Gibtulio Met 12.5 Mg /1000 Mg Tablet (10 Tab)

GIBTULIO MET 12.5 MG / 1000 MG TABLET

Name

• Brand Name: GIBTULIO MET 12.5 MG / 1000 MG TABLET
• Common Name: Empagliflozin and Metformin Hydrochloride Tablets

Composition

Gibtulio Met 12.5 mg / 1000 mg Tablet contains two active ingredients:

• Empagliflozin: 12.5 mg
• Metformin Hydrochloride: 1000 mg

Uses

Gibtulio Met is a combination medicine primarily used to treat type 2 diabetes mellitus in adults. It is prescribed as an adjunct to diet and exercise to improve glycemic control.

• It helps control blood sugar levels by removing excess glucose from the body through urine (Empagliflozin) and by decreasing glucose production in the liver while improving the body's sensitivity to insulin (Metformin).
• This medication may also help reduce the risk of hospitalization due to heart failure in patients with established cardiovascular disease and type 2 diabetes.
• Controlling high blood sugar levels helps prevent serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs.

Dosage and Administration

• Gibtulio Met 12.5 mg / 1000 mg Tablet is typically taken orally, once or twice daily with meals to minimize gastrointestinal side effects.
• The dosage is determined by your doctor based on individual needs and response to treatment.
• Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it.
• Consistency is key for optimal blood sugar control, so it is important to take it regularly and as prescribed, preferably at the same time each day.

Side Effects

Common side effects may include:

• Nausea, vomiting, diarrhea, abdominal pain
• Urinary tract infections (UTIs)
• Genital fungal infections (e.g., yeast infections)
• Headache, dizziness
• Loss of appetite, metallic taste
• Increased urination
• Nasopharyngitis (inflammation of the nose and throat)

Serious side effects can include:

• Lactic acidosis (a rare but serious condition)
• Hypoglycemia (low blood sugar), especially when combined with insulin or other antidiabetic medicines
• Dehydration
• Ketoacidosis

Precautions

• Contraindications: This medicine is contraindicated in patients with severe kidney disease, metabolic acidosis (including diabetic ketoacidosis), type 1 diabetes mellitus, and severe liver disease. It is generally not recommended for use in pregnant or breastfeeding women.
• Alcohol Consumption: Avoid excessive alcohol intake as it can increase the risk of lactic acidosis.
• Dehydration: It is important to stay hydrated while taking this medicine. Temporary discontinuation may be advised if conditions like vomiting, diarrhea, or fever lead to dehydration.
• Surgery: SGLT2 inhibitors (like empagliflozin) should be stopped temporarily before scheduled surgery to lessen the risk of ketoacidosis.
• Drug Interactions: Inform your doctor about all other medications you are taking, as interactions can occur with carbonic anhydrase inhibitors, medicines that reduce metformin clearance (e.g., ranolazine, cimetidine), insulin, or insulin secretagogues.
• Kidney and Liver Function: Regular monitoring of kidney and liver function may be necessary.

Storage

Store Gibtulio Met 12.5 mg / 1000 mg Tablet in a cool and dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets. Store at room temperature, typically between 10ºC to 25ºC or below 30ºC.

Gibtulio Met 12.5 mg/1000 mg Tablet is a combination medication used to manage Type 2 Diabetes Mellitus. It contains Empagliflozin and Metformin as its active ingredients.

Here are some frequently asked questions about Gibtulio Met 12.5 mg/1000 mg Tablet:

What is Gibtulio Met used for?

Gibtulio Met 12.5 mg/1000 mg Tablet is primarily used, along with diet and exercise, to improve blood sugar control in adults with Type 2 Diabetes Mellitus. It is prescribed when diabetes is not adequately controlled by metformin alone or by metformin in combination with other anti-diabetic medicines. Additionally, it can help reduce the risk of hospitalization due to heart failure and may offer renal protection for patients with Type 2 diabetes and established cardiovascular disease.

How does Gibtulio Met work?

Gibtulio Met combines two anti-diabetic medicines: Empagliflozin and Metformin.

• Empagliflozin is a sodium-glucose co-transporter-2 (SGLT-2) inhibitor. It works by blocking the reabsorption of glucose by the kidneys, leading to the removal of excess sugar from the body through urine, thereby lowering blood glucose levels.
• Metformin belongs to the biguanide class. It primarily works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin, which helps the body utilize sugar more effectively. Together, these actions more effectively lower blood glucose.

What is the usual dosage of Gibtulio Met?

The dosage of Gibtulio Met is determined by your doctor based on your medical condition and response to treatment. It is usually taken orally once or twice daily. It can be taken with or without food, but taking it with meals can help prevent stomach upset. Always follow your doctor's instructions and do not change the prescribed dosage without consulting them.

What are the possible side effects of Gibtulio Met?

Common side effects may include frequent urination, urinary tract infections (UTIs), genital fungal infections (yeast infections), nausea, vomiting, diarrhea, stomach ache, mild skin rash or itchy skin, and headache. A rare but serious side effect associated with metformin is lactic acidosis, symptoms of which can include unusual muscle pain, trouble breathing, weakness, and irregular heartbeats. Staying hydrated and maintaining good hygiene can help manage some side effects. If any side effects persist or worsen, consult your doctor.

Is Gibtulio Met safe during pregnancy or breastfeeding?

Gibtulio Met is generally not recommended during pregnancy and is probably unsafe to use while breastfeeding. Empagliflozin is not recommended in pregnancy as it is not clear if it can harm an unborn baby. Metformin can be excreted into breast milk. It is crucial to consult your doctor to discuss the risks and benefits and explore safer alternatives if you are pregnant, planning to conceive, or breastfeeding.

Can Gibtulio Met be taken with other medications?

Gibtulio Met can interact with various medications. Inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential interactions. Specific interactions include:

• NSAIDs (e.g., ibuprofen, naproxen): May impair kidney function and increase the risk of lactic acidosis.
• Diuretics (e.g., furosemide): May decrease kidney function and increase the risk of lactic acidosis.
• Insulin or insulin secretagogues: May increase the risk of hypoglycemia (low blood sugar).
• Cationic medicines (e.g., amiloride, digoxin, morphine): May interact with metformin and increase the risk of lactic acidosis.
• Lithium: Gibtulio Met may lower lithium levels in the blood.
• Alcohol: Avoid or limit alcohol consumption as it can increase the risk of lactic acidosis and worsen side effects.

What precautions should be taken while using Gibtulio Met?

• Type 1 Diabetes: This medicine is not for Type 1 Diabetes Mellitus.
• Kidney/Liver Disease: It should not be taken if you have severe kidney or liver disease. Your doctor will monitor kidney function, especially in elderly patients.
• Dehydration: Discontinue use temporarily if you have conditions that may lead to dehydration (e.g., vomiting, diarrhea, fever). Stay well-hydrated.
• Alcohol: Avoid excessive alcohol intake due to increased risk of lactic acidosis.
• Hypoglycemia: While less likely to cause low blood sugar on its own, the risk increases when taken with insulin or other anti-diabetic medications.
• Hygiene: Practice good genital hygiene to minimize the risk of fungal infections.
• Allergies: Do not consume if you are allergic to empagliflozin, metformin, or any other components.

What happens if a dose is missed?

If you miss a dose of Gibtulio Met, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects. If you miss multiple doses or are unsure, consult your doctor or pharmacist.

How should Gibtulio Met be stored?

Gibtulio Met tablets should be stored in a cool and dry place, away from direct sunlight. The ideal storage temperature is below 30°C. Keep the container tightly closed to protect the medicine from moisture and light. Always keep this medicine out of the sight and reach of children.