Voglistar-plus 0.2 Tab

VOGLISTAR-PLUS 0.2 TAB by MANKIND-NOBELIS

Voglistar-Plus 0.2 Tablet is a combination medication primarily used in the management of type 2 diabetes mellitus in adults. Manufactured by Mankind Pharmaceuticals Ltd., this oral antidiabetic medicine helps control high blood sugar levels, especially when diet and exercise alone are not sufficient.

Composition:

Voglistar-Plus 0.2 Tablet contains two active ingredients:

• Metformin (500 mg): A biguanide that reduces glucose production by the liver, decreases glucose absorption from the intestines, and enhances the body's sensitivity to insulin, improving peripheral glucose uptake and utilization.
• Voglibose (0.2 mg): An alpha-glucosidase inhibitor that slows down the digestion and absorption of carbohydrates in the small intestine, thereby preventing sharp spikes in blood sugar levels after meals.

Uses:

Voglistar-Plus 0.2 Tablet is prescribed for:

• Managing type 2 diabetes mellitus in adults.
• Lowering post-meal blood sugar levels.
• Improving insulin sensitivity and reducing glucose production by the liver.
• Reducing the risk of diabetic complications such as kidney damage, eye damage, nerve problems, and cardiovascular complications, particularly in patients with existing heart disease.
• It is not indicated for type 1 diabetes or diabetic ketoacidosis.

Dosage and Administration:

The typical dosage guidance for Voglistar-Plus 0.2 Tablet is one tablet taken orally just before or with the first bite of each main meal (breakfast, lunch, and dinner). It is crucial to take the medicine regularly at the same time each day for maximum benefits. Tablets should be swallowed whole without crushing or chewing. Always adhere to the prescribed dosage and do not exceed it without consulting a doctor.

Side Effects:

Common side effects may include:

• Diarrhea
• Abdominal pain
• Nausea and Vomiting
• Decreased appetite
• Metallic taste in mouth
• Flatulence
• Skin rash
• Headache and Dizziness
• Low blood sugar levels (hypoglycemia)

Serious but less common side effects can include lactic acidosis and hepatitis, which require immediate medical attention.

Precautions:

• Alcohol: Avoid excessive alcohol intake as it increases the risk of lactic acidosis.
• Pregnancy & Breastfeeding: Caution is advised. It may be unsafe during pregnancy and could pass into breast milk. Consult a doctor.
• Kidney & Liver Conditions: Not recommended for patients with severe kidney disease or acute/chronic metabolic acidosis. Use with caution in those with liver disease or other kidney problems.
• Allergies: Do not take if allergic to Metformin, Voglibose, or any other components.
• Drug Interactions: Inform your doctor about all other medications, as interactions can occur with carbonic anhydrase inhibitors, cationic medicines, phenothiazines, thyroid products, estrogens, phenytoin, niacin, calcium channel blockers, and isoniazid.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is advisable.

Storage:

Store in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep out of sight and reach of children. The medicine should be stored below 30°C or between 10ºC to 25ºC.

Here are some frequently asked questions about VOGLISTAR-PLUS 0.2 Tablet:

What is VOGLISTAR-PLUS 0.2 Tablet used for?

VOGLISTAR-PLUS 0.2 Tablet is primarily used to treat Type 2 Diabetes Mellitus. It helps control high blood sugar levels, especially when diet and exercise alone are not sufficient. It may also help reduce the risk of diabetes complications such as kidney damage, nerve problems, and eye damage. Some sources also mention its use in managing Polycystic Ovary Syndrome (PCOS).

How does VOGLISTAR-PLUS 0.2 Tablet work?

This medicine contains two active ingredients: Voglibose and Metformin.

• Voglibose is an alpha-glucosidase inhibitor. It works by delaying the breakdown of complex carbohydrates into simple sugars (like glucose) in the intestine, which slows down the absorption of sugar into the bloodstream and prevents sharp rises in blood sugar levels after meals.
• Metformin is a biguanide. It reduces the amount of glucose produced by the liver, decreases the absorption of glucose from the intestines, and improves the body's sensitivity to insulin, allowing the body to use insulin more effectively.

What is the usual dosage for VOGLISTAR-PLUS 0.2 Tablet?

The dosage of VOGLISTAR-PLUS 0.2 Tablet is determined by your doctor based on your individual condition and response to treatment. It is typically taken orally, usually once or twice daily, with meals to help reduce gastrointestinal side effects. The specific tablet, VOGLISTAR-PLUS 0.2, contains 0.2 mg of Voglibose and 500 mg of Metformin. It's crucial to follow your doctor's instructions exactly.

What are the possible side effects of VOGLISTAR-PLUS 0.2 Tablet?

Common side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, stomach pain, flatulence (gas), changes in taste, and loss of appetite. These often resolve on their own over time. A rare but serious side effect of Metformin is lactic acidosis, which involves a buildup of lactic acid in the blood and can be dangerous, especially in patients with kidney, liver, or heart diseases. Hypoglycemia (low blood sugar) can occur, particularly when taken with other anti-diabetic medications, alcohol, or if meals are skipped.

Is VOGLISTAR-PLUS 0.2 Tablet safe during pregnancy or breastfeeding?

Caution is advised if you are pregnant or breastfeeding. It is important to consult your doctor before taking this medicine, as safety and effectiveness in these situations have not been fully established. Some sources recommend discontinuing use if pregnant or planning to become pregnant.

Can VOGLISTAR-PLUS 0.2 Tablet be taken with other medications?

VOGLISTAR-PLUS 0.2 Tablet can interact with various medications. It may increase the risk of hypoglycemia when combined with sulfonylureas or insulin. Other medications that may interact include certain antidepressants, anti-inflammatory drugs, diuretics, beta-2 agonists, corticosteroids, antifungals, antihypertensives, thyroid medications, estrogens, oral contraceptives, anticonvulsants, and carbonic anhydrase inhibitors. Always inform your doctor about all other medicines, supplements, or herbal products you are taking to avoid potential interactions.

What precautions should be taken while using VOGLISTAR-PLUS 0.2 Tablet?

• Do not take this medicine if you are allergic to any of its components.
• Inform your doctor if you have severe kidney or liver problems, acute metabolic acidosis, alcoholism, heart conditions, or severe infections.
• Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis.
• Adhere strictly to dietary recommendations and a regular exercise routine.
• Regular blood sugar monitoring is essential.
• Use with caution in elderly patients and those with chronic intestinal diseases.

What happens if a dose of VOGLISTAR-PLUS 0.2 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss multiple doses or are unsure, consult your doctor.

How should VOGLISTAR-PLUS 0.2 Tablet be stored?

Store the medicine in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.