Canditral Sb 130 Mg Capsule (10 Cap)

CANDITRAL SB 130 MG CAPSULE

Canditral SB 130 Capsule, manufactured by Glenmark Pharmaceuticals Ltd., is an antifungal medication primarily used to treat various fungal infections.

• Name: Canditral SB 130 Capsule
• Composition: Each capsule contains Itraconazole 130 mg.
• Uses: Canditral SB 130 Capsule is prescribed for a wide range of fungal and yeast infections. It effectively treats infections of the mouth, throat (oral thrush), vagina (vaginal thrush), skin (e.g., ringworm, athlete's foot, jock itch), fingernails, and toenails. It is also used for more serious systemic fungal infections such as aspergillosis, blastomycosis, and histoplasmosis, particularly in immunocompromised patients. It works by inhibiting the production of ergosterol, a vital component of fungal cell membranes, thus stopping fungal growth and leading to cell death.
• Dosage and Administration: This medicine should be taken as prescribed by your doctor. It is typically taken orally with food to enhance absorption, swallowed whole with water, and not crushed or chewed. The dose and duration depend on the type and severity of the infection, and it's crucial to complete the full course of treatment even if symptoms improve to prevent recurrence.
• Side Effects: Common side effects include nausea, headache, stomach pain, vomiting, dizziness, and diarrhea. Serious side effects can include liver problems (yellowing of skin/eyes, dark urine, severe fatigue, stomach pain), nerve pain (tingling, numbness, weakness in limbs), and hearing loss. Consult your doctor if any side effects persist or worsen.
• Precautions:
  • Pregnancy and Breastfeeding: It is generally not recommended during pregnancy due to potential harm to the unborn baby and should be avoided while breastfeeding as it may pass into breast milk.
  • Liver/Kidney/Heart Conditions: Use with caution in patients with kidney or liver disease, or heart problems such as heart failure. Regular liver function monitoring may be required for prolonged treatment.
  • Drug Interactions: Inform your doctor about all medicines you are taking, especially antacids (take 2 hours after Canditral SB), certain cholesterol-lowering drugs, and other antifungals. Avoid alcohol consumption as it may increase the risk of liver damage.
  • Driving: May cause dizziness or blurred vision; caution is advised when driving or operating machinery.
• Storage: Store in a cool, dry place away from moisture and direct sunlight, not exceeding 30 degrees Celsius. Keep out of reach of children.

CANDITRAL SB 130 MG CAPSULE (by GLENMARK PHARMACEUTICALS LTD.) contains Itraconazole as its active ingredient, an antifungal medication used to treat various fungal infections.

What is Canditral SB 130 mg Capsule used for?

Canditral SB 130 mg Capsule is primarily used to treat a variety of fungal and yeast infections in the body. These can include infections of the mouth, throat, vagina, skin, fingernails, toenails, and internal organs like the lungs. Specific conditions it treats include aspergillosis, blastomycosis, histoplasmosis, sporotrichosis, and candidiasis.

How does Canditral SB 130 mg Capsule work?

The active ingredient, Itraconazole, works by inhibiting the production of ergosterol, a vital component of fungal cell membranes. By disrupting ergosterol synthesis, the drug weakens and damages the fungal cell membrane, leading to the leakage of cell contents and ultimately killing the fungi, thus clearing the infection.

What is the usual dosage for Canditral SB 130 mg Capsule?

The dosage of Canditral SB 130 mg Capsule varies depending on the type and severity of the fungal infection being treated. It is generally taken once or twice daily, but for certain conditions like onychomycosis (fungal nail infections), a "pulse dosing" regimen (higher doses for one week every month) may be prescribed. It is crucial to follow your doctor's instructions precisely and take the capsules with a full meal to enhance absorption. Doses exceeding 200 mg daily are often divided into two doses.

What are the possible side effects of Canditral SB 130 mg Capsule?

Common side effects can include gastrointestinal disturbances such as nausea, diarrhea, stomach pain, vomiting, and constipation. Other frequently reported side effects are headache, dizziness, increased blood pressure, skin rash, itching, and changes in menstrual periods. More serious, though rare, side effects can include severe liver problems, congestive heart failure (symptoms like shortness of breath, rapid weight gain, swelling), and nerve problems (numbness, tingling, burning sensation). If you experience any severe or persistent side effects, contact your doctor immediately.

Is Canditral SB 130 mg Capsule safe during pregnancy or breastfeeding?

Canditral SB 130 mg Capsule (Itraconazole) is generally not recommended during pregnancy and is classified as pregnancy category C by the FDA, meaning animal studies have shown adverse effects on fetal development, but there is inadequate data on human development. It is contraindicated for onychomycosis in pregnant patients or those planning to become pregnant, and effective birth control should be used during treatment and for two months after the last dose. For breastfeeding mothers, limited data suggest that itraconazole passes into breast milk in small amounts. An alternative medication may be preferred, especially when nursing newborns or preterm infants. Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Can Canditral SB 130 mg Capsule be taken with other medications?

Itraconazole can interact with a large number of other medications, and some combinations are contraindicated due to the risk of serious side effects, including life-threatening heart rhythm problems. It is a potent inhibitor of CYP3A4 enzymes, which are involved in metabolizing many drugs. It is crucial to inform your doctor about all prescription, over-the-counter, herbal, and vitamin supplements you are taking. Some examples of drugs that should be avoided or used with extreme caution include certain medications for cholesterol (e.g., lovastatin, simvastatin), blood pressure (e.g., felodipine, nisoldipine), heart rhythm (e.g., quinidine, disopyramide), benzodiazepines (e.g., oral midazolam, triazolam), and certain opioids (e.g., fentanyl, methadone). Antacids or other stomach acid reducers should be taken at least 2 hours before or 2 hours after Canditral SB 130 mg Capsule, as stomach acid is needed for proper absorption of itraconazole capsules.

What precautions should be taken while using Canditral SB 130 mg Capsule?

Inform your doctor if you have a history of heart failure, liver disease, or kidney disease, as these conditions may require special monitoring or contraindicate the use of itraconazole. Regular blood tests to monitor liver function are recommended, especially during long-term treatment. If you experience symptoms such as severe stomach pain, dark urine, or yellowing of the skin or eyes, contact your doctor immediately. This medication may cause dizziness or blurred vision, so avoid driving or operating heavy machinery until you know how it affects you.

What happens if a dose of Canditral SB 130 mg Capsule is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Canditral SB 130 mg Capsule be stored?

Canditral SB 130 mg Capsules should be stored in their original container at room temperature, typically between 20°C and 25°C (68°F and 77°F). Keep the medicine away from heat, moisture, and direct light. Ensure it is kept out of the reach of children and pets. Do not use outdated or no longer needed medicine.