken while taking TOBRAZA XR 11MG TAB?

Before starting treatment, inform your doctor if you have an active infection, a history of tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots. TOBRAZA XR can weaken your immune system, making you more susceptible to infections. Regular blood tests may be needed to monitor liver function, kidney function, blood counts, and cholesterol levels. If you develop symptoms of an infection, contact your doctor immediately. Caution is also advised for patients with severe kidney or liver disease, and dose adjustments may be necessary.

What happens if a dose of TOBRAZA XR 11MG TAB is missed?

If you miss a dose of TOBRAZA XR 11MG TAB, take it as soon as you remember. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

How should TOBRAZA XR 11MG TAB be stored?

TOBRAZA XR 11MG TAB should be stored at room temperature, ideally below 30°C. Keep it in a cool, dry place, away from direct sunlight and moisture, as these can degrade the medicine. It should be kept out of the sight and reach of children.