Apxenta 30 Mg Tablet (10 Tab)

Name

• Brand Name: APXENTA 30 MG TABLET
• Common Name: Apremilast
• Manufacturer: AJANTA PHARMA LIMITED

Composition APXENTA 30 MG TABLET contains Apremilast 30 mg as its active ingredient. Apremilast is a phosphodiesterase 4 (PDE4) inhibitor, which works by blocking the activity of PDE4, an enzyme involved in inflammatory processes.

Uses This medicine is prescribed for the management of:

• Moderate to severe plaque psoriasis, a skin condition characterized by red, scaly, thick, itchy patches.
• Active psoriatic arthritis, a type of arthritis that causes joint pain and swelling in individuals with psoriasis.
• Oral ulcers associated with Behçet's disease, a rare inflammatory disorder.

Dosage and Administration The typical dosage is 30 mg taken orally twice daily. Your doctor may start with a lower dose and gradually increase it over the first 6 days. Tablets should be swallowed whole with water, without crushing, chewing, or breaking them. APXENTA 30 MG TABLET can be taken with or without food. Adherence to a regular dosage schedule is crucial, and discontinuation should only occur upon a doctor's explicit instructions.

Side Effects Common side effects may include:

• Nausea, diarrhea, vomiting, stomach pain, indigestion
• Headache, back pain, upper respiratory tract infections
• Weight loss and loss of appetite

More serious side effects, though less common, can include depression and suicidal thoughts. Patients are advised to monitor for mood changes.

Precautions Before starting treatment, inform your doctor about all other medications you are taking. APXENTA 30 MG TABLET is generally not recommended for use in children and adolescents under 17 years of age. Pregnant or breastfeeding women should seek medical advice before using this medication. Caution is advised in patients with severe kidney problems, and dosage adjustments may be necessary. Regular weight monitoring is recommended as weight loss can occur. Patients with a history of depression or suicidal thoughts, severe gut problems, or certain sugar intolerances should also inform their doctor.

Storage Store APXENTA 30 MG TABLET in a cool and dry place, away from sunlight, typically between 10ºC and 25ºC or below 30ºC. Keep it out of sight and reach of children.

APXENTA 30 MG TABLET contains Apremilast and is manufactured by Ajanta Pharma Limited. It is primarily used to treat inflammatory conditions such as moderate to severe plaque psoriasis and psoriatic arthritis.

What is APXENTA 30 MG TABLET used for?

APXENTA 30 MG TABLET is prescribed for the management of moderate to severe plaque psoriasis, a skin condition characterized by red, scaly, itchy, and painful patches. It is also used to treat active psoriatic arthritis, which causes joint pain and swelling in people with psoriasis. Additionally, it may be used for oral ulcers associated with Behçet's disease.

How does APXENTA 30 MG TABLET work?

APXENTA 30 MG TABLET contains Apremilast, which is a phosphodiesterase 4 (PDE4) inhibitor. It works by blocking the action of specific chemical messengers in the body that are responsible for inflammation associated with psoriatic arthritis and psoriasis. By reducing these inflammatory mediators, it helps alleviate the signs and symptoms of these conditions.

What is the usual dosage for APXENTA 30 MG TABLET?

For moderate to severe plaque psoriasis, the typical starting dosage is 30 mg taken orally twice daily for the first 5 days, followed by a maintenance dosage of 30 mg twice daily. For active psoriatic arthritis, the recommended dosage is 30 mg taken orally twice daily. The tablets should be swallowed whole with water and can be taken with or without food. It is crucial to follow your doctor's instructions precisely.

What are the possible side effects of APXENTA 30 MG TABLET?

Common side effects may include nausea, diarrhea, vomiting, headache, and upper respiratory tract infections. Other possible side effects include stomach pain, loss of appetite, indigestion, back pain, tiredness, difficulty in sleeping, and weight loss. If these side effects persist or worsen, it is recommended to consult a healthcare provider. In rare cases, it may cause depression or suicidal thoughts, and should be avoided in patients with a history of depression.

Is APXENTA 30 MG TABLET safe during pregnancy or breastfeeding?

APXENTA 30 MG TABLET is generally considered unsafe during pregnancy, as animal studies have shown potential risks of baby loss or defects in the unborn baby. Pregnancy should be avoided during treatment with this medicine. For breastfeeding women, information regarding its use is not available, and it is advised to seek medical advice before taking this medication.

Can APXENTA 30 MG TABLET be taken with other medications?

It is essential to inform your doctor about all other medications, supplements, or herbal products you are currently taking to prevent potential drug interactions. APXENTA 30 MG TABLET is not recommended with medicines such as rifampicin (for tuberculosis), phenytoin, phenobarbital, and carbamazepine (for epilepsy), or St. John's Wort.

What precautions should be taken while taking APXENTA 30 MG TABLET?

Before starting treatment, inform your doctor if you have any allergies to Apremilast or its ingredients, a history of depression or suicidal thoughts, severe kidney problems, unintended weight loss, or conditions like severe diarrhea, nausea, and vomiting. Regular weight monitoring is recommended during treatment as weight loss can occur. Alcohol consumption should be avoided or approached with caution during treatment, as it may interfere with the medication's effectiveness and potentially worsen psoriasis symptoms. This medication is generally not recommended for children and adolescents under 17 years of age.

What happens if a dose of APXENTA 30 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should APXENTA 30 MG TABLET be stored?

APXENTA 30 MG TABLET should be stored in a cool and dry place, away from direct sunlight. It should be kept out of the sight and reach of children, and not stored above 30°C.