Folinal Tab

FOLINAL TAB by ALEMBIC PHARMACEUTICALS LIMITED

Name

Brand Name: Folinal Tablet (also known as New Folinal Tablet, Folinal 1mg Tablet, Folinal 5mg Tablet)

Composition

Active Ingredient: L-Methylfolate (an activated form of Folic Acid, Vitamin B9) Folinal Tablet is typically available in strengths such as 1mg or 5mg of L-methylfolate.

Uses

Folinal Tablet is primarily prescribed to treat and prevent conditions related to folic acid deficiency. These include:

• Anemia: Specifically megaloblastic anemia and low red blood cell levels due to folic acid deficiency, chronic diseases, or inadequate diet.
• Pregnancy Support: To prevent neural tube defects (NTDs) in developing fetuses and support overall fetal growth and development. It is recommended before and during pregnancy.
• Nutritional Supplementation: To address low folic acid levels resulting from poor nutrition, malabsorption syndrome, or recovery from surgery.

Dosage and Administration

Take Folinal Tablet orally as directed by your physician. It can be consumed with or without food; however, some sources suggest taking it after meals to enhance absorption and minimize stomach upset. Swallow the tablet whole with water; do not crush, chew, or break it. The dosage and duration of treatment depend on the medical condition and individual needs, often prescribed once daily.

Side Effects

Common side effects may include:

• Stomach upset
• Loss of appetite
• Nausea
• Bloating and flatulence (gas)

Serious but rare side effects could include:

• Allergic reactions (rash, itching, swelling, bronchospasm)
• Fever, weakness, and general discomfort
• Mood/mental changes (in cases of overdose)

Precautions

• Inform your doctor about any known allergies to the medicine or any of its components.
• Disclose any pre-existing medical conditions such as vitamin B12 deficiency, pernicious anemia, sickle cell anemia, stomach ulcers, bipolar disorder, or liver/kidney disease.
• Avoid consuming alcohol, as it may reduce folic acid absorption and worsen side effects.
• Certain substances like antacids, dairy products, tea, and coffee may affect the action of Folinal Tablet; discuss these with your doctor.
• If you are pregnant or breastfeeding, consult your doctor before taking this medicine, though it is generally considered safe if prescribed.
• Folinal Tablet should not be used alone to treat anemia caused by vitamin B12 deficiency, as it may mask the symptoms of B12 deficiency.

Storage

Store Folinal Tablet in a cool, dry place, away from direct sunlight. Keep it out of the sight and reach of children. Maintain storage temperatures below 30°C. Ensure the container is tightly closed to protect from moisture.

What is Folinal Tab used for?

Folinal Tab, which contains L-methyl folate (an activated form of folic acid or Vitamin B9), is primarily used to treat and prevent various types of anemia, particularly those caused by folic acid deficiency, including megaloblastic anemia and anemia during pregnancy. It is also crucial for preventing neural tube defects in developing babies when taken by pregnant women, and supports overall fetal development. Additionally, it can be used as a supplement to address nutritional deficiencies, especially during pregnancy, breastfeeding, after surgery, or in conditions of nutritional malabsorption.

How does Folinal Tab work?

Folinal Tab works by providing L-methyl folate, an activated form of folic acid, which is essential for the body's synthesis of DNA and amino acids. This process is crucial for cell division and the production of healthy red blood cells. By boosting red blood cell production, Folinal Tab helps to carry oxygen throughout the body and ensures adequate hemoglobin levels, thus combating anemia.

What is the usual dosage of Folinal Tab?

The dosage of Folinal Tab is determined by a doctor based on the individual's medical condition. It is commonly advised to take it once daily, with or without food. For the prevention of neural tube defects during pregnancy, a dose of 4 or 5 mg daily, starting before pregnancy and continuing through the first trimester, may be prescribed. For general prophylaxis of megaloblastic anemia in pregnancy, a dose of 0.2-0.5 mg daily might be recommended. It should be swallowed whole and not crushed, chewed, or broken.

What are the possible side effects of Folinal Tab?

Folinal Tab is generally well-tolerated. However, some common side effects may include stomach upset, loss of appetite, nausea, bloating or gas, and an unpleasant taste in the mouth. In rare cases, more severe reactions like headache, fever, weakness, itching, rash, or difficulty breathing have been reported. If any side effects persist or worsen, it is advisable to consult a doctor.

Is Folinal Tab safe during pregnancy or breastfeeding?

Folinal Tab is generally considered safe for consumption by pregnant and breastfeeding women. It is particularly important during pregnancy to ensure proper fetal growth and development and to reduce the risk of neural tube defects. However, it is crucial to consult a doctor for an appropriate dose based on individual clinical conditions before taking this medicine during pregnancy or breastfeeding.

Can Folinal Tab be taken with other medications?

Folinal Tab generally has few interactions with prescription drugs. However, it can interact with certain medications, such as methotrexate (used for cancer and autoimmune diseases) and some anticonvulsants (used to control seizures). These interactions may affect the efficacy of the medications or increase the risk of side effects. It is important to inform your doctor about all medications and supplements you are taking to prevent potential interactions. Excessive alcohol consumption can also decrease the absorption and effectiveness of Folinal Tab and should be avoided.

What precautions should be taken while taking Folinal Tab?

Before taking Folinal Tab, inform your doctor if you have any known allergies to its components or if you have certain medical conditions such as cancer, pernicious anemia (Vitamin B12 deficiency), sickle cell anemia, stomach ulcers, liver disease, or kidney disease (especially if undergoing hemodialysis). Caution is also advised in children, and use should be only if recommended by a doctor. Avoid excessive alcohol consumption as it can reduce the absorption of folic acid. If you have planned surgery, you may be asked to stop taking it 2-3 weeks prior.

What happens if a dose of Folinal Tab is missed?

If you miss a dose of Folinal Tab, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose or extra doses to make up for a missed one. It is important to consult your doctor for clarification if you frequently miss doses.

How should Folinal Tab be stored?

Folinal Tab should be stored in a cool, dry place, away from direct sunlight. It should be kept out of the reach and sight of children. Ensure the medicine is not used past its expiry date. Typically, it should be stored at temperatures between 10ºC to 25ºC or below 30ºC.