Roliten 2 Mg Tablet (10 Tab)

ROLITEN 2 MG TABLET

Name:

• Brand Name: Roliten 2 mg Tablet
• Common Name: Tolterodine (as Tolterodine Tartrate)

Composition: ROLITEN 2 MG TABLET contains Tolterodine 2 mg as its active ingredient. It belongs to a class of medications known as antimuscarinics or anticholinergics.

Uses: This medicine is primarily used for the symptomatic treatment of overactive bladder (OAB) syndrome. OAB is characterized by involuntary contractions of the bladder muscles, leading to symptoms such as:

• Frequent urination
• Urgent need to urinate (urinary urgency)
• Inability to control urination (urge incontinence)

Tolterodine works by relaxing the urinary bladder muscles, thereby reducing these urgent, frequent, or uncontrolled urinations and improving bladder control.

Dosage and Administration:

• The recommended dose for adults, including the elderly, is typically 2 mg twice daily.
• The tablet should be swallowed whole with a glass of water, and should not be crushed, chewed, or broken.
• It can be taken with or without food, but it is advisable to take it at the same time each day for best results.
• For patients with impaired liver function or severely impaired renal function (GFR<30 ml/min), the recommended dose is 1 mg twice daily.
• Do not stop taking the medicine abruptly without consulting a doctor, as this may worsen symptoms.

Side Effects: Common side effects may include:

• Dryness in the mouth
• Headache
• Constipation
• Dizziness
• Sleepiness/Drowsiness
• Blurred vision
• Dry skin
• Diarrhea
• Indigestion/Dyspepsia
• Fatigue

Serious side effects, though rare, can include signs of angioedema (swelling of the face, tongue, or throat, difficulty swallowing, itchy skin rash, and breathing issues) which require immediate medical attention.

Precautions:

• Allergies: Do not take if allergic to Tolterodine or any of its components.
• Medical Conditions: Inform your doctor if you have glaucoma (especially uncontrolled narrow-angle glaucoma), urinary retention (inability to empty the bladder completely), gastric retention (slow emptying of the stomach), severe liver or kidney problems, heart rhythm problems (including QT prolongation), gastrointestinal obstructive disorders, severe ulcerative colitis, toxic megacolon, autonomic neuropathy, or myasthenia gravis.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding without consulting a doctor, as its safety in these conditions is uncertain and it may pass into breast milk.
• Alcohol: Avoid alcohol consumption as it may increase side effects like drowsiness and dizziness.
• Driving and Machinery: This medicine may cause dizziness, drowsiness, or blurred vision. Avoid driving or operating heavy machinery until you know how it affects you.
• Lactose Intolerance: Roliten 2 mg Tablet contains lactose, so inform your doctor if you have sugar intolerance.
• Children: This medicine is not recommended for use in patients less than 18 years of age.
• Overdose: Symptoms of overdose may include dry mouth or confusion. Consult a doctor immediately if an overdose is suspected.

Storage:

• Keep out of sight and reach of children.
• Store below 30°C.
• Store in a cool and dry place, protected from moisture and sunlight.

Frequently Asked Questions about ROLITEN 2 MG TABLET

What is Roliten 2 mg Tablet used for?

Roliten 2 mg Tablet is primarily used to treat symptoms of an overactive bladder (OAB) syndrome. This condition is characterized by uncontrollable bladder muscle contractions, leading to symptoms such as frequent urination, an urgent need to urinate, and an inability to control urination (urinary incontinence).

How does Roliten 2 mg Tablet work?

Roliten 2 mg Tablet contains Tolterodine, which belongs to a class of medications called antimuscarinics or muscarinic receptor blockers. It works by relaxing the muscles of the urinary bladder. By blocking muscarinic receptors in the bladder wall, Tolterodine inhibits the action of acetylcholine, a neurotransmitter that causes bladder muscles to contract. This reduction in involuntary bladder contractions helps prevent urgent, frequent, or uncontrolled urination, increases bladder capacity, and improves control over urination.

What is the usual dosage of Roliten 2 mg Tablet?

The recommended adult dose of Roliten 2 mg Tablet is typically 2 mg twice daily. However, the exact dose and duration of treatment will be determined by your doctor based on your medical condition and response to the medicine. It should be swallowed whole with a glass of water, with or without food, preferably at the same time each day. In cases of troublesome side effects, the dose may be reduced to 1 mg twice daily.

What are the possible side effects of Roliten 2 mg Tablet?

Common side effects of Roliten 2 mg Tablet include dry mouth, headache, constipation, sleepiness, dizziness, blurred vision, and dry skin. Other possible side effects can include indigestion, abdominal pain, diarrhea, fatigue, and heartburn. Most of these side effects are temporary and usually resolve over time. However, if they persist or worsen, it is advisable to consult your doctor. Serious but less common side effects can include angioedema (swelling of the face, tongue, or throat) and QT prolongation (a type of heart rhythm problem).

Is Roliten 2 mg Tablet safe during pregnancy or breastfeeding?

Roliten 2 mg Tablet is generally not recommended during pregnancy as there is limited data on its use in pregnant women and animal studies have shown reproductive toxicity. For breastfeeding women, the drug is probably unsafe to use as there is no data concerning its excretion into human milk, and long-term use might reduce milk production. It is crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.

Can Roliten 2 mg Tablet be taken with other medications?

Roliten 2 mg Tablet can interact with certain other medications. It is not recommended to use it simultaneously with potent CYP3A4 inhibitors like macrolide antibiotics (e.g., erythromycin, clarithromycin) and antifungal agents (e.g., ketoconazole, itraconazole), as this can increase the concentration of Tolterodine in the body and potentially lead to overdose. Concomitant use with other antimuscarinic drugs may result in more pronounced effects and side effects. Roliten Tablet can also reduce the effects of prokinetics like metoclopramide and cisapride. Always inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.

What precautions should be taken?

Before taking Roliten 2 mg Tablet, inform your doctor if you have allergies to any of its components, glaucoma, urinary retention, gastric retention, kidney disease, liver disease, bladder blockage, or a history of heart rhythm problems (including QT prolongation). As the medicine may cause dizziness or blurred vision, avoid driving or operating heavy machinery until you know how it affects you. Alcohol consumption should be avoided as it can exacerbate side effects like dizziness and drowsiness. Patients with lactose intolerance should also inform their doctor as Roliten 2 mg Tablet contains lactose.

What happens if a dose of Roliten 2 mg Tablet is missed?

If you miss a dose of Roliten 2 mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should it be stored?

Roliten 2 mg Tablet should be stored at room temperature, ideally between 20°C to 25°C (68°F to 77°F). Keep it in a dry place, away from direct sunlight and moisture, and out of sight and reach of children. Always check the expiry date before using the medicine.