Nailrox 1% Cream 50 Gm

NAILROX 1% CREAM 50 GM

NAILROX 1% CREAM 50 GM is a topical antifungal medication manufactured by Intas Pharmaceuticals Ltd., primarily used for managing various fungal infections of the skin and nails.

Composition The active ingredient in NAILROX Cream is Ciclopirox (1% w/w). Ciclopirox works by disrupting the synthesis of DNA and RNA within fungal cells, inhibiting metal-dependent enzymes, and chelating trivalent cations essential for fungal cell membrane synthesis and division, ultimately preventing the growth and spread of fungi.

Uses NAILROX Cream is prescribed for the treatment of various superficial fungal skin and nail infections. These include:

• Athlete's foot (Tinea pedis)
• Jock itch (Tinea cruris)
• Ringworm of the body (Tinea corporis)
• Yeast infection of the skin (Cutaneous candidiasis)
• Pityriasis versicolor
• Fungal nail infections
• Seborrheic dermatitis of the scalp (when formulated as a shampoo)

Dosage and Administration NAILROX Cream is for external use only. The affected skin area should be cleaned and dried thoroughly before application. A thin layer of the cream should be gently spread over the affected area and surrounding skin, and massaged until absorbed. Hands should be washed before and after application, unless the hands are the treatment site. The typical dosage and duration will vary based on the specific condition and should be followed as directed by a healthcare professional. It is crucial to continue using the cream for the prescribed duration even if symptoms improve to prevent recurrence.

Side Effects Common side effects at the application site may include:

• Burning sensation
• Itching
• Redness
• Pain and irritation
• Skin rash or hives

Serious side effects, though rare, may include severe irritation or allergic reactions. If severe discomfort or an allergic reaction occurs, discontinue use and consult a doctor.

Precautions

• Avoid contact with eyes, mouth, nose, and other mucous membranes. In case of accidental contact, rinse thoroughly with plenty of water.
• Do not use if allergic to ciclopirox or any other ingredients in the cream.
• Caution is advised for pregnant and breastfeeding women; consult a doctor before use.
• Do not apply to open wounds or damaged skin, as this may increase absorption.
• NAILROX Cream is generally not recommended for children below 10 years of age unless advised by a doctor.
• Avoid covering the treated area with bandages or dressings unless specifically instructed by a doctor, as this may increase absorption and side effects.
• There are no known significant drug-drug or drug-food interactions with topical Ciclopirox.

Storage Always store NAILROX Cream below 25°C or 30°C in a cool, dry area, away from direct sunlight and moisture. Keep the tube tightly closed when not in use and ensure it is out of sight and reach of children. Do not use the medicine after the expiry date or if there are visible signs of deterioration.

What is NAILROX 1% CREAM used for?

NAILROX 1% CREAM is a topical antifungal medication used to treat a variety of superficial fungal skin infections. These include athlete's foot (Tinea pedis), jock itch (Tinea cruris), ringworm of the body (Tinea corporis), yeast infections of the skin (Cutaneous candidiasis), and pityriasis versicolor. It is also used for fungal nail infections.

How does NAILROX 1% CREAM work?

The active ingredient in NAILROX 1% CREAM, Ciclopirox, works by disrupting the growth and spread of fungi. It does this by interfering with essential biological processes within fungal cells, specifically by chelating trivalent cations (like iron and aluminum) that are vital for fungal cell membrane synthesis and division. Ciclopirox also inhibits metal-dependent enzymes, leading to an accumulation of toxic peroxides that damage and ultimately kill the fungal cells.

What is the usual dosage and how should it be applied?

NAILROX 1% CREAM is for external use only. Before applying, ensure your hands and the affected skin area are clean and dry. Apply a thin layer of the cream to the affected area and gently massage it until absorbed. The exact dosage and duration of treatment should be followed as prescribed by your doctor. It is important to use the cream consistently for optimal results.

What are the possible side effects of NAILROX 1% CREAM?

Common side effects often include local reactions at the application site, such as a burning sensation, itching, redness, pain, or irritation. In some cases, a skin rash or hives may occur. These side effects are usually mild and temporary. If you experience severe discomfort or an allergic reaction, discontinue use and consult your doctor.

Is NAILROX 1% CREAM safe during pregnancy or breastfeeding?

During pregnancy, caution is advised, and NAILROX 1% CREAM should only be used if clearly indicated and after consulting your doctor, as the active ingredient, ciclopirox, may potentially be harmful to the developing fetus. For breastfeeding mothers, limited human data suggests a low risk to the baby, but it is still recommended to consult your doctor and avoid applying the cream to the breast area to prevent accidental ingestion by the infant.

Can NAILROX 1% CREAM be taken with other medications?

When applied topically, NAILROX 1% CREAM (Ciclopirox) has no known significant drug-drug interactions. However, it is always advisable to inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and other topical treatments you are currently using, to avoid any potential interactions.

What precautions should be taken while using NAILROX 1% CREAM?

NAILROX 1% CREAM is strictly for external use. Avoid contact with your eyes, mouth, and nose. If accidental contact occurs, rinse the area thoroughly with plenty of water. Do not apply the cream to open wounds or damaged skin, as this could increase its absorption into the body. Unless specifically instructed by your doctor, do not cover the treated area with bandages. Do not use this medicine if you have a known allergy to ciclopirox or any of its ingredients. It is generally not recommended for children under 10 years of age unless prescribed by a doctor.

What happens if a dose of NAILROX 1% CREAM is missed?

If you forget to apply a dose of NAILROX 1% CREAM, do so as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed one.

How should NAILROX 1% CREAM be stored?

Store NAILROX 1% CREAM below 25°C (or below 30°C as indicated on the packaging) in a cool, dry place, away from direct sunlight and moisture. Keep the tube tightly closed when not in use and ensure it is out of the sight and reach of children. Do not use the cream after its expiry date or if you notice any visible signs of deterioration, such as changes in color.