Sebifin Tablet (15 Tab)

SEBIFIN TABLET (15 TAB) by SUN PHARMACEUTICAL IND.LTD.

Name

• Brand Name: Sebifin Tablet
• Common Name/Active Ingredient: Terbinafine

Composition

Sebifin Tablet contains Terbinafine (as hydrochloride) 250 mg as its active ingredient. Terbinafine is an antifungal medication that works by damaging the fungal cell membranes, which are essential for the survival and growth of the fungi, thereby killing the infection-causing fungus.

Uses

Sebifin Tablet is prescribed to treat a wide range of fungal infections affecting the skin, hair, and nails. These include:

• Fungal infections of the fingernails and toenails (onychomycosis).
• Tinea capitis (scalp ringworm).
• Tinea corporis (body ringworm).
• Tinea cruris (jock itch/fungal infection of the groin area).
• Tinea pedis (athlete's foot/fungal infection of the feet).
• It is also used for resistant fungal infections.

Dosage and Administration

The usual dose of Sebifin Tablet is one 250 mg tablet taken once daily. It can be taken with or without food, though taking it after a light meal may help if it causes stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. The duration of treatment varies, typically 2 to 6 weeks for skin infections and 6 weeks to 6 months for nail infections, as advised by your doctor. It is crucial to complete the entire prescribed course of treatment.

Side Effects

Common side effects include:

• Headache
• Taste change or loss of taste
• Nausea, vomiting, diarrhea, stomach pain, indigestion, or loss of appetite
• Skin rash, itching
• Joint or muscle pain
• Dizziness
• Abnormal liver enzyme levels

Serious side effects (rare) may include:

• Signs of liver problems (e.g., yellowing of skin/eyes, dark urine, pale stools, persistent unexplained nausea, unusual tiredness).
• Severe allergic reactions (e.g., difficulty breathing, swelling of face/tongue/throat).
• Severe skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis.

Precautions

• Do not take Sebifin Tablet if you are allergic to terbinafine or have existing liver problems.
• Consult your doctor if you are pregnant, planning to conceive, or breastfeeding (it is not recommended for breastfeeding mothers as it may be excreted in human milk).
• Inform your doctor if you have kidney problems, psoriasis, or other autoimmune skin conditions.
• Sebifin Tablet may interact with certain medications, including some antidepressants, medicines for Parkinson's disease, beta-blockers, cimetidine, rifampicin, oral contraceptives, warfarin, and cyclosporine.
• Avoid or limit sun exposure as Sebifin Tablet may increase skin sensitivity to sunlight.
• Avoid driving or operating machinery if you experience dizziness.
• Avoid alcohol consumption as it may increase the risk of liver damage.
• Regular monitoring of liver function may be required during treatment.

Storage

Store Sebifin Tablet in a cool, dry place, protected from light and moisture, ideally at temperatures between 10ºC to 25ºC or below 30ºC. Keep it out of the sight and reach of children. Do not store it in the bathroom or near a sink.

Here are frequently asked questions about SEBIFIN TABLET:

What is SEBIFIN TABLET used for?

SEBIFIN TABLET is an antifungal medicine primarily used to treat various fungal infections of the skin, hair, and nails. This includes fungal infections of the fingernails and toenails (onychomycosis), scalp ringworm (tinea capitis), athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm of the body (tinea corporis).

How does SEBIFIN TABLET work?

SEBIFIN TABLET contains the active ingredient terbinafine. Terbinafine works by damaging the cell membranes of the fungi, which are crucial for their survival and growth. By inhibiting a key enzyme in the fungal sterol biosynthesis, it weakens the fungal cells and ultimately kills the infection-causing fungi.

What is the usual dosage of SEBIFIN TABLET?

The usual adult dosage for SEBIFIN TABLET is one 250 mg tablet once daily. The duration of treatment varies depending on the type and location of the fungal infection; for skin infections, it's typically 2 to 6 weeks, while nail infections may require 6 weeks to 6 months. It can be taken with or without food, swallowed whole with water, and should be taken at the same time each day for best effect.

What are the possible side effects of SEBIFIN TABLET?

Common side effects may include diarrhoea, stomach pain, headache, nausea, vomiting, rash, indigestion, itching, joint pain, muscle pain, and a change or loss of taste. More serious but rare side effects can include liver problems (yellowing of skin or eyes, dark urine, stomach pain), severe allergic skin reactions (like Stevens-Johnson syndrome), or a decrease in blood cell counts. Consult your doctor if any side effects persist or worsen.

Is SEBIFIN TABLET safe during pregnancy or breastfeeding?

During pregnancy, SEBIFIN TABLET is generally advised to be used only if the doctor determines the benefits outweigh the potential risks, as there are limited studies in humans, and animal studies have shown harmful effects on the developing baby. For breastfeeding mothers, it is not recommended as terbinafine can pass into breast milk and may harm the infant. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can SEBIFIN TABLET be taken with other medications?

SEBIFIN TABLET can interact with several other medications. It is crucial to inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking. Specific interactions may occur with other antifungals, blood-thinning medicines (e.g., warfarin), some medicines for high blood pressure (e.g., beta-blockers), cimetidine (for stomach ulcers), rifampicin (an antibiotic), oral contraceptives, cyclosporine, and certain medicines for depression, Parkinson's disease, or other mental disorders.

What precautions should be taken while using SEBIFIN TABLET?

Avoid SEBIFIN TABLET if you are allergic to terbinafine or its ingredients. Caution is advised for individuals with liver or kidney problems; your doctor may need to adjust the dose or monitor your liver function regularly. It is best to avoid alcohol during treatment due to an increased risk of liver damage. Limit sun exposure, as the medicine may increase skin sensitivity. If you experience dizziness, avoid driving or operating machinery. Always complete the full course of treatment, even if symptoms improve, to ensure the infection is fully cleared and to prevent recurrence.

What happens if a dose of SEBIFIN TABLET is missed?

If you miss a dose of SEBIFIN TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SEBIFIN TABLET be stored?

SEBIFIN TABLET should be stored at room temperature, ideally between 10°C and 25°C, or below 30°C. Keep it in a clean, dry place, protected from moisture, direct sunlight, and heat. Ensure the medicine is kept out of the sight and reach of children and pets.